Longitudinal study ofChlamydia pecorumin a healthy Swiss cattle population DOI Creative Commons

Samuel Loehrer,

Fabian Hagenbuch,

Hanna Marti

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Sept. 24, 2023

Abstract Chlamydia pecorum is a globally endemic livestock pathogen but prevalence data from Switzerland has so far been limited. The present longitudinal study aimed to get an insight into the C. in Swiss cattle and investigated infection dynamics. population consisted of bovine herd (n = 308) located on farm north-eastern part Switzerland. comprised dairy cows, beef calves all sampled up five times over one-year period. At each sampling timepoint, rectal conjunctival swabs were collected resulting 782 samples per localization (total n 1564). Chlamydiaceae screening was performed initially, followed by -specific real-time qPCR samples. For -positive samples, bacterial loads determined. During this study, only chlamydial species found. Animal prevalences included 5.2%-11.4%, 38.1%-61.5% 55%-100% calves, respectively. In categories, number higher 151) compared 65), however, average load higher. younger age, mean significantly Of bovines, 9.4% (29/308) high shedders (number copies µl >1000). Calves, which tested positive multiple times, either failed eliminate between timepoints or reinfected, whereas cows mostly at one timepoint. conclusion, found healthy cattle. Our observations suggested that takes place early age immunity might develop time. Although gastrointestinal tract supposed be main site, not cows.

Language: Английский

Current management practices do not adequately safeguard endangered plant species in conservation collections DOI Creative Commons
Zoe Diaz‐Martin, Jeremie B. Fant, Kayri Havens

et al.

Biological Conservation, Journal Year: 2023, Volume and Issue: 280, P. 109955 - 109955

Published: Feb. 16, 2023

Imperiled plant species can benefit from ex situ cultivation to safeguard against loss of genetic diversity and possible extinction in the wild. Few studies use monitoring endangered evaluate how well current management practices maintain limit inbreeding relatedness after plants are brought into cultivation. We examine this question using Attalea crassispatha, a palm with fewer than 100 palms surviving worldwide, only 25 remaining their native habitat. sampled all accessible (both situ) (1) investigate garden collections capture diversity, (2) is carried forward subsequent generations situ, (3) determine number wild founding individuals contributing breeding efforts, (4) identify optimal pairs that would maximize inbreeding. found higher propagation lead self-fertilization population therefore fail adequately steward conservation collection. Using analyses, we identified at different locations, highlighting need for coordinated efforts situ. also putative A. crassispatha genetically unrelated rest study cohort likely mislabeled. This highlights utility importance careful coordination record keeping within among ensure maintained future efforts.

Language: Английский

Citations

16
The estimation of additive genetic variance of body size in a wild passerine is sensitive to the method used to estimate relatedness among the individuals DOI Creative Commons
Mónika Jablonszky, David Cañal, Gergely Hegyi

et al.

Ecology and Evolution, Journal Year: 2024, Volume and Issue: 14(2)

Published: Feb. 1, 2024

Abstract Assessing additive genetic variance is a crucial step in predicting the evolutionary response of target trait. However, estimated may be sensitive to methodology used, e.g., way relatedness assessed among individuals, especially wild populations where social pedigrees can inaccurate. To investigate this possibility, we investigated tarsus length, major proxy skeletal body size birds. The model species was collared flycatcher ( Ficedula albicollis ), socially monogamous but genetically polygamous migratory passerine. We used two matrices estimate variance: (1) based solely on links and (2) similarity matrix large array single‐nucleotide polymorphisms (SNPs). Depending considered, found moderate high heritability estimates for length. In particular, were higher when obtained with instead pedigree. Our results confirm potential trait respond selection highlight methodological concerns calculating phenotypic traits. conclude that using pedigree individuals population significantly deflate variation.

Language: Английский

Citations

3
Adaptive potential in the face of a transmissible cancer in Tasmanian devils DOI Creative Commons
Kasha Strickland, Menna E. Jones, Andrew Storfer

et al.

Published: April 9, 2024

Emerging infectious diseases (EIDs) cause catastrophic declines in wildlife populations, but 2 also generate selective pressures that may result rapid evolutionary responses. One such EID 3 is devil facial tumour disease (DFTD) the Tasmanian devil. DFTD almost always fatal, 4 which likely causes strong selection for traits reduce susceptibility to disease, 5 population decline has left devils vulnerable inbreeding depression. We 6 analysed 22 years of data from an ongoing study a on 7 Freycinet Peninsula, Tasmania, (1) identify whether be causing 8 body size, by estimating phenotypic and genetic correlations between size traits, (2) 9 estimate additive variance DFTD, (3) investigate 10 or were under found positive 11 relationship head width this was not 12 underpinned correlation. Conversely, we negative 13 weight there evidence 14 correlation weight. There 15 weight, no 16 depression any these traits. These results suggest have 17 potential respond adaptively although realised response will 18 critically depend evolution itself.

Language: Английский

Citations

1
Adaptive potential in the face of a transmissible cancer in Tasmanian devils DOI Creative Commons
Kasha Strickland, Menna E. Jones, Andrew Storfer

et al.

