Evaluation of whole blood immunoreactivity DOI

I A Seledtsova,

Tatyana Ya. Lyubavskaya,

Anatoly Pyshenko

et al.

Pirogov Russian Journal of Surgery, Journal Year: 2024, Volume and Issue: 12, P. 122 - 122

Published: Jan. 1, 2024

To assess cellular immunoreactivity, lipopolysaccharide (LPS), Concanavalin A (Con A), or LPS together with Con was added to the whole blood for 18 hours. preferentially stimulated release of tumor necrosis factor-alfa (TNF-α), interleukin-6 (IL-6), IL-10 and vascular endothelial growth factor (VEGF) by cells, whereas significantly enhanced secretion interferon-gamma (IFN-gamma) IL-2. Addition heparin slightly decreased IL-2 VEGF, but not other cytokines. This test can be used innate adaptive immunoreactivity may useful in surgical practice preparation components (serum, plasma, leukocyte- platelet-rich plasma) objective immunologic monitoring.

Language: Английский

Androgenetic Alopecia: A Study on The Efficacy of a Combined Protocol of Blue Light Photobiomodulation and Subcutaneous Infiltrations of Biomimetic Peptides DOI
Adone Baroni

Published: July 19, 2024

Androgenetic Alopecia (AGA) is a common condition affecting men and women, characterized by progressive hair follicle miniaturization consequent loss. Blue light Photobiomodulation (PBM) LED (Light emitting diode) device infiltrations of biomimetic peptides therapy are two emerging approaches for AGA treatment. The aim this study was to evaluate the efficacy combined protocol blue PBM on scalp A total 20 patients with diagnosis, according Hamilton-Norwood criteria, were enrolled in study. All treated at same time, both subcutaneous scalp. At 6 months follow-up, significant increase density observed 85% treated. results our suggest that PRP could be an effective treatment AGA. Further clinical studies larger number needed confirm these long-term

Language: Английский

Citations

1
The Impact of Growth Factors in Platelet‐Rich Plasma Combination Therapy for Androgenic Alopecia DOI Creative Commons
Jie Ren,

Jingxuan Sun,

Zheng-Hui Li

et al.

Dermatologic Therapy, Journal Year: 2024, Volume and Issue: 2024(1)

Published: Jan. 1, 2024

The efficacy of platelet‐rich plasma (PRP) therapy for androgenic alopecia (AGA) varies among diverse populations. While prior research has emphasized the pivotal role growth factors as active components in PRP, specific relationship between and treatment outcomes AGA remains unclear. This study aims to explore how PRP is influenced by types concentrations factors. analysis samples from 46 patients involved assessing seven using an enzyme‐linked immunosorbent assay. Patients received a course three treatments along with traditional medicines. assessment conducting trichoscopy tests before after treatment, measuring both hair density (HD) caliber (HC). findings revealed that HD increased 36 patients, positively correlating glial cell‐derived neurotrophic factor (GDNF) concentration ( p = 0.005). In addition, HC 35 demonstrating positive correlation platelet‐derived factor‐BB (PDGF‐BB) < 0.05). Notably, gender‐based identified statistically significant difference increase post‐PRP no correlations were observed demographic changes HD/HC > confirms beneficial influence certain on outcomes. Future should further clarify their mechanisms promoting growth, paving way development novel therapeutic agents.

Language: Английский

Citations

0
Platelet-rich fibrin in dentistry DOI Creative Commons

Ping Song,

Dawei He, Song Ren

et al.

Journal of Applied Biomaterials & Functional Materials, Journal Year: 2024, Volume and Issue: 22

Published: Jan. 1, 2024

Objectives: To review the progress of Platelet Rich Fibrin (PRF) as a biomaterial in dentistry and to highlight its promising application safe biocompatible autologous platelet concentrate. Publications were searched GeenMedical, X-mol, GoogleScholar, PubMed from October 2024 with no language restrictions. The literature was for relevant databases journals on use PRFs up 2024, inclusion criteria included randomized controlled trials, clinical case series, systematic reviews. Conclusion: PRF is second-generation concentrate that sourced oneself, has fewer adverse effects, simple prepare. These materials include growth factors fibrin scaffolds, which are extensively utilized regenerative medicine. By outlining PRF, we found good results can be achieved when used treat these conditions. Clinical significance: widespread, particularly periodontal soft hard tissue regeneration, oral lichen planus, pulpal regeneration. This article reviews background, classification, preparation methods PRFs, along their dental applications. We anticipate further research various derivatives future, will significantly improve utilization applications offer fresh insights diagnosing treating diseases.

Language: Английский

Citations

0
Evaluation of whole blood immunoreactivity DOI

I A Seledtsova,

Tatyana Ya. Lyubavskaya,

Anatoly Pyshenko

et al.

Pirogov Russian Journal of Surgery, Journal Year: 2024, Volume and Issue: 12, P. 122 - 122

Published: Jan. 1, 2024

To assess cellular immunoreactivity, lipopolysaccharide (LPS), Concanavalin A (Con A), or LPS together with Con was added to the whole blood for 18 hours. preferentially stimulated release of tumor necrosis factor-alfa (TNF-α), interleukin-6 (IL-6), IL-10 and vascular endothelial growth factor (VEGF) by cells, whereas significantly enhanced secretion interferon-gamma (IFN-gamma) IL-2. Addition heparin slightly decreased IL-2 VEGF, but not other cytokines. This test can be used innate adaptive immunoreactivity may useful in surgical practice preparation components (serum, plasma, leukocyte- platelet-rich plasma) objective immunologic monitoring.

Language: Английский

Citations

0