Patient Preference and Adherence,
Journal Year:
2021,
Volume and Issue:
Volume 15, P. 2197 - 2208
Published: Sept. 1, 2021
Purpose:
To
explore
how
adult
patients
perceive
deprescribing
in
a
country
with
developing
pharmaceutical
care.
Patients
and
Methods:
This
was
multicenter
cross-sectional
study
conducted
ten
community
pharmacies
across
Croatia.
Community-dwelling
adults
40
years
older,
taking
at
least
one
prescription
medication
long
term,
were
invited
to
participate.
The
revised
validated
Patients'
Attitude
Towards
Deprescribing
Questionnaire
used
investigate
community-dwelling
adults'
opinions
on
potential
discontinuation.
Questions
regarding
the
patients'
perception
of
pharmacist
competences
involvement
as
well
preferences
added.
Collected
data
analyzed
using
IBM
SPSS
Statistics
descriptive
inferential
statistical
analysis.
Binary
logistic
regression
predictive
factors
willingness
have
deprescribed.
All
tests
performed
two-tailed
p
<
0.05
considered
statistically
significant.
Results:
A
total
315
aged
older
completed
questionnaire.
Majority
participants,
83.81%
(95%
CI,
79.72%
87.90%)
stated
that
they
satisfied
their
medications,
would
be
willing
deprescribe
or
more
medications.
Participants
expressed
positive
attitude
toward
pharmacists'
(68.89%,
95%
63.75%
74.03%)
(71.11%,
66.08%
76.14%).
who
specific
preference
likely
show
dissatisfaction
current
greater
Three
found
associated
towards
deprescribing:
low
concerns
about
stopping
factor
score
(aOR
0.54,
CU=0.35–
0.84;
p=0.006),
appropriateness
0.62,
CI=0.39–
0.98;
p=0.039),
opinion
2.35,
CI=1.18–
4.70;
p=
0.016).
Conclusion:
showed
patient's
for
deprescription
pharmacists
being
involved
process.
Results
favour
transition
patient-centred
care
shared-decision
making
model.
Keywords:
patient
preference,
pharmacist,
Drugs & Aging,
Journal Year:
2019,
Volume and Issue:
36(12), P. 1133 - 1139
Published: Sept. 13, 2019
The
objective
of
this
study
was
to
gain
insights
into
the
attitudes
men
with
lower
urinary
tract
symptoms
towards
deprescribing
alpha-blockers
and
assess
their
willingness
participate
in
a
planned
discontinuation
trial.
This
cross-sectional
questionnaire
study.
Men
aged
30
years
older
symptoms,
who
were
first
prescribed
an
alpha-blocker
2015
or
2016,
selected
from
population-based
prescription
database.
We
recorded
symptom
severity
(e.g.,
International
Prostate
Symptom
Score
Overactive
Bladder
questionnaire)
patient
characteristics
comorbidity
polypharmacy).
linguistically
validated
Dutch
version
revised
Patients'
Attitudes
Towards
Deprescribing
(rPATD)
also
used,
which
we
added
ten
specific
questions
on
alpha-blockers.
Information
about
future
trial
then
provided
participants
asked
indicate
if
they
would
participate.
explored
explanatory
factors
for
by
logistic
regression
analyses.
Of
1380
patients
database,
421
using
alpha-blocker,
195
completed
questionnaire.
these,
16
excluded
because
indwelling
catheter
use
unknown
indication.
mean
age
179
69.4
(standard
deviation
9.2)
years.
Most
satisfied
current
therapy,
but
almost
all
(93%)
willing
stop
medicine
at
request
doctor.
Therefore,
most
(61%)
proposed
Willingness
therapy
affected
patients'
perceptions
appropriateness
concerns
stopping
that
therapy.
Although
are
generally
will
Pharmacy,
Journal Year:
2019,
Volume and Issue:
7(3), P. 129 - 129
Published: Sept. 3, 2019
Deprescribing
is
complex
and
multifactorial
with
multiple
approaches
described
in
the
literature.
Internationally,
there
are
guidelines
tools
available
to
aid
clinicians
patients
identify
safely
withdraw
inappropriate
medications,
post
a
shared
decision-making
medicines
optimisation
review.
The
increase
treatments
use
of
single
disease
model
have
led
healthcare
system
geared
towards
prescribing,
deprescribing
often
seen
as
separate
activity.
should
be
part
key
element
ensuring
remain
on
most
appropriate
medications
at
correct
doses
for
them.
Due
nature
polypharmacy,
every
patient
experience
relationship
unique.
individual's
history
must
incorporated
into
patient-centred
medication
review,
order
optimal
through
changes
circumstance
health.
Knowledge
law
recording
important
ensure
consent
adequately
gained
recorded
line
processes
followed
when
initiating
medication.
In
recent
years,
interested
globally,
number
prominent
networks
grown,
creating
crucial
links
both
research
sharing
good
practice.
British Journal of Clinical Pharmacology,
Journal Year:
2020,
Volume and Issue:
87(3), P. 1499 - 1511
Published: Sept. 22, 2020
The
Goal-directed
Medication
Review
Electronic
Decision
Support
System
(G-MEDSS)
assesses
and
reports
a
patient's
goals,
attitudes
to
deprescribing
Drug
Burden
Index
(DBI)
score,
measure
of
cumulative
exposure
anticholinergic
sedative
medications.
