Sleep Behaviour in Sickle Cell Disease: A Systematic Review and Meta-Analysis DOI Creative Commons
Melanie Koelbel, Fenella J. Kirkham

Children, Journal Year: 2024, Volume and Issue: 12(1), P. 21 - 21

Published: Dec. 26, 2024

Background/Objectives: There is a high prevalence of sleep behaviour disorders, as well disordered breathing (SDB), in individuals living with sickle cell disease (SCD). SDB has been systematically reviewed; therefore, this systematic review and meta-analysis focused on behaviour. Methods: The comprehensive literature search, following PRISMA reporting guidelines, included all languages, conference proceedings published theses from inception through February 2022. We identified 31 studies, most the research being conducted North America, using polysomnography, actigraphy questionnaires/diaries paediatric SCD cohorts. Results: Total time (TST) decreased, while onset latency (SOL) increased age. TST was higher self-reported diary measures lower polysomnography (PSG) assessments. SOL lowest during PSG highest actigraphy. discrepancy between might be due to overestimation by parents. In six were compared people healthy controls; four, longer those it shorter two. Meta-analyses effect limited publication bias, heterogeneity part related measurement differences. No significant differences found. Conclusions: scarcity case-control studies findings likely attributable variations assessment methodologies. Gaps should addressed.

Language: Английский

Examining Specific Theory-of-Mind Aspects in Amnestic and Non-Amnestic Mild Cognitive Impairment: Their Relationships with Sleep Duration and Cognitive Planning DOI Creative Commons

Areti Batzikosta,

Despina Μoraitou, Paschalis Steiropoulos

et al.

Brain Sciences, Journal Year: 2025, Volume and Issue: 15(1), P. 57 - 57

Published: Jan. 10, 2025

Background/Objectives: The study examined the relationships between specific Theory-of-Mind (ToM) dimensions, cognitive planning, and sleep duration in aging adults. Methods: sample included 179 participants, comprising 46 cognitively healthy individuals, 75 diagnosed with amnestic Mild Cognitive Impairment (aMCI), 58 non-amnestic (naMCI). mean age of participants was 70.23 years (SD = 4.74), a educational attainment 12.35 3.22) gender distribution 53 men 126 women. ToM assessment tasks measuring understanding interpretation non-literal speech, proverbs metaphors, as well an emotion-recognition test. For Tower Test utilized. Sleep measured using actigraphy. Results: We identified significant differences various tasks' performance groups, particularly speech third-order stories. HC group consistently outperformed both MCI groups these tasks, aMCI showing higher than naMCI. Mediation analysis applied to examine potential direct indirect effects on indicated that total time had through planning-mainly rule violation score-on aspects. Hence, besides pathologies especially naMCI, seems also be associated via executive functioning decrements. Conclusions: findings underscore social implications deficits due and/or decrease, naMCI older adults, they can seriously impair their interactions. Targeted interventions could improve emotional understanding, communication, overall quality life.

Language: Английский

Citations

1
Innovations in acute and chronic pain biomarkers: enhancing diagnosis and personalized therapy DOI Creative Commons
Sean Mackey, Nima Aghaeepour, Brice Gaudillière

et al.

Regional Anesthesia & Pain Medicine, Journal Year: 2025, Volume and Issue: 50(2), P. 110 - 120

Published: Feb. 1, 2025

Pain affects millions worldwide, posing significant challenges in diagnosis and treatment. Despite advances understanding pain mechanisms, there remains a critical need for validated biomarkers to enhance diagnosis, prognostication, personalized therapy. This review synthesizes recent advancements identifying validating acute chronic biomarkers, including imaging, molecular, sensory, neurophysiological approaches. We emphasize the emergence of composite, multimodal strategies that integrate psychosocial factors improve precision applicability management. Neuroimaging techniques like MRI positron emission tomography provide insights into structural functional abnormalities related pain, while electrophysiological methods electroencepholography magnetoencepholography assess dysfunctional processing neuroaxis. Molecular cytokines, proteomics, metabolites, offer diagnostic prognostic potential, though extensive validation is needed. Integrating these with clinical practice can revolutionize management by enabling treatment strategies, improving patient outcomes, potentially reducing healthcare costs. Future directions include development composite biomarker signatures, artificial intelligence, signature integration decision support systems. Rigorous standardization efforts are also necessary ensure clinically useful. Large-scale collaborative research will be vital driving progress this field implementing practice. comprehensive highlights potential transform management, offering hope improved personalization, outcomes.

Language: Английский

Citations

1
Objective sleep monitoring at home in older adults: A scoping review DOI Creative Commons
Sarah Nauman Ghazi, Anders Behrens, Jessica Berner

et al.

