Fish Evo‐Devo: Moving Toward Species‐Specific and Knowledge‐Based Interactome

Journal of Experimental Zoology Part B Molecular and Developmental Evolution, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 27, 2025

ABSTRACT A knowledge‐based interactome maps interactions among proteins and molecules within a cell using experimental data, computational predictions, literature mining. These interactomes are vital for understanding cellular functions, pathways, the evolutionary conservation of protein interactions. They reveal how regulate growth, differentiation, development. Transitioning to functionally validated is crucial in developmental biology (Evo‐Devo), especially non‐model species, uncover unique regulatory networks, novelties, reliable gene interaction models. This enhances our complex trait evolution across species. The European Evo‐Devo 2024 conference Helsinki hosted first fish‐specific symposium, highlighting growing interest fish Advances genome annotation, editing, imaging, molecular screening expanding research. High‐throughput data have enabled deduction networks. next steps involve creating species‐specific interactomes, validating them functionally, integrating additional deepen Evo‐Devo. short review aims address logical this transition, as well necessities limitations journey.

Language: Английский

Navigating the Cold: Integrative Transcriptome Sequencing Approach Reveals Ionoregulatory and Whole-Body Responses to Cold Acclimation in Drosophila ananassae

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: July 22, 2024

Abstract Understanding how species adapt to changing environments is a major goal in evolutionary biology and can elucidate the impact of climate change. Climate imposes inevitable effects on geographical distribution insects as their body temperature primarily depends environment. The vinegar fly Drosophila ananassae expanded from its tropical ancestral range more temperate regions, which requires adaptation colder temperatures. Transcriptome genome-wide association studies focusing ancestral-range population identified targets selection related ionoregulatory tissues. However, cosmopolitan D. adapted environments, where low temperatures last longer, still unknown. Here, we present study effect long-term cold exposure , examining gene expression variation whole tissues, namely hindgut Malpighian tubule. To molecular mechanisms during expansion, included cold-tolerant cold-sensitive strains derived range. We show that acclimation improves tolerance results differential than half transcriptome tissues body. Notably, provide complementary insight into processes at four levels: strains, populations, phenotypes, By determining biochemical pathways phenotypic plasticity underlying tolerance, our enhance understanding environmental changes affect thermal natural populations.

Language: Английский

The Updated Genome of the Burying Beetle Nicrophorus vespilloides, a Model Species for Evolutionary and Genetic Studies of Parental Care

Ecology and Evolution, Journal Year: 2024, Volume and Issue: 14(12)

Published: Dec. 1, 2024

Understanding the evolution of social behavior requires establishing links between genomes and phenotypes. High quality genomic resources from a diverse set species are required for both broad scale comparative analyses targeted functional experiments therefore crucial this goal. Here, we report on an updated genome burying beetle

Language: Английский