Hypoalbuminaemia and its association with disease and clinical outcomes in cats DOI Creative Commons

Karen Fong,

Ioannis L. Oikonomidis, Derek Leong

et al.

Journal of Small Animal Practice, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 3, 2024

Objectives To report the incidence of feline hypoalbuminaemia and characterise distribution presenting disease categories pathoaetiologies in cats. The secondary aim was to evaluate relationship between clinical outcomes. Materials Methods Medical records cats with (<28.0 g/L, reference interval: 28.0 39.0 g/L) a veterinary teaching hospital over 5 years were retrospectively reviewed. severity further stratified into mild (24.0 27.9 g/L), moderate (20.0 23.9 severe (≤19.9 groups. median albumin groups compared determined categories, Results 32.7% (533/1632). Gastrointestinal most common category associated [154/533 (28.9%)], which, 49.4% (76/154) had gastrointestinal neoplasia. Neoplastic [159/533 (29.8%)] inflammatory conditions [158/533 (29.6%)] noted. Statistically significant differences serum individual pathoaetiological found. Cats statistically significantly longer hospitalisation period, cost treatment increased odds death (odds ratio 2.4, 95% confidence 1.3 4.6 3.2, 1.5 6.6, respectively). Clinical Significance our study surpasses previous canine reports. Our findings support as negative acute phase protein cats, frequently disease. Hypoalbuminaemia also features prominently neoplasia, indicating careful appraisal presence protein‐losing enteropathy is required these cases. Finally, found be prognostic indicator this study.

Language: Английский

Single large enterolith in a cat with chronic inflammatory enteropathy DOI Creative Commons

P.S.P. Thong,

Guy Wolfenden,

Takanori Sugiyama

et al.

Veterinary Record Case Reports, Journal Year: 2024, Volume and Issue: 12(2)

Published: Feb. 13, 2024

Abstract A 3‐year‐old, male, neutered, domestic shorthair cat with a history of chronic intermittent vomiting, diarrhoea and constipation was referred for abdominal ultrasound mid‐abdominal mass identified on palpation. Findings included densely shadowing structure within the distal ileum severe local muscularis thickening, mild diffuse small intestinal an enlarged right ileocolic lymph node. Abdominal radiographs showed to be most consistent enterolith. Enterolithiasis is rare condition in companion animals, but common horses selected populations human patients. Enterectomy performed, histopathology results biopsies were inflammatory enteropathy. Chemical analysis enterolith revealed predominantly calcium phosphate composition. At 3‐month follow‐up, had gained weight marked improvement gastrointestinal signs. Screening underlying structural disease may beneficial cats diagnosed enteroliths.

Language: Английский

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Візуальна діагностика за патології підшлункової залози у котів DOI Creative Commons

Ю. Ф. Дереза,

Н. С. Канівець

Scientific Progress & Innovations, Journal Year: 2024, Volume and Issue: 27(1), P. 162 - 166

Published: March 29, 2024

Патології підшлункової залози є досить поширеними захворюваннями у свійських котів, зокрема запалення залози. Вчасна діагностика дозволяє обрати оптимальний метод лікування тварини, що визначає актуальність досліджень цій сфері. Метою роботи обґрунтування інформативності різних неінвазивних методів діагностики панкреатиту котів. У обстеженні котів використано загальноклінічні (огляд, пальпація, термометрія, аускультація тощо), рентгенографічні та ультра- сонографічні методи дослідження. статті наведено результати дослідження хворих на панкреатит різного віку (від 1 до 15 років), порід (безпорідні, сіамська, орієнтал, шотландська висловуха), статі (кіт, кішка). Встановлено, характерними ознаками захворювання були дегідратація (83 %), ано-/гіпорексія (87,5 виснаження (84 блювання (75 болючість черева (65 %). За умови ультасонографічного виявлено нерівномірно потовщену гіпоехогенну підшлункову залозу оточену значної кількості тварин рідиною гіпоехогенної щільності, стінка дванадцятипалої кишки дотична була потовщеною, складчастою. результатами ультрасонографії складно диференціювати гострий хронічний оскільки наявність гіперехогенності паренхіми вказує фіброз її тканини і спостерігалася за наявності хронічного панкреатиту, але не часто. рентгенографії змін в органах черевної порожнини, або втрат їх архітектоніки виявлено, дозволило виключити окремі причини розладів шлунково-кишкового тракту. Практичне значення полягає отриманні нових наукових знань щодо розвитку залежно від перебігу захворювання, моніторингу стану тварин, перспектив наданні переваг при лікуванні разі його ускладнення.