This
study
evaluated
the
effect
implementing
G-MEDSS
in
home
medicines
reviews
(HMRs)
on
DBI
clinical
outcomes.A
cluster-randomised
trial
was
performed
across
Australia.
Accredited
pharmacists
were
randomised
into
intervention
(G-MEDSS
with
usual
care
HMR)
or
comparison
groups
(usual
HMR
alone).
Patients
recruited
by
from
those
routinely
referred
general
practitioners
for
HMR.
primary
outcome
proportion
patients
any
reduction
at
3-months
follow-up.
Secondary
outcomes
included
change
continuous
score
3-months,
recommendations
outcomes.There
201
patient
participants
baseline
(n
=
88
intervention,
n
113
comparison),
159
followed-up
63
96
comparison).
not
significantly
different
(intervention
17%,
11%;
adjusted
odds
ratio
1.44,
95%
confidence
interval
0.56-3.80).
Regarding
secondary
outcomes,
there
no
difference
3-months.
However,
report
made
reduce
greater
than
group
37%,
14%;
3.20,
1.50-6.90).
No
changes
observed
outcomes.Implementation
within
did
patients'
3
months
compared
BMC Family Practice,
Journal Year:
2021,
Volume and Issue:
22(1)
Published: June 22, 2021
Abstract
Objectives
Recruiting
general
practitioners
(GPs)
and
their
multimorbid
older
patients
for
trials
is
challenging
multiple
reasons
(e.g.,
high
workload,
limited
mobility).
The
comparability
of
study
participants
important
interpreting
findings.
This
manuscript
describes
the
baseline
characteristics
GPs
participating
in
‘Optimizing
PharmacoTherapy
adults
In
primary
CAre’
(OPTICA)
trial,
a
optimization
pharmacotherapy
adults.
overall
aim
this
was
to
determine
if
OPTICA
trial
are
comparable
real-world
population
Swiss
care.
Design
Analysis
data
from
reference
cohort
FIRE
(‘Family
medicine
ICPC
Research
using
Electronic
medical
records’)
project.
Setting
Primary
care,
Switzerland.
Participants
Three
hundred
twenty-three
(≥
3
chronic
conditions)
with
polypharmacy
5
regular
medications)
aged
≥
65
years
43
recruited
were
compared
22,907
227
database.
Methods
We
other
described
willingness
have
medications
deprescribed
revised
Patients’
Attitudes
Towards
Deprescribing
(rPATD)
questionnaire.
Results
project
similar
terms
sociodemographic
work
as
GP
(e.g.
fifties,
10
experience,
60%
self-employed,
80%
group
practice).
median
age
77
45%
women.
Patients
database
age,
certain
clinical
systolic
blood
pressure,
body
mass
index)
health
services
use
selected
lab
vital
measurements).
More
than
reported
be
willing
stop
1
doctor
said
that
would
possible.
Conclusion
into
relatively
population,
which
indicates
recruiting
generalizable
patient
sample
possible
care
setting.
Multimorbid
deprescribed.
Trial
registration
Clinicaltrials.gov
(
NCT03724539
),
KOFAM
(Swiss
national
portal)
SNCTP000003060
Universal
Number
(U1111-1226-8013)
Patient Preference and Adherence,
Journal Year:
2021,
Volume and Issue:
Volume 15, P. 2197 - 2208
Published: Sept. 1, 2021
Purpose:
To
explore
how
adult
patients
perceive
deprescribing
in
a
country
with
developing
pharmaceutical
care.
Patients
and
Methods:
This
was
multicenter
cross-sectional
study
conducted
ten
community
pharmacies
across
Croatia.
Community-dwelling
adults
40
years
older,
taking
at
least
one
prescription
medication
long
term,
were
invited
to
participate.
The
revised
validated
Patients'
Attitude
Towards
Deprescribing
Questionnaire
used
investigate
community-dwelling
adults'
opinions
on
potential
discontinuation.
Questions
regarding
the
patients'
perception
of
pharmacist
competences
involvement
as
well
preferences
added.
Collected
data
analyzed
using
IBM
SPSS
Statistics
descriptive
inferential
statistical
analysis.
Binary
logistic
regression
predictive
factors
willingness
have
deprescribed.
All
tests
performed
two-tailed
p
<
0.05
considered
statistically
significant.
Results:
A
total
315
aged
older
completed
questionnaire.
Majority
participants,
83.81%
(95%
CI,
79.72%
87.90%)
stated
that
they
satisfied
their
medications,
would
be
willing
deprescribe
or
more
medications.
Participants
expressed
positive
attitude
toward
pharmacists'
(68.89%,
95%
63.75%
74.03%)
(71.11%,
66.08%
76.14%).
who
specific
preference
likely
show
dissatisfaction
current
greater
Three
found
associated
towards
deprescribing:
low
concerns
about
stopping
factor
score
(aOR
0.54,
CU=0.35–
0.84;
p=0.006),
appropriateness
0.62,
CI=0.39–
0.98;
p=0.039),
opinion
2.35,
CI=1.18–
4.70;
p=
0.016).
Conclusion:
showed
patient's
for
deprescription
pharmacists
being
involved
process.
Results
favour
transition
patient-centred
care
shared-decision
making
model.
Keywords:
patient
preference,
pharmacist,
