Behavior of Gingival Fibroblasts on Titanium Implant Surfaces in Combination with either Injectable-PRF or PRP

International Journal of Molecular Sciences, Journal Year: 2017, Volume and Issue: 18(2), P. 331 - 331

Published: Feb. 4, 2017

Various strategies have been employed to speed tissue regeneration using bioactive molecules. Interestingly, platelet concentrates derived from a patient's own blood utilized as regenerative strategy in recent years. In the present study, novel liquid formulation prepared without use of anti-coagulants (injectable-platelet-rich fibrin, i-PRF) was compared standard platelet-rich plasma (PRP) with gingival fibroblasts cultured on smooth and roughened titanium implant surfaces. Standard PRP i-PRF (centrifuged at 700 rpm (60×

Language: Английский

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Soft tissue‐related complications and management around dental implants

Periodontology 2000, Journal Year: 2019, Volume and Issue: 81(1), P. 124 - 138

Published: Aug. 12, 2019

Abstract Implant installation for replacing missing teeth is a frequent treatment procedure with high long‐term survival and success rates. However, the of implant therapy may be jeopardized by several complications related to mistakes in planning, surgical procedure, management hard soft tissues, infections. Increasing evidence suggests that stability tissues surrounding osseointegrated dental implants substantially influence clinical esthetics. Therefore, when planned, clinician must not only able perform appropriate steps maintain/create stable tissue, but also needs aware potential sources possess adequate knowledge their management. The present paper provides an overview most important aspects prevention tissue‐related conjunction therapy. current literature indicates presence width keratinized attached mucosa around lead better tissue stability, less plaque accumulation, limited recession, lower incidence peri‐implant mucositis. Proper positioning carefully considering mesio‐distal bucco‐lingual dimensions angulation prevent loss interdental development recessions. To optimize mucosa, augmentation protocol should selected each particular indication. When use autogenous grafts thorough anatomical structures mandatory order harvest quality quantity avoid/minimize postoperative complications. Finally, master necessary manage extensive bleeding necrosis occur procedures.

Language: Английский

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Effect of Platelet Rich Fibrin (PRF) on Peri-implant Soft Tissue and Crestal Bone in One-Stage Implant Placement: A Randomized Controlled Trial

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, Journal Year: 2015, Volume and Issue: unknown

Published: Jan. 1, 2015

The viability of Platelet Rich Fibrin (PRF) on enhancement osseous and associated tissue healing has been substantiated well in literature. However, paucity the applicability PRF to enhance peri-implant oral region is not well-corroborated.This prospective study evaluated effect response following one-stage implant placement with non-functional immediate provisionalization maxillary anterior region.A Prospective, Randomized Controlled Trial (RCT) was conducted across 20 (15 male, 5 Female) systemically healthy subjects maintainable hygiene. Subjects were broadly divided into two groups i.e. Study group (PRF group) Control (Non-PRF group). Twenty standard SLA- AB/AE (alumina oxide blasted/acid etched surface treated) tapered threaded dental implants randomly placed without immediately provisionalized. clinically radiographically at baseline (at time placement), one month three post-operatively for soft crestal bone responses.At 3 months, all remained osseointegrated. mean marginal changes observed from months both lesser Group. No significant differences probing depth bleeding noted during follow-up.Within limitations this study, could be considered as a biomaterial potential beneficial can used therapeutic adjuvant clinical scenario stage, single tooth procedure region.

Language: Английский

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Strategies for Optimizing the Soft Tissue Seal around Osseointegrated Implants

Advanced Healthcare Materials, Journal Year: 2017, Volume and Issue: 6(20)

Published: Sept. 27, 2017

Abstract Percutaneous and permucosal devices such as catheters, infusion pumps, orthopedic, dental implants are commonly used in medical treatments. However, these useful breach the soft tissue barrier that protects body from outer environment, thus increase bacterial infections resulting morbidity mortality. Such associated can be prevented if effectively integrated with surrounding tissue, creating a strong seal environment. so far, there no percutaneous/permucosal able to prevent infection by achieving integration at tissue–device interface. This review gives an insight into current status of research tissue–implant interface challenges interfaces. Biological soft/hard interfaces may provide insights toward engineering better around percutaneous devices. In this review, focus is put on history findings well recent progress strategies aiming develop osseointegrated implants, orthopedic implants.

