Obesity in South and Southeast Asia—A new consensus on care and management

Obesity Reviews, Journal Year: 2022, Volume and Issue: 24(2)

Published: Dec. 1, 2022

Obesity is a chronic disease in which the abnormal or excessive accumulation of body fat leads to impaired health and increased risk mortality complications. Prevalence obesity rising rapidly South Southeast Asia, with potentially serious consequences for local economies, healthcare systems, quality life. Our group specialists from Bangladesh, Brunei Darussalam, India, Indonesia, Malaysia, Philippines, Singapore, Sri Lanka, Thailand, Viet Nam undertook develop consensus recommendations management care adults children Asia. To this end, we identified researched 12 clinical questions related obesity. These address optimal approaches identifying staging obesity, treatment (lifestyle, behavioral, pharmacologic, surgical options) maintenance reduced weight, as well issues weight stigma patient engagement setting. We achieved on 42 that these questions. An algorithm describing presented, keyed various recommendations.

Language: Английский

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Metabolic syndrome

Nature Reviews Disease Primers, Journal Year: 2024, Volume and Issue: 10(1)

Published: Oct. 17, 2024

Language: Английский

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Preconception malnutrition among women and girls in south Asia: prevalence, determinants, and association with pregnancy and birth outcomes

The Lancet Regional Health - Southeast Asia, Journal Year: 2025, Volume and Issue: unknown, P. 100573 - 100573

Published: April 1, 2025

Language: Английский

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Global, regional, and national burden and trends analysis of gallbladder and biliary tract cancer from 1990 to 2019 and predictions to 2030: a systematic analysis for the Global Burden of Disease Study 2019

Frontiers in Medicine, Journal Year: 2024, Volume and Issue: 11

Published: April 4, 2024

Objectives Our aim was to explore the disease burden caused by gallbladder and biliary tract cancer globally, regionally, nationally, age sex. Methods The absolute number of cases age-standardized rates (ASR) incidence, prevalence, mortality, disability-adjusted life years (DALYs) due were extracted from Global Burden Disease (GBD) Study 2019. We estimated trends in calculating percentage change annual (EAPC) ASR, social development index (SDI), region, nation, sex, age. Results From 1990 2019, incident cases, prevalent deaths, DALYs worldwide significantly increased 1.85-fold, 1.92-fold, 1.82-fold, 1.68-fold, respectively. However, tend decrease globally over time. Nevertheless, heterogeneous patterns exist between geographic regions different geographical risk factors, distinct epidemiologically predominant subtypes, potential genetic predispositions or ethnicity. Additionally, socioeconomic status mediates regional variation burden, with increasing SDI HDI scores associated downward DALYs. Older individuals females are at higher cancer, but early-onset is a cause for concern, especially those living lower areas males. High BMI primary factors underlying accounted 15.2% deaths 15.7% Conclusion study comprehensively elucidated distribution dynamic past three decades, multiple dimensions. These findings emphasize importance promoting healthy lifestyle as population-level prevention strategy tailoring control actions based on localized epidemic profiles anatomical subtype.

Language: Английский

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The role of adipokines and ghrelin in interactions and clinical implications in childhood obesity

Journal of Education and Health Promotion, Journal Year: 2024, Volume and Issue: 13(1)

Published: Jan. 1, 2024

BACKGROUND: Childhood obesity is a growing global health concern, especially prevalent in the Arabian Peninsula, and known to contribute metabolic syndrome insulin resistance. This study aimed investigate interplay between adipokines (leptin adiponectin), ghrelin, homeostasis childhood obesity. MATERIAL AND METHODS: A case–control was conducted Babylon involving 120 children/adolescents (7–17 years). The participants were divided into two groups: 60 obese healthy controls. Anthropometric biochemical measures examined, applying World Health Organization (WHO) growth standards categorize weight status. Data on blood lipids, glucose, adipokines, ghrelin collected (Merjan Medical City), ensuring accuracy providing insights pediatric obesity’s hormonal RESULT: Clinical, anthropometric, laboratory attributes of children evaluated, with classification as normal-weight or based BMI/Z-score Waist Circumference. group exhibited elevated triglycerides levels, well reduced adiponectin levels ( P ≤ 0.001). Leptin showed positive correlation (r = 0.352, 0.006). diagnostic model demonstrated significant capacity leptin (AUC > 99%) its importance predicting Each unit increase probability by factor 1.197 (95% CI: 1.0507–1.3632, 0.0068). CONCLUSION: revealed differences clinical, biochemical, biological markers research groups control group. emerged predictor obesity, demonstrating high accuracy. complex interactions among these underscore necessity for comprehensive management strategies.

