Deleted Journal, Journal Year: 2025, Volume and Issue: unknown
Published: April 15, 2025
Language: Английский
International Journal of Ceramic Engineering & Science, Journal Year: 2023, Volume and Issue: 6(1)
Published: Nov. 7, 2023
Abstract Both unwanted and induced crystallization can impact bioactivity, physical mechanical properties of bioactive glasses (BGs). Uncontrolled has negative consequences, rendering BGs unreliable. However, by manipulating the type, size, shape, quantity crystals in BGs, plenty opportunities arise for controlling, example, degradability, leading to unique applications improved performance. Understanding is a key step developing glass‐ceramics (BGCs), both fundamental experimental research aid design BGCs processing biological function. In this perspective, we discuss sources how controlled facilitates functionalization scaffolds, hybrids, coatings, composites, cements, fibers.
Language: Английский
Citations
13
Journal of Alloys and Compounds, Journal Year: 2024, Volume and Issue: 993, P. 174603 - 174603
Published: April 22, 2024
Language: Английский
Citations
5
Heliyon, Journal Year: 2024, Volume and Issue: 10(13), P. e33847 - e33847
Published: June 28, 2024
Language: Английский
Citations
5
Journal of Functional Biomaterials, Journal Year: 2022, Volume and Issue: 14(1), P. 23 - 23
Published: Dec. 31, 2022
Nano-/micron-sized bioactive glass (BG) particles are attractive candidates for both soft and hard tissue engineering. They can chemically bond to the host tissues, enhance new formation, activate cell proliferation, stimulate genetic expression of proteins, trigger unique anti-bacterial, anti-inflammatory, anti-cancer functionalities. Recently, composites based on biopolymers BG have been developed with various state-of-the-art techniques Gelatin, a semi-synthetic biopolymer, has attracted attention researchers because it is derived from most abundant protein in body, viz., collagen. It polymer that be dissolved water processed acquire different configurations, such as hydrogels, fibers, films, scaffolds. Searching "bioactive gelatin" tile Scopus renders 80 highly relevant articles published last ~10 years, which signifies importance composites. First, this review addresses basic concepts engineering, including healing mechanisms limitations ahead. Then, current knowledge gelatin/BG composition, processing properties summarized discussed applications. This explores physical, chemical mechanical features ion-release effects concerning osteogenic angiogenic responses vivo vitro. Additionally, recent developments BG/gelatin using 3D/4D printing engineering presented. Finally, perspectives challenges developing desirable regeneration tissues outlined.
Language: Английский
Citations
22
Journal of Nanoparticle Research, Journal Year: 2024, Volume and Issue: 26(5)
Published: April 29, 2024
Language: Английский
Citations
4
International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: unknown, P. 124847 - 124847
Published: Oct. 1, 2024
Language: Английский
Citations
4
Materials Chemistry and Physics, Journal Year: 2025, Volume and Issue: unknown, P. 130477 - 130477
Published: Jan. 1, 2025
Language: Английский
Citations
0
Biomaterials and Biosystems, Journal Year: 2025, Volume and Issue: 17, P. 100108 - 100108
Published: Feb. 15, 2025
This review focuses on recent advancements in the effective use of mesoporous bioactive glasses (MBG) treatment bone cancer, focusing Osteosarcoma (OS). Bone cancers are rare but associated with significant morbidity and mortality; often, aggressive is required. Conventional treatments such as surgery, radiation, chemotherapy often not enough. because surgery cannot completely remove tumor, without creating a critical size which defects larger than 2 cm that be repaired by physiological mechanisms. As result, patients face additional burden radiation chemotherapy. Scientists have been exploring new treatments, including hyperthermia-targeted therapy, polymeric nanoparticles, stem cell therapy. could potentially negatively impact healthy tissues organs. MBG offers promising alternative to chemotherapeutic agents ions for disease it acts multifunctional drug delivery system (DDS). In addition, can also engineered into scaffolds facilitate local growth factors drugs, thus promoting efficiency healing restoration. Therefore, current highlights various types reported past decade explores potential future paths enhance their cancer while giving insight already commercially available BGs used different bone-related disease.
Language: Английский
Citations
0
Deleted Journal, Journal Year: 2025, Volume and Issue: unknown
Published: March 3, 2025
Language: Английский
Citations
0
ACS Biomaterials Science & Engineering, Journal Year: 2025, Volume and Issue: unknown
Published: March 11, 2025
Roughly 1.71 billion people worldwide suffer from large bone abnormalities, which are the primary cause of disability. Traditional grafting procedures have several drawbacks that impair their therapeutic efficacy and restrict use in clinical settings. A great deal work has been done to create fresh, more potent strategies. Under these circumstances, a crucial technique for regeneration major lesions emerged: tissue engineering (BTE). BTE involves biomaterials can imitate natural design bone. To yet, no biological material able fully meet parameters perfect implantable material, even though varieties created investigated regeneration. Against this backdrop, researchers focused interest over past few years on subject nanotechnology nanostructures regenerative medicine. The ability nanoengineered particles overcome current constraints strategies─such as decreased cell proliferation differentiation, insufficient mechanical strength materials, production extrinsic factors required effective osteogenesis revolutionized field engineering. effects nanoparticles characteristics application materials main topics our review, summarizes most recent vitro vivo research context BTE.
Language: Английский
Citations
0