Citations

0

The Importance of Intestinal Microbiota and Dysbiosis in the Context of the Development of Intestinal Lymphoma in Dogs and Cats DOI Open Access
Wioleta Jadwiga Breczko, Joanna Bubak, Marta Miszczak

et al.

Cancers, Journal Year: 2024, Volume and Issue: 16(12), P. 2255 - 2255

Published: June 18, 2024

Recent advancements have significantly enhanced our understanding of the crucial role animal microbiomes play in veterinary medicine. Their importance complex intestinal environment spans immune modulation, metabolic homeostasis, and pathogenesis chronic diseases. Dysbiosis, a microbial imbalance, can lead to range diseases affecting both individual organs entire organism. Microbial disruption triggers inflammatory responses mucosa disturbs increasing susceptibility toxins their metabolites. These dynamics contribute development lymphoma, necessitating rigorous investigation into microbiota tumorigenesis. The principles explored this study extend beyond medicine encompass broader human health concerns. There are remarkable parallels between subtypes lymphoproliferative disorders animals humans, particularly Hodgkin’s lymphoma non-Hodgkin’s lymphoma. Understanding etiology cancer lymphatic system formation is critical for developing preventive strategies therapeutic interventions, with potential improve patient outcomes. aim discuss optimal composition microbiome dogs cats alterations during lesions, Molecular cellular analyses also incorporated detect changes carcinogenesis. A review literature on connections gut lymphomas presented, along diagnostic approaches these cancers.

Language: Английский

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0

MicroRNA as Biomarkers in Small Animal Gastrointestinal Inflammation and Cancer DOI Creative Commons
Janne G. Lyngby, Lise N. Nielsen

Advances in Small Animal Care, Journal Year: 2024, Volume and Issue: 5(1), P. 109 - 119

Published: Aug. 7, 2024

Gastrointestinal (GI) disease is common in companion animals. Extensive diagnostics are required for the differentiation between GI cancer and chronic inflammatory enteropathy. This diagnostic work-up cost-prohibitive potentially invasive. However, reaching a final diagnosis to initiate appropriate therapeutic intervention improve patient outcome imperative. Thus, there great need biomarkers. One could be microRNAs, as they promising MicroRNAs small RNAs involved with post-transcriptional gene regulation health disease. In both dogs cats, microRNA expression tissue, serum, feces has been investigated biomarkers

Language: Английский

Citations

0

Hypoalbuminaemia and its association with disease and clinical outcomes in cats DOI Creative Commons

Karen Fong,

Ioannis L. Oikonomidis, Derek Leong

et al.

Journal of Small Animal Practice, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 3, 2024

Objectives To report the incidence of feline hypoalbuminaemia and characterise distribution presenting disease categories pathoaetiologies in cats. The secondary aim was to evaluate relationship between clinical outcomes. Materials Methods Medical records cats with (<28.0 g/L, reference interval: 28.0 39.0 g/L) a veterinary teaching hospital over 5 years were retrospectively reviewed. severity further stratified into mild (24.0 27.9 g/L), moderate (20.0 23.9 severe (≤19.9 groups. median albumin groups compared determined categories, Results 32.7% (533/1632). Gastrointestinal most common category associated [154/533 (28.9%)], which, 49.4% (76/154) had gastrointestinal neoplasia. Neoplastic [159/533 (29.8%)] inflammatory conditions [158/533 (29.6%)] noted. Statistically significant differences serum individual pathoaetiological found. Cats statistically significantly longer hospitalisation period, cost treatment increased odds death (odds ratio 2.4, 95% confidence 1.3 4.6 3.2, 1.5 6.6, respectively). Clinical Significance our study surpasses previous canine reports. Our findings support as negative acute phase protein cats, frequently disease. Hypoalbuminaemia also features prominently neoplasia, indicating careful appraisal presence protein‐losing enteropathy is required these cases. Finally, found be prognostic indicator this study.

Language: Английский

Citations

0