Association between monocyte-to-lymphocyte ratio and cardiovascular diseases: insights from NHANES data

Diabetology & Metabolic Syndrome, Journal Year: 2025, Volume and Issue: 17(1)

Published: March 24, 2025

Abstract Background This study intends to examine any possible correlation between monocyte-to-lymphocyte ratio (MLR) and cardiovascular diseases (CVD). Methods Data from the 1999–2020 National Health Nutrition Examination Survey (NHANES) in USA were analyzed. Heart attacks, angina pectoris, congestive heart failure (CHF), coronary disease (CHD), stroke all covered by CVD. The independent relationships these events MLR levels, as well other inflammatory indices (system inflammation response index (SIRI), aggregate of systemic (AISI), C-reactive protein-to-albumin (CAR)), investigated. Furthermore, interaction tests subgroup analysis performed. Diagnostic capacities also predicted compared using receiver operating characteristic (ROC) curves. Results Males made up 49.63% 46,289 people who recruited this study. prevalence CVD its follows: CHF at 2.99%, CHD 3.72%, pectoris 2.57%, attacks 3.94%, 3.48%, with itself 7.98%. positively correlated. Specifically, smooth curve fittings found a non-linear relationship Moreover, higher levels linked increased rates CHF, CHD, strokes. SIRI wa s have positive outperformed (SIRI, AISI, CAR) terms discriminative capacity accuracy predicting CVD, attack, stroke, according ROC analysis. Conclusions Compared indicators CAR), appears be better for stroke. American adults elevated should aware harm caused Causal inference is, however, limited cross-sectional design dependence on self-reported data. Further longitudinal studies are needed validate findings.

Language: Английский

Association of hemoglobin, albumin, lymphocyte, and platelet score with all-cause and cardiovascular mortality in adults with diabetes or prediabetes: Results from NHANES 2005–2018

Preventive Medicine Reports, Journal Year: 2025, Volume and Issue: unknown, P. 103101 - 103101

Published: May 1, 2025

Language: Английский

Association between nickel and multiple metabolic outcomes: The mediating roles of lipid metabolism and inflammation

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 298, P. 118274 - 118274

Published: May 6, 2025

Language: Английский