A chlorin e6 derivative-mediated photodynamic therapy versus doxycycline for moderate-to-severe rosacea: A prospective, randomized, controlled study
Photodiagnosis and Photodynamic Therapy,
Journal Year:
2025,
Volume and Issue:
unknown, P. 104474 - 104474
Published: Jan. 1, 2025
Photodynamic
therapy
(PDT)
is
beneficial
for
managing
rosacea,
and
chlorin
e6
derivative-mediated
photodynamic
(STBF-PDT)
has
demonstrated
efficacy
in
reducing
acne
lesions
with
mild
adverse
reactions.
This
study
aimed
to
assess
the
effectiveness
safety
of
STBF-PDT
treatment
moderate-to-severe
rosacea.
In
this
prospective,
randomised,
evaluator-blind
controlled
study,
patients
rosacea
were
assigned
receive
up
six
sessions
or
100
mg
doxycycline
daily
eight
weeks,
followed
by
a
24-week
follow-up.
A
total
76
enrolled
(38
38
oral
doxycycline)
69
(36
group
33
group)
completing
study.
At
end
treatment,
median
reduction
lesion
count
was
82.3%
81.8%
group,
indicating
no
significant
difference
between
groups.
The
exhibited
lower
relapse
rate
significantly
higher
Demodex
mites.
Clinician's
Erythema
Assessment
success
(CEA),
sensations
burning
pruritus,
telangiectasia,
Rosacea-related
Quality
Life
(RosaQoL)
scores
comparable
No
severe
reactions
observed.
promising
option
mild-to-moderate
Language: Английский
Peau et psychisme : le vrai et le faux
Annales de Dermatologie et de Vénéréologie - FMC,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Downregulation of the NPY-Y1R system in Grpr neurons results in mechanical and chemical hyperknesis in chronic itch
Danqing Dai,
No information about this author
Zongxi Li,
No information about this author
Tiantian Zhao
No information about this author
et al.
Neurobiology of Disease,
Journal Year:
2025,
Volume and Issue:
unknown, P. 106806 - 106806
Published: Jan. 1, 2025
Language: Английский
Psychologische Aspekte in der Berufsdermatologie
Maurice Waitek,
No information about this author
Elke Weißhaar
No information about this author
Deleted Journal,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 22, 2025
The
prevalence
of
psychological
disorders
in
the
general
population
and,
therefore,
dermatological
and
allergological
patients
continues
to
increase.
Psychodermatology
as
a
branch
dermatology
is
also
becoming
ever
more
relevant
occupational
dermatology.
Psychological
comorbidities
cofactors
like
depression
anxiety
or
stress
are
increasingly
important,
which
must
be
considered
regarding
diagnostics
therapy
selection.
Especially
recognized
possible
aggravating
factor.
There
have
been
numerous
studies
on
selected
clinical
diseases
atopic
dermatitis
(AD)
influence
disease
recent
years,
but
for
hand
eczema
(HE),
especially
HE,
there
hardly
any
data,
causality.
Stress
seems
play
an
important
role
work
environment
their
private
lives.
This
article
provides
overview
dermatoses.
current
literature
our
own
observations
experiences
center
taken
into
account.
Language: Английский
The Relationship Between Chronic Pruritus, Attention-Deficit/Hyperactivity Disorder, and Skin Picking—A Case Series and Narrative Review
Eva Loos,
No information about this author
Suzan Sekar,
No information about this author
Christiane Rosin
No information about this author
et al.
Journal of Clinical Medicine,
Journal Year:
2025,
Volume and Issue:
14(5), P. 1774 - 1774
Published: March 6, 2025
Chronic
pruritus
(CP),
attention-deficit/hyperactivity
disorder
(ADHD),
and
skin
picking
(SPD)
are
medical
conditions
that
involve
both
somatic
psychosocial
dimensions,
posing
unique
challenges
in
clinical
management.
While
CP
SPD
often
observed
together,
the
link
between
ADHD
these
is
less
recognized.
This
conceptual
work
describes
three
women
who
suffered
from
a
complex
interplay
of
CP,
ADHD,
treated
at
our
specialized
bi-disciplinary
psychodermatological
clinic.
Based
on
observation
narrative
review
literature,
we
assume
bidirectional,
triangular
relationship
SPD.
To
support
this
assumption,
propose
two
hypotheses:
(1)
neurodevelopmental
hypothesis,
emphasizing
an
underlying
disorder,
case,
might
present
with
symptoms
like
dysfunction
sensory
processing,
impulsivity,
attention
deficits
as
shared
features
reinforce
SPD,
(2)
neuroinflammatory
suggesting
similar
signatures
promote
co-occurrence
In
addition,
provide
specific
suggestions
derived
experience
how
to
manage
patients
combination
conditions.
