bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2023,
Volume and Issue:
unknown
Published: Aug. 10, 2023
ABSTRACT
When
faced
with
starvation,
the
bacterium
Bacillus
subtilis
transforms
itself
into
a
dormant
cell
type
called
"spore".
Sporulation
initiates
an
asymmetric
division
event,
which
requires
relocation
of
core
divisome
components
FtsA
and
FtsZ,
after
sigma
factor
σ
F
is
exclusively
activated
in
smaller
daughter
cell.
Compartment
specific
activation
SpoIIE
phosphatase,
displays
biased
localization
on
one
side
septum
associates
structural
protein
DivIVA,
but
mechanism
by
this
preferential
achieved
unclear.
Here,
we
isolated
variant
DivIVA
that
indiscriminately
activates
both
cells
due
to
promiscuous
SpoIIE,
was
corrected
overproduction
FtsZ.
We
propose
unique
feature
sporulation
septum,
defined
machinery,
drives
trigger
initiation
program.
The Plant Cell,
Journal Year:
2024,
Volume and Issue:
36(6), P. 2375 - 2392
Published: March 12, 2024
Abstract
Homeodomain
(HD)
proteins
regulate
embryogenesis
in
animals
such
as
the
fruit
fly
(Drosophila
melanogaster),
often
a
concentration-dependent
manner.
HD-leucine
zipper
(Zip)
IV
family
genes
are
unique
to
plants
and
function
L1
epidermal
cell
layer.
However,
our
understanding
of
roles
HD-Zip
plant
morphogenesis
is
limited.
In
this
study,
we
investigated
tomato
(Solanum
lycopersicum)
multicellular
trichomes,
type
micro-organ
plants.
We
found
that
gradient
regulator
Woolly
(Wo)
coordinates
spatially
polarized
division
expansion
trichomes.
Moreover,
identified
TEOSINTE
BRANCHED1,
CYCLOIDEA,
PROLIFERATING
CELL
NUCLEAR
ANTIGEN
BINDING
FACTOR
(TCP)
transcription
factor-encoding
gene,
SlBRANCHED2a
(SlBRC2a),
key
downstream
target
Wo
regulates
transition
from
expansion.
High
levels
promote
apical
trichome
cells,
whereas
basal
mediates
negative
feedback
loop
with
SlBRC2a
forces
cells
enter
endoreduplication.
The
restricted
high
low
activities
pattern
These
findings
provide
insights
into
functions
during
morphogenesis.
ABSTRACT
Plant
stem
cells,
residing
in
the
shoot
and
root
apical
meristems,
are
fundamental
for
continuous
growth
organ
formation
throughout
plant
life
cycle.
Their
regulation
is
driven
by
convergence
of
endogenous
developmental
cues
exogenous
environmental
signals,
making
them
pivotal
to
overall
development.
Auxin,
a
key
phytohormone,
serves
as
major
internal
signal,
orchestrating
cell
initiation,
maintenance,
differentiation,
adaptation
through
intricate
biosynthesis,
transport,
signaling
networks.
This
review
summarizes
recent
progress
understanding
cellular
molecular
mechanisms
which
auxin
guides
functions
both
meristems.
Through
these
insights,
we
explore
how
plants
utilize
auxin‐driven
pathways
optimize
ever‐changing
environments.
Proceedings of the National Academy of Sciences,
Journal Year:
2024,
Volume and Issue:
121(13)
Published: March 19, 2024
When
faced
with
starvation,
the
bacterium
Bacillus
subtilis
transforms
itself
into
a
dormant
cell
type
called
"spore".
Sporulation
initiates
an
asymmetric
division
event,
which
requires
relocation
of
core
divisome
components
FtsA
and
FtsZ,
after
sigma
factor
σ
F
is
exclusively
activated
in
smaller
daughter
cell.
Compartment-specific
activation
SpoIIE
phosphatase,
displays
biased
localization
on
one
side
septum
associates
structural
protein
DivIVA,
but
mechanism
by
this
preferential
achieved
unclear.
Here,
we
isolated
variant
DivIVA
that
indiscriminately
activates
both
cells
due
to
promiscuous
SpoIIE,
was
corrected
overproduction
FtsZ.
We
propose
redeployed
machinery
drive
trigger
initiation
sporulation
program.
