Viral- and fungal-mediated behavioral manipulation of hosts: summit disease DOI Creative Commons

Abolfazl Masoudi,

Ross Joseph, Nemat O. Keyhani

et al.

Applied Microbiology and Biotechnology, Journal Year: 2024, Volume and Issue: 108(1)

Published: Oct. 23, 2024

Summit disease, in which infected hosts seek heights (gravitropism), first noted modern times by nineteenth-century naturalists, has been shown to be induced disparate pathogens ranging from viruses fungi. Infection results dramatic changes normal activity patterns, and such parasite manipulation of host behaviors suggests a strong selection for convergent outcomes albeit evolved via widely divergent mechanisms. The two best-studied examples involve subset viral fungal insects that induce "summiting" hosts. Summiting presumably functions as means increasing the dispersal pathogen, thus significantly fitness. Here, we review current advances our understanding viral- fungal-induced summit disease behavioral involved. Viral genes implicated this process include hormone-targeting ecdysteroid UDP-glucosyltransferase (apparently essential mediating some but not all) protein tyrosine phosphatase, with light dependance implicated. For disease-causing fungi, though much remains obscure, targeting molting, circadian rhythms, sleep, responses patterns appear Targeting neuronal pathways summit-inducing fungi also appears production effector molecules secondary metabolites affect muscular, immune, and/or neurological processes. It is hypothesized brain structures, particularly Mushroom Bodies (no relation fungus itself), important olfactory association learning control locomotor activity, are critical targets summiting during infection. This phenomenon expands diversity microbial pathogen-interactions dynamics. KEY POINTS: • or height seeking (gravitropism) manipulating insect increase pathogen dispersal. Insect baculoviruses select exhibit evolution use molecular Targets affecting behavior hormones, feeding, locomotion, circadian, pathways.

Language: Английский

Microbial artists: the role of parasite microbiomes in explaining colour polymorphism among amphipods and potential link to host manipulation DOI Creative Commons
Célia Koellsch, Robert Poulin, Priscila M. Salloum

et al.

Journal of Evolutionary Biology, Journal Year: 2024, Volume and Issue: 37(9), P. 1009 - 1022

Published: July 11, 2024

Abstract Parasite infections are increasingly reported to change the microbiome of parasitized hosts, while parasites bring their own microbes what can be a multi-dimensional interaction. For instance, recent hypothesis suggests that microbial communities harboured by may play role in well-documented ability many manipulate host phenotype, and explain why degree which phenotype is altered varies among conspecific parasites. Here, we explored whether microbiomes both hosts associated with variation manipulation Using colour quantification methods applied digital images, investigated uninfected Transorchestia serrulata amphipods, as well amphipods infected Plagiorhynchus allisonae acanthocephalans dilepidid cestode. We then characterized bacteriota amphipod parasites, looking for correlations between bacterial taxa found large colours, weak support direct impact on hosts. Conversely, most interestingly, parasite’s was more strongly correlated potential amphipod-associated bacteria well. Some have synthesize pigments, propose they interact determination amphipods. This study provides correlational an association evolution host–parasite interactions generally.

Language: Английский

Citations

1
Viral- and fungal-mediated behavioral manipulation of hosts: summit disease DOI Creative Commons

Abolfazl Masoudi,

Ross Joseph, Nemat O. Keyhani

et al.

Applied Microbiology and Biotechnology, Journal Year: 2024, Volume and Issue: 108(1)

Published: Oct. 23, 2024

Summit disease, in which infected hosts seek heights (gravitropism), first noted modern times by nineteenth-century naturalists, has been shown to be induced disparate pathogens ranging from viruses fungi. Infection results dramatic changes normal activity patterns, and such parasite manipulation of host behaviors suggests a strong selection for convergent outcomes albeit evolved via widely divergent mechanisms. The two best-studied examples involve subset viral fungal insects that induce "summiting" hosts. Summiting presumably functions as means increasing the dispersal pathogen, thus significantly fitness. Here, we review current advances our understanding viral- fungal-induced summit disease behavioral involved. Viral genes implicated this process include hormone-targeting ecdysteroid UDP-glucosyltransferase (apparently essential mediating some but not all) protein tyrosine phosphatase, with light dependance implicated. For disease-causing fungi, though much remains obscure, targeting molting, circadian rhythms, sleep, responses patterns appear Targeting neuronal pathways summit-inducing fungi also appears production effector molecules secondary metabolites affect muscular, immune, and/or neurological processes. It is hypothesized brain structures, particularly Mushroom Bodies (no relation fungus itself), important olfactory association learning control locomotor activity, are critical targets summiting during infection. This phenomenon expands diversity microbial pathogen-interactions dynamics. KEY POINTS: • or height seeking (gravitropism) manipulating insect increase pathogen dispersal. Insect baculoviruses select exhibit evolution use molecular Targets affecting behavior hormones, feeding, locomotion, circadian, pathways.

Language: Английский

Citations

1