Recent Advances in Biomedical, Therapeutic and Pharmaceutical Applications of Microbial Surfactants DOI Creative Commons
Chiara Ceresa, Letizia Fracchia,

Emanuele Fedeli

et al.

Pharmaceutics, Journal Year: 2021, Volume and Issue: 13(4), P. 466 - 466

Published: March 30, 2021

The spread of antimicrobial-resistant pathogens typically existing in biofilm formation and the recent COVID-19 pandemic, although unrelated phenomena, have demonstrated urgent need for methods to combat such increasing threats. New avenues research natural molecules with desirable properties alleviate this situation have, therefore, been expanding. Biosurfactants comprise a group unique varied amphiphilic microbial origin capable interacting lipidic membranes/components microorganisms altering their physicochemical properties. These features encouraged closer investigations these metabolites as new pharmaceutics potential applications clinical, hygiene therapeutic fields. Mounting evidence has indicated that biosurfactants antimicrobial, antibiofilm, antiviral, immunomodulatory antiproliferative activities are exploitable anticancer treatments wound healing applications. Some already approved use food environmental fields, while others currently under investigation development antimicrobials or adjuvants antibiotics suppression eradication strategies. Moreover, due now being explored an alternative current products procedures effective cleaning handwash formulations, antiviral plastic fabric surface coating agents shields masks. In addition, shown promise drug delivery systems medicinal relief symptoms associated SARS-CoV-2 acute respiratory distress syndrome.

Language: Английский

Biosurfactants, natural alternatives to synthetic surfactants: Physicochemical properties and applications DOI

Ruksana Jahan,

Andrew M. Bodratti,

Marina Tsianou

et al.

Advances in Colloid and Interface Science, Journal Year: 2019, Volume and Issue: 275, P. 102061 - 102061

Published: Nov. 9, 2019

Language: Английский

Citations

433
Vaginal microbiota and the potential of Lactobacillus derivatives in maintaining vaginal health DOI Creative Commons
Wallace Jeng Yang Chee, Shu Yih Chew, Leslie Thian Lung Than

et al.

Microbial Cell Factories, Journal Year: 2020, Volume and Issue: 19(1)

Published: Nov. 7, 2020

Abstract Human vagina is colonised by a diverse array of microorganisms that make up the normal microbiota and mycobiota. Lactobacillus most frequently isolated microorganism from healthy human vagina, this includes crispatus , gasseri iners jensenii . These vaginal lactobacilli have been touted to prevent invasion pathogens keeping their population in check. However, disruption ecosystem contributes overgrowth which causes complicated infections such as bacterial vaginosis (BV), sexually transmitted (STIs), vulvovaginal candidiasis (VVC). Predisposing factors menses, pregnancy, sexual practice, uncontrolled usage antibiotics, douching can alter microbial community. Therefore, composition serves an important role determining health. Owing Generally Recognised Safe (GRAS) status, widely utilised one alternatives besides conventional antimicrobial treatment against for prevention chronic vaginitis restoration ecosystem. In addition, effectiveness prophylaxis has also well-founded long-term administration. This review aimed highlight beneficial effects derivatives (i.e. surface-active molecules) with anti-biofilm, antioxidant, pathogen-inhibition, immunomodulation activities developing remedies infections. We discuss current challenges implementation use promotion review, we intend provide insights development complementary or alternative medicine probiotic therapy

Language: Английский

Citations

415
A review on biosurfactants: properties, applications and current developments DOI
Anoop R. Markande,

Divya D. Patel,

Sunita Varjani

et al.

Bioresource Technology, Journal Year: 2021, Volume and Issue: 330, P. 124963 - 124963

Published: March 12, 2021

Language: Английский

Citations

275
Biosurfactants: Production, properties, applications, trends, and general perspectives DOI Creative Commons
Leonie Asfora Sarubbo, Maria da Glória C. Silva, Ítalo José Batista Durval

et al.

Biochemical Engineering Journal, Journal Year: 2022, Volume and Issue: 181, P. 108377 - 108377

Published: Feb. 17, 2022

Biosurfactants have become attractive microbial products in the emerging biotechnology industry due to their advantages over synthetic surfactants terms of environmental sustainability, global public health, and concerns industries produce environmentally friendly goods. The amphipathic structure biosurfactants with hydrophilic hydrophobic moieties enable these molecules play a key role emulsification, foam formation, detergency, oil dispersion activities, which are desirable traits different industries. Several types commercially produced for applications pharmaceutical cosmetic while others promising roles food, petroleum, agricultural In this paper, we offer an extensive review knowledge on accumulated years. We also discuss current industrial as well challenges development applications.

Language: Английский

Citations

256
Production of green surfactants: Market prospects DOI Creative Commons
Charles Bronzo Barbosa Farias, F. C. G. Almeida,

Ivison A. Silva

et al.

Electronic Journal of Biotechnology, Journal Year: 2021, Volume and Issue: 51, P. 28 - 39

Published: March 12, 2021

Science has greatly contributed to the advancement of technology and innovation production processes their applications. Cleaning products have become indispensable in today's world, as personal environmental hygiene is important all societies worldwide. Such are used home, most work environments industrial sectors. Most detergents on market synthesised from petrochemical products. However, interest reducing use harmful human health environment led search for formulated with natural, biodegradable surfactant components biological (plant or microbiological) origin chemically natural raw materials usually referred green surfactants. This review addresses different types, properties, uses surfactants, a focus describes current scenario well projections future economy related types surfactants marketed world. How cite: Farias CBB, Almeida FCG, Silva IA, et al. Production surfactants: Market prospects. Electron J Biotechnol 2021;51. https://doi.org/10.1016/j.ejbt.2021.02.002

Language: Английский

Citations

238
Microbial biosurfactants: a review of recent environmental applications DOI Open Access

Estefanía Eras-Muñoz,

Abel Farré,

Antoni Sánchez

et al.