Journal of Sleep Research, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 9, 2024

Summary Inadequate sleep in older adults is linked to health issues such as frailty, cognitive impairment and cardiovascular disorders. Maintaining regular patterns important for healthy aging, making effective monitoring essential. While polysomnography the gold‐standard diagnosing disorders, its use home settings limited. Alternative objective methods can offer insights into natural factors affecting them without limitations of polysomnography. This scoping review aims examine current technologies, sensors parameters used home‐based adults. It also explore various predictors outcomes associated with understand at home. We identified 54 relevant articles using PubMed, Scopus, Web Science an AI tool (Research Rabbit), 48 studies wearable technologies eight non‐wearable technologies. Further, six types were utilized. The most common technology employed was actigraphy wearables, while ballistocardiography electroencephalography less common. frequent measured total time, wakeup after onset efficiency, only evaluating architecture terms stages. Additionally, categories analysed, including Health‐related, Environmental, Interventional, Behavioural, Time Place, Social associations. These associations correlate include in‐bed behaviours, exterior housing conditions, aerobic exercise, living place, relationship status, seasonal thermal environments.

Language: Английский

Citations

3
The daily reciprocal associations between electroencephalography measured sleep and affect DOI Creative Commons
M. E. Boon, Mahdad Jafarzadeh Esfahani, Jacqueline M. Vink

et al.

Journal of Sleep Research, Journal Year: 2024, Volume and Issue: unknown

Published: June 6, 2024

Summary Self‐report studies show that sleep and positive negative affect are closely bidirectionally linked. However, assessing objectively yield more inconsistent results. This study assessed the reciprocal, daily relationship between as measured with electroencephalography (EEG) (measured in evening) a natural setting. We both on macrolevel (i.e., rapid eye movement [REM] slow‐wave [SWS] duration) microlevel REM fragmentation). In this study, 33 participants healthy college students, mean [standard deviation] age 21.55 [3.73] years, 67% female) were followed for 2 weeks. Each participant wore an EEG headband 15 nights had polysomnography during 3 of providing 72 analysable 271 headband. Every evening reported their momentary affect. examined pre‐sleep variables, well reverse relationship, variables predicting next day. detected higher was related to fragmented sleep. result only found not No significant associations time spent SWS. Overall, no support reciprocal association Only limited one direction associated fragmentation at night).

Language: Английский

Citations

1
Associations between Aircraft Noise, Sleep, and Sleep–Wake Cycle: Actimetric Data from the UK Biobank Cohort near Four Major Airports DOI Creative Commons
Xiangpu Gong,

Katie Eminson,

Glory Atilola

et al.

Environmental Health Perspectives, Journal Year: 2024, Volume and Issue: 132(9)

Published: Sept. 1, 2024

Nighttime aircraft noise may affect people's sleep, yet large-scale evidence using objective and subjective measures remains limited.

Language: Английский

Citations

0
Long-term self-supervised learning for accelerometer-based sleep–wake recognition DOI Creative Commons
Aleksej Logacjov, Kerstin Bach, Paul Jarle Mork

et al.

Engineering Applications of Artificial Intelligence, Journal Year: 2024, Volume and Issue: 141, P. 109758 - 109758

Published: Dec. 6, 2024

Language: Английский

Citations

0
Sleep Behaviour in Sickle Cell Disease: A Systematic Review and Meta-Analysis DOI Creative Commons
Melanie Koelbel, Fenella J. Kirkham

Children, Journal Year: 2024, Volume and Issue: 12(1), P. 21 - 21

Published: Dec. 26, 2024

Background/Objectives: There is a high prevalence of sleep behaviour disorders, as well disordered breathing (SDB), in individuals living with sickle cell disease (SCD). SDB has been systematically reviewed; therefore, this systematic review and meta-analysis focused on behaviour. Methods: The comprehensive literature search, following PRISMA reporting guidelines, included all languages, conference proceedings published theses from inception through February 2022. We identified 31 studies, most the research being conducted North America, using polysomnography, actigraphy questionnaires/diaries paediatric SCD cohorts. Results: Total time (TST) decreased, while onset latency (SOL) increased age. TST was higher self-reported diary measures lower polysomnography (PSG) assessments. SOL lowest during PSG highest actigraphy. discrepancy between might be due to overestimation by parents. In six were compared people healthy controls; four, longer those it shorter two. Meta-analyses effect limited publication bias, heterogeneity part related measurement differences. No significant differences found. Conclusions: scarcity case-control studies findings likely attributable variations assessment methodologies. Gaps should addressed.

Language: Английский

Citations

0