Elucidating
help
develop
personalized
treatment
strategies
improve
outcomes.
Language: Английский
Patient and Healthcare Provider Perspectives on Disease Burden of Seborrheic Dermatitis in the United States: Results from a National Survey
Dermatology and Therapy,
Journal Year:
2024,
Volume and Issue:
14(11), P. 3083 - 3095
Published: Oct. 28, 2024
Seborrheic
dermatitis
(SD)
is
a
common,
chronic
inflammatory
skin
disease,
but
the
physical
and
emotional
burden
of
patients
with
SD
experience
has
not
been
well
characterized.
The
Harris
Poll
conducted
online
surveys
US
healthcare
providers
(HCPs)
from
December
2021
to
January
2022.
Almost
half
reported
that
negatively
impacts
their
well-being
"a
lot/a
great
deal";
HCPs
underestimate
level
impact
on
patients.
Most
significant
mental
health
impact,
including
anxiety,
depression,
anxiety
about
interacting
other
people,
isolation.
Two-thirds
said
they
did
know
anyone
else
who
had
diagnosed
SD,
even
after
diagnosis,
less
than
still
SD.
Nearly
all
agreed
it
was
challenging
hide
symptoms,
most
felt
embarrassed
when
people
commented
symptoms.
would
be
further
along
in
career
if
have
symptoms
made
them
confident
at
work
likely
want
interact
work.
ever
missing
as
result
These
insights
emphasize
patient
associated
impacting
aspects
patients'
lives.
Graphical
abstract
available
for
this
article.
Language: Английский
Seborrheic Dermatitis: From Microbiome and Skin Barrier Involvement to Emerging Approaches in Dermocosmetic Treatment
Cosmetics,
Journal Year:
2024,
Volume and Issue:
11(6), P. 208 - 208
Published: Nov. 28, 2024
Seborrheic
dermatitis
(SD)
is
a
chronic
inflammatory
skin
disease
that
primarily
affects
sebaceous-rich
areas
such
as
the
scalp,
face,
and
upper
trunk.
While
precise
etiology
remains
multifactorial,
role
of
microbiome,
particularly
proliferation
Malassezia
species,
alterations
in
barrier
function
are
critical
its
pathogenesis.
Disruption
barrier,
characterized
by
increased
transepidermal
water
loss
(TEWL)
reduced
production
epidermal
lipids,
creates
favorable
environment
for
microbial
overgrowth
inflammation.
Recent
insights
highlight
interplay
between
impaired
function,
immune
responses,
microbiome
perpetuating
disease.
Additionally,
novel
dermocosmetic
approaches
emerging
target
these
underlying
mechanisms,
offering
promising
therapeutic
avenues.
This
review
provides
comprehensive
overview
involvement
dysfunction
seborrheic
discusses
potential
advanced
treatments
aimed
at
restoring
homeostasis
preventing
recurrence.
Language: Английский
Prevalence, risk factors and management approaches for seborrheic dermatitis
International Journal of Research in Medical Sciences,
Journal Year:
2024,
Volume and Issue:
13(1), P. 90 - 95
Published: Dec. 31, 2024
Background:
Seborrheic
dermatitis
(SD)
is
a
chronic
inflammatory
condition
characterized
by
immune
dysregulation,
inflammation
and
disruption
of
the
skin
barrier.
Despite
its
global
prevalence,
with
studies
indicating
that
up
to
5%
population
may
be
affected,
study
physical
emotional
impact
SD
on
patients
limited.
Furthermore,
prevalence
appears
increasing
over
time.
Therefore,
this
aimed
determine
risk
factors
management
approaches
for
seborrheic
dermatitis.
Methods:
This
was
prospective
conducted
in
Department
Skin
VD,
Community
Based
Medical
College
Bangladesh,
Mymensingh,
Bangladesh
during
period
from
June
2020
2022.
In
our
study,
we
included
150
who
visited
VD
at
Bangladesh.
Results:
Among
patients,
55%
were
male
45%
female.
all
reported
56
(71%)
had
moderate
level
SD,
followed
mild
(16%)
severe
(13%).
HCP
(Health
care
provider)
suggested
41%
them
(40%)
(19%).
Out
50%
not
allowed
miss
their
jobs
due
symptoms.
Conclusions:
The
findings
highlight
importance
holistic
approach
managing
should
encompass
only
treatment
signs
symptoms
disease
but
also
psychological
social
challenges
face.
Language: Английский