Bioengineered, Journal Year: 2022, Volume and Issue: 13(5), P. 12365 - 12391

Published: May 2, 2022

Microbial biosurfactants are low-molecular-weight surface-active compounds of high industrial interest owing to their chemical properties and stability under several environmental conditions. The chemistry a biosurfactant its production cost defined by the selection producer microorganism, type substrate, purification strategy. Recently, have been applied solve or contribute solving some problems, with this being main field application. most referenced studies based on bioremediation contaminated soils recalcitrant pollutants, such as hydrocarbons heavy metals. In case metals, function chelating agents binding capacity. However, mechanism which typically act in an is focused ability reduce surface tension, thus facilitating emulsification solubilization certain pollutants (in-situ biostimulation and/or bioaugmentation). Moreover, despite low toxicity biosurfactants, they can also biocidal at doses, mainly higher concentrations than critical micellar concentration. More recently, using alternative substrates, types organic waste solid-state fermentation, has increased applicability research circular economy context. review, recent publications use applications conventional surfactants summarized analyzed. Novel strategies agricultural presented paper.

Language: Английский

Citations

165
Green Surfactants (Biosurfactants): A Petroleum-Free Substitute for Sustainability─Comparison, Applications, Market, and Future Prospects DOI Creative Commons

Vaishnavi S. Nagtode,

Clive Cardoza,

Haya Yasin

et al.

ACS Omega, Journal Year: 2023, Volume and Issue: 8(13), P. 11674 - 11699

Published: March 24, 2023

Surfactants are a group of amphiphilic molecules (i.e., having both hydrophobic and hydrophilic domains) that vital part nearly every contemporary industrial process such as in agriculture, medicine, personal care, food, petroleum. In general surfactants can be derived from (i) petroleum-based sources or (ii) microbial/plant origins. Petroleum-based obvious results petroleum products, which lead to pollution thus pose severe problems the environment leading various ecological damages. Thus, newer techniques have been suggested for deriving surfactant maintaining environmental sustainability. Biosurfactants microbial plant origins offer much added advantages high biodegradability, lesser toxicity, ease raw material availability, easy applicability. they also termed "green surfactants". this regard, review focused on biosurfactants over synthetic produced products along with their potential applications different industries. We provided market aspects future directions considered selections biosurfactants. This would open up new avenues research by overcoming existing bottlenecks field.

Language: Английский

Citations

161
Microbial Biosurfactants in Cosmetic and Personal Skincare Pharmaceutical Formulations DOI Creative Commons
Simms A. Adu, Patrick Naughton, Roger Marchant

et al.

Pharmaceutics, Journal Year: 2020, Volume and Issue: 12(11), P. 1099 - 1099

Published: Nov. 16, 2020

Cosmetic and personal care products are globally used often applied directly on the human skin. According to a recent survey in Europe, market value of cosmetic Western Europe reached about 84 billion euros 2018 predicted increase by approximately 6% end 2020. With these significant sums money spent annually products, along with chemical surfactants being main ingredient number their formulations, which many have been reported potential cause detrimental effects such as allergic reactions skin irritations skin; hence, need for replacement other compounds that would less or no negative health. Biosurfactants (surfactants biological origin) exhibited great lower toxicity, compatibility, protection surface moisturizing key components an effective skincare routine. This review discusses antimicrobial, low toxicity properties glycolipid lipopeptide biosurfactants could make them suitable substitutes current pharmaceutical formulations. Finally, we discuss some challenges possible solutions biosurfactant applications.

Language: Английский

Citations

157
A review on new aspects of lipopeptide biosurfactant: Types, production, properties and its application in the bioremediation process DOI
C. Femina Carolin, P. Senthil Kumar,

P. Tsopbou Ngueagni

et al.

Journal of Hazardous Materials, Journal Year: 2020, Volume and Issue: 407, P. 124827 - 124827

Published: Dec. 11, 2020

Language: Английский

Citations

156
Biosurfactants in Plant Protection Against Diseases: Rhamnolipids and Lipopeptides Case Study DOI Creative Commons
Jérôme Crouzet, Anthony Argüelles Arias, Sandrine Dhondt‐Cordelier

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2020, Volume and Issue: 8

Published: Sept. 8, 2020

Biosurfactants are amphiphilic surface-active molecules that produced by a variety of microorganisms including fungi and bacteria. Pseudomonas, Burkholderia Bacillus species known to secrete rhamnolipids lipopeptides used in wide range industrial applications. Recently, these compounds have been studied context plant-microbe interactions. This mini-review describes the direct antimicrobial activities against plant pathogens. We also provide current knowledge on how stimulate immune system leading resistance phytopathogens. Given their low toxicity, high biodegradability ecological acceptance, we discuss possible role biosurfactants as alternative strategies reduce or even replace pesticide use agriculture.

Language: Английский

Citations

150