Pediatric Cochlear Implantation: Families Centered Intervention in Early Habilitation on Pediatric Cochlear Implantation DOI
Isabel Margarida Costa, Pedro V. Silva

Published: Jan. 1, 2024

Language: Английский

Effects of Environmental Non-Essential Toxic Heavy Metals on Epigenetics During Development DOI Creative Commons
Hisaka Kurita,

Kazuki Ohuchi,

Masatoshi Inden

et al.

Toxics, Journal Year: 2025, Volume and Issue: 13(3), P. 167 - 167

Published: Feb. 27, 2025

We are exposed to a variety of environmental chemicals in our daily lives. It is possible that the effects this chemical exposure could accumulate organism some form and influence health disease development. The extend throughout human lifetime, not only after birth, but also during embryonic period. Epigenetics an important target for molecular mechanisms effects. mechanism gene transcription regulation does involve changes DNA sequence. Developmental Origins Health Disease (DOHaD) theory has been proposed, which such as period mediated by epigenetic changes, may lead risk development adverse maturity. This review summarizes association between epigenetics well-known non-essential toxic heavy metals (methylmercury, cadmium, arsenic, lead), representative group chemicals. In future, it will be predict unknown combined exposures. addition, further experimental investigations using animals accumulation knowledge needed study transgenerational future.

Language: Английский

Citations

1
Systematic review on Endocrine Disrupting Chemicals in breastmilk and neuro-behavioral development: insight into the early ages of life DOI Creative Commons

Maddalena Brambilla,

Serafina Perrone, Anna-Mariia Shulhai

et al.

Neuroscience & Biobehavioral Reviews, Journal Year: 2025, Volume and Issue: unknown, P. 106028 - 106028

Published: Jan. 1, 2025

Language: Английский

Citations

0
Introduction to the Special Issue on Developmental Plasticity in Early Human Development DOI
Meghan H. Puglia, David S. Moore, Robert Lickliter

et al.

Infancy, Journal Year: 2025, Volume and Issue: 30(1)

Published: Jan. 1, 2025

Language: Английский

Citations

0
Functional brain connectivity predictors of prospective substance use initiation and their environmental correlates DOI Creative Commons
Omid Kardan, Alexander Weigard,

Lora M. Cope

et al.

Biological Psychiatry Cognitive Neuroscience and Neuroimaging, Journal Year: 2024, Volume and Issue: 10(2), P. 203 - 212

Published: Oct. 25, 2024

Language: Английский

Citations

1
Brain age prediction and deviations from normative trajectories in the neonatal connectome DOI Creative Commons
Huili Sun, Saloni Mehta, Milana Khaitova

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: Nov. 26, 2024

Structural and functional connectomes undergo rapid changes during the third trimester first month of postnatal life. Despite progress, our understanding developmental trajectories connectome in perinatal period remains incomplete. Brain age prediction uses machine learning to estimate brain's maturity relative normative data. The difference between individual's predicted chronological age—or brain gap (BAG)—represents deviation from these trajectories. Here, we assess BAGs using structural for infants We use resting-state fMRI DTI data 611 (174 preterm; 437 term) Developing Human Connectome Project (dHCP) connectome-based predictive modeling predict postmenstrual (PMA). accurately PMA term preterm infants. Predicted ages each modality are correlated. At network level, nearly all canonical networks—even putatively later developing ones—generate accurate prediction. Additionally, associated with exposures toddler behavioral outcomes. Overall, results underscore importance deviations models period. authors show that altered development after birth, driven by exposures, influences long-term cognitive

Language: Английский

Citations

1
Reproductive Technologies and Parkinson’s disease: A Study of the Substantia Nigra and Motor Functions in C57BL/6 and B6.CG-TG Mice DOI

V. S. Kozeneva,

I. N. Rozhkova,

E. Yu. Brusentsev

et al.

Journal of Evolutionary Biochemistry and Physiology, Journal Year: 2024, Volume and Issue: 60(6), P. 2434 - 2450

Published: Nov. 1, 2024

Language: Английский

Citations

1
Functional brain connectivity predictors of prospective substance use initiation and their environmental correlates DOI Creative Commons
Omid Kardan, Alexander Weigard,

Lora M. Cope

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: May 31, 2024

Early substance use initiation (SUI) places youth at substantially higher risk for later disorders. Furthermore, adolescence is a critical period the maturation of brain networks, pace and magnitude which are susceptible to environmental influences may shape SUI.

Language: Английский

Citations

0
Pediatric Cochlear Implantation: Families Centered Intervention in Early Habilitation on Pediatric Cochlear Implantation DOI
Isabel Margarida Costa, Pedro V. Silva

Published: Jan. 1, 2024

Language: Английский

Citations

0