Language: Английский

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Classification of facial peri‐implant soft tissue dehiscence/deficiencies at single implant sites in the esthetic zone

Journal of Periodontology, Journal Year: 2019, Volume and Issue: 90(10), P. 1116 - 1124

Published: May 14, 2019

The incidence of a peri-implant soft tissue dehiscence/deficiency (PSTD) is not rare finding. Despite multiple previous attempts aimed at correcting the PSTDs, classification these conditions has yet been proposed. This lack in literature may also lead to discrepancies reported treatment outcomes and thus misinform clinician or readers. aim present article was therefore PSTD single implant site.Four classes PSTDs were discussed based on position gingival margin implant-supported crown relation homologous natural tooth. In addition, bucco-lingual head taken into consideration. Each class further subdivided height anatomical papillae.Subsequently, for each respective category surgical approach (including bilaminar techniques, combined prosthetic-surgical augmentation with submerged healing) suggested.This paper provides new system describing sites, appropriate recommended protocol.

Language: Английский

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Research status of biodegradable metals designed for oral and maxillofacial applications: A review

Bioactive Materials, Journal Year: 2021, Volume and Issue: 6(11), P. 4186 - 4208

Published: April 27, 2021

The oral and maxillofacial regions have complex anatomical structures different tissue types, which vital health aesthetic functions. Biodegradable metals (BMs) is a promising bioactive materials to treat diseases. This review summarizes the research status future directions of BMs for applications. Mg-based Zn-based bone fracture fixation systems, guided regeneration (GBR) membranes, are discussed in detail. with moderate degradation rate superior mechanical properties GBR membranes show great potential clinical translation. Fe-based relatively low insoluble products, greatly limit their application Furthermore, we proposed regions, including 3D printed BM scaffolds, surface modification containing hydrogels cartilage regeneration, soft nerve regeneration. Taken together, progress made development has laid foundation further

Language: Английский

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Oral microbiome and peri-implant diseases: where are we now?

Therapeutics and Clinical Risk Management, Journal Year: 2017, Volume and Issue: Volume 13, P. 1529 - 1542

Published: Nov. 1, 2017

Peri-implant infective diseases (PIIDs) in oral implantology are commonly known as peri-implant mucositis (PIM) and periimplantitis (PI). While PIM is restricted to the mucosa reversible, PI also affects implant-supporting bone and, therefore, very difficult eradicate. PIIDs clinical outcome may resemble gingivitis periodontitis, they share similar risk factors. However, recent study field of proteomics other molecular studies indicate that exhibit significant differences when compared periodontal diseases. This review aims elucidate current knowledge PIIDs, their etiopathology diversified microbiology well role studies, which be a key personalized diagnostic treatment protocols infections near future.

Language: Английский

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Diabetic wound healing in soft and hard oral tissues

Translational research, Journal Year: 2021, Volume and Issue: 236, P. 72 - 86

Published: May 13, 2021

Language: Английский

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Acellular dermal matrix and coronally advanced flap or tunnel technique in the treatment of multiple adjacent gingival recessions. A 12‐year follow‐up from a randomized clinical trial

Journal Of Clinical Periodontology, Journal Year: 2019, Volume and Issue: 46(9), P. 937 - 948

Published: June 26, 2019

Abstract Aim To evaluate the long‐term outcomes of Acellular Dermal Matrix (ADM) with Coronally Advanced Flap (CAF) or Tunnel technique (TUN) in treatment multiple adjacent gingival recessions (MAGRs). Material and methods Nineteen original 24 patients contributing to a total number 33 sites for CAF 34 TUN were available 12 years follow‐up examination. Recession depth, mean root coverage (mRC), keratinized tissue width (KTW), thickness (GT) evaluated compared baseline values 6‐months results. Regression analysis was performed identify factors related stability margin. Results A highly significant drop mRC observed both groups from 6 months timepoint recall ( p < .001). While there no statistically differences between two terms Clinical Attachment Level (CAL), KTW, GT changes Root Coverage Esthetic Score at each > .05). KTW ≥ 2 mm 1.2 predictors margin = .03 .01, respectively). Conclusions relapse MAGRs treated + ADM after years.

Language: Английский

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Vascularization strategies in tissue engineering approaches for soft tissue repair

Journal of Tissue Engineering and Regenerative Medicine, Journal Year: 2021, Volume and Issue: 15(9), P. 747 - 762

Published: May 25, 2021

Insufficient vascularization during tissue repair is often associated with poor clinical outcomes. This a concern especially when patients have critical-sized injuries, where the size of defect restricts vascularity, or even in small defects that to be treated under special conditions, such as after radiation therapy (relevant tumor resection) hinders vascularity. In fact, one major obstacles for application engineering methods soft repair. As key issue, lack graft integration, caused by inadequate implantation, can lead failure. Moreover, compromises viability cells seeded deep portions scaffolds/graft materials, due hypoxia and insufficient nutrient supply. this article we aim review strategies employed techniques tissues. For purpose, start providing brief overview main events physiological wound healing process Then, discuss how achieved through engineering, considerations regards choice scaffold culture techniques. Next, highlight importance vascularization, along prevascularization equivalents, particularly cell-based prevascularization. Lastly, present summary commonly used vitro tissue-engineered constructs.

Language: Английский

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