Language: Английский

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ACTION APAC: Understanding perceptions, attitudes and behaviours in obesity and its management across south and Southeast Asia

Clinical Obesity, Journal Year: 2024, Volume and Issue: 14(3)

Published: Feb. 8, 2024

Summary To identify perceptions and attitudes among people with obesity (PwO) healthcare professionals (HCPs) toward its management in nine Asia‐Pacific (APAC) countries, a cross‐sectional online survey was conducted adult PwO self‐reported body mass index of ≥25 kg/m 2 (≥27 , Singapore), HCPs involved direct patient care. In total, 10 429 1901 completed the survey. Most (68%) (84%) agreed that is disease; however, significant proportion (63%) (41%) believed weight loss complete responsibility only 43% discussed an HCP prior 5 years. respondents acknowledged would be extremely beneficial to PwO's overall health (PwO 76%, 85%), although nearly half (45%) misperceived themselves as overweight or normal weight. Obesity perceived by (58%) (53%) negatively impact forming romantic relationships. cited PwOs' lack interest poor motivation (37%) lose top reasons for not discussing (65%) preferred lifestyle changes over medications exercise unhealthy eating habits were major barriers loss. Our data highlights discordance between understanding disease actual behaviour approaches manage it HCPs. The study addresses need align these gaps deliver optimal care PwO.

Language: Английский

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Obesity Management in South Asian Context

Apollo Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: April 11, 2025

Obesity is a chronic relapsing disease with rising prevalence in South Asia because of the changing economic and social landscape transition lifestyle. The issues obesity management are unique to Asians characteristic ‘thin-fat’ phenotype, diet high carbohydrate low protein contents, availability, affordability approval status various anti-obesity drugs cultural aspects this population. In article, we have reviewed literature sourced from India pertaining addressed steps for comprehensive streamlined approach part world.

Language: Английский

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Global burden of osteoarthritis in adults aged 30 to 44 years, 1990 to 2019: results from the Global Burden of Disease Study 2019

BMC Musculoskeletal Disorders, Journal Year: 2024, Volume and Issue: 25(1)

Published: April 19, 2024

Osteoarthritis (OA) is a common orthopedic disorder, and its incidence has been increasing among young adults in recent years. The purpose of this study to investigate the global, regional, national trends OA burden variation individuals aged 30 44 from 1990 2019.

Language: Английский

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Childhood Obesity and Its Comorbidities in High-Risk Minority Populations: Prevalence, Prevention and Lifestyle Intervention Guidelines

Nutrients, Journal Year: 2024, Volume and Issue: 16(11), P. 1730 - 1730

Published: May 31, 2024

The prevalence of childhood obesity and its associated comorbidities is a growing global health problem that disproportionately affects populations in low- middle-income countries (LMICs) minority ethnicities high-income (HICs). increased disparities among reflect two concerns: one HICs’ ineffective intervention approaches terms lifestyle, nutrition physical activity populations, the second virtually non-existent lifestyle interventions LMICs. This article provides guidelines on high-risk based understanding effectiveness preventative interventions. First, we highlight how inadequate screening by body mass index (BMI) can be resolved using objective adiposity fat percentage measurements alongside anthropometric physiological components, including lean tissue bone density. National healthcare prevention initiatives should embed cut-off points for ethnicities, especially Asian South within UK USA whose obesity-related metabolic risks are often underestimated. Secondly, underutilised children adolescents with comorbidities, ethnicity population groups. overwhelming evidence involving from ethnic shows personalised successful reversing secondary cardiometabolic disease risks, those related to cardiorespiratory capacity, blood pressure glucose/insulin levels. Interventions combining cultural contextualisation better engagement families most effective paediatric but non-uniform amongst different communities. A sustained impact achieved through involvement community, stakeholders comprising professionals, nutritionists, exercise science specialists policy makers. Our assessment primary fundamental reducing local improving quality life.

Language: Английский

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Obesity in the Asia-Pacific Region: Current Perspectives

Journal of Asian Pacific Society of Cardiology, Journal Year: 2024, Volume and Issue: 3

Published: June 5, 2024

Obesity has become a pandemic in the Asia-Pacific region, with an alarming rate of increase prevalence obesity. The impact obesity and its associated comorbidities goes beyond healthcare system, posing substantial burden not only on individual, but also society economy. In this review, we focus latest situation review diagnostic criteria obesity, management strategies access to treatment region. National guidelines are available some countries, reflecting recognition problem by professionals government bodies. Although range anti-obesity pharmacotherapies bariatric surgeries available, remains restricted reimbursement vary different parts Asia-Pacific. Prevention is key, as alone cannot reverse tide sustained partnership between patient clinician necessary manage chronic disease

Language: Английский

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