Science Advances,
Journal Year:
2025,
Volume and Issue:
11(6)
Published: Feb. 5, 2025
Cells
sense
and
integrate
multiple
signals
to
coordinate
a
response.
A
receptor-kinase
signaling
pathway
for
plant
stomatal
development
shares
components
with
the
immunity
pathway.
The
mechanism
ensuring
their
signal
specificities
remains
unclear.
Using
chemical
genetics,
here,
we
report
identification
of
small
molecule,
kC9,
that
triggers
excessive
differentiation
by
inhibiting
canonical
ERECTA
kC9
binds
inhibits
downstream
mitogen-activated
protein
kinase
MPK6,
perturbing
its
substrate
interaction.
Notably,
activation
immune
bacterial
flagellin
peptide
nullified
kC9’s
effects
on
development.
This
cross-regulation
depends
receptor
FLS2
(FLAGELLIN
SENSING
2)
occurs
even
in
absence
if
family
population
becomes
suboptimal.
Proliferating
lineage
cells
are
vulnerable
this
penetration.
Our
findings
suggest
specificity
between
can
be
ensured
homeostasis,
reflecting
availability
upstream
receptors,
thereby
providing
an
unanticipated
view
specificity.
Nature Communications,
Journal Year:
2025,
Volume and Issue:
16(1)
Published: March 17, 2025
Abstract
During
development,
many
precursor
lineages
are
flexible,
producing
variable
numbers
and
types
of
progeny
cells.
What
determines
whether
precursors
differentiate
or
continue
dividing?
Here
we
take
a
quantitative
approach
that
combines
long-term
live
imaging,
statistical
modeling
computational
simulations
to
probe
the
developmental
flexibility
stomatal
lineage
ground
cells
(SLGC)
in
Arabidopsis
leaves.
We
discover
cell
size
is
strong
predictor
SLGC
behaviour
linked
division
at
multiple
spatial
scales.
At
neighbourhood
scale,
correlates
with
strength
cell-cell
signaling,
which
affects
rate
SPEECHLESS
(SPCH),
division-promoting
transcription
factor,
degraded.
subcellular
nuclear
size,
modulates
concentration
SPCH
nucleus.
Our
work
shows
how
initial
differences
levels
canalized
by
signaling
inform
flexible
type.
Current Opinion in Plant Biology,
Journal Year:
2024,
Volume and Issue:
79, P. 102530 - 102530
Published: April 16, 2024
Plant
morphogenesis
largely
depends
on
the
orientation
and
rate
of
cell
division
elongation,
their
coordination
at
all
levels
organization.
Despite
recent
progresses
in
comprehension
pathways
controlling
plane
determination
plant
cells,
many
pieces
are
missing
to
puzzle.
For
example,
we
have
a
partial
formation,
function
evolutionary
significance
preprophase
band,
plant-specific
cytoskeletal
array
involved
premitotic
setup
plane,
as
well
role
nucleus
its
connection
band
microtubules.
Likewise,
several
modeling
studies
point
strong
relationship
between
shape
geometry,
but
emergence
such
geometric
rules
from
molecular
cellular
play
still
obscure.
Yet,
imaging
technologies
genetic
tools
hold
lot
promise
tackle
these
challenges
revisit
old
questions
with
unprecedented
resolution
space
time.
Plants,
Journal Year:
2024,
Volume and Issue:
13(13), P. 1824 - 1824
Published: July 3, 2024
Regulation
of
microtubule
dynamics
is
crucial
during
key
developmental
transitions
such
as
gametogenesis,
fertilization,
embryogenesis,
and
seed
formation,
where
cells
undergo
rapid
changes
in
shape
function.
In
plants,
katanin
plays
an
essential
role
dynamics.
This
study
investigates
two
mutants
Arabidopsis
thaliana,
named
elk5-1D
(erecta-like
5,
ELK5)
loo1
(lollipop
1),
which
are
characterized
by
round
seeds,
dwarfism,
fertility
defects.
Notably,
exhibits
a
dominant
inheritance
pattern,
whereas
recessive.
Through
positional
cloning,
we
identified
both
new
alleles
the
KATANIN
1
(KTN1)
gene,
encodes
microtubule-severing
enzyme
critical
for
cell
division
morphology.
Mutations
KTN1
disrupt
embryo
lead
to
emergence
twin
phenotype.
Our
findings
underscore
early
embryonic
development,
potentially
influencing
fate
reproductive
cells.