Molecular Ecology, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 28, 2024

Abstract Emerging infectious diseases (EIDs) not only cause catastrophic declines in wildlife populations but also generate selective pressures that may result rapid evolutionary responses. One such EID is devil facial tumour disease (DFTD) the Tasmanian devil. DFTD almost always fatal and has reduced average lifespan of individuals by around 2 years, likely causing strong selection for traits reduce susceptibility to disease, population decline left devils vulnerable inbreeding depression. We analysed 22 years data from an ongoing study a on Freycinet Peninsula, Tasmania, (1) identify whether be body size, estimating phenotypic genetic correlations between size traits, (2) estimate additive variance DFTD, (3) investigate or were under found positive relationship head width this was underpinned correlation. Conversely, we negative weight there evidence correlation weight. There weight, no depression any these traits. These results suggest have potential respond adaptively although realised response will critically further depend evolution itself.

Language: Английский

Citations

1
Susceptibility to a sexually transmitted disease in a wild koala population shows heritable genetic variance but no inbreeding depression DOI
Romane Cristescu, Kasha Strickland, Anthony Schultz

et al.

Molecular Ecology, Journal Year: 2022, Volume and Issue: 31(21), P. 5455 - 5467

Published: Aug. 31, 2022

The koala, one of the most iconic Australian wildlife species, is facing several concomitant threats that are driving population declines. Some well known and have clear methods prevention (e.g., habitat loss can be reduced with stronger land-clearing control), whereas others less easily addressed. One major current to koalas chlamydial disease, which impacts on individual survival reproduction rates translate into Effective management strategies for disease in wild currently lacking, and, date, we know little about determinants susceptibility disease. Here, investigated genetic basis variation chlamydia using intensively studied koala populations. We combined data from veterinary examinations, testing, sampling movement monitoring. Out our sample 342 koalas, 60 were found chlamydia. Using genotype information 5007 SNPs investigate role determining status, no evidence inbreeding depression, but a heritability 0.11 (95% CI: 0.06-0.23) probability had Heritability could relevant future management, as it suggests adaptive potential population.

Language: Английский

Citations

7
Longitudinal study of Chlamydia pecorum in a healthy Swiss cattle population DOI Creative Commons

Samuel Loehrer,

Fabian Hagenbuch,

Hanna Marti

et al.

PLoS ONE, Journal Year: 2023, Volume and Issue: 18(12), P. e0292509 - e0292509

Published: Dec. 11, 2023

Chlamydia pecorum is a globally endemic livestock pathogen but prevalence data from Switzerland has so far been limited. The present longitudinal study aimed to get an insight into the C . in Swiss cattle and investigated infection dynamics. population consisted of bovine herd (n = 308) located on farm north-eastern part Switzerland. comprised dairy cows, beef calves all sampled up five times over one-year period. At each sampling timepoint, rectal conjunctival swabs were collected resulting 782 samples per area (total n 1564). Chlamydiaceae screening was performed initially, followed by -specific real-time qPCR samples. For -positive samples, bacterial loads determined. In this study, only chlamydial species found. Animal prevalences determined be 5.2–11.4%, 38.1–61.5% 55–100% calves, respectively. categories, number higher 151) compared 65), however, average load higher. younger age, mean significantly Of bovines, 9.4% (29/308) high shedders (number copies μl >1,000). Calves, which tested positive multiple times, either failed eliminate between timepoints or reinfected, whereas cows mostly at one timepoint. conclusion, found healthy cattle. Our observations suggested that takes place early age immunity might develop time. Although gastrointestinal tract supposed main site, not cows.

Language: Английский

Citations

3
Longitudinal study ofChlamydia pecorumin a healthy Swiss cattle population DOI Creative Commons

Samuel Loehrer,

Fabian Hagenbuch,

Hanna Marti

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Sept. 24, 2023

Abstract Chlamydia pecorum is a globally endemic livestock pathogen but prevalence data from Switzerland has so far been limited. The present longitudinal study aimed to get an insight into the C. in Swiss cattle and investigated infection dynamics. population consisted of bovine herd (n = 308) located on farm north-eastern part Switzerland. comprised dairy cows, beef calves all sampled up five times over one-year period. At each sampling timepoint, rectal conjunctival swabs were collected resulting 782 samples per localization (total n 1564). Chlamydiaceae screening was performed initially, followed by -specific real-time qPCR samples. For -positive samples, bacterial loads determined. During this study, only chlamydial species found. Animal prevalences included 5.2%-11.4%, 38.1%-61.5% 55%-100% calves, respectively. In categories, number higher 151) compared 65), however, average load higher. younger age, mean significantly Of bovines, 9.4% (29/308) high shedders (number copies µl >1000). Calves, which tested positive multiple times, either failed eliminate between timepoints or reinfected, whereas cows mostly at one timepoint. conclusion, found healthy cattle. Our observations suggested that takes place early age immunity might develop time. Although gastrointestinal tract supposed be main site, not cows.

Language: Английский

Citations

0