Assessment of gingival crevicular fluid levels of IL33 and sST2 in periodontitis patients with stage I-III disease DOI Open Access

Samar A. Abood,

Ayser Najah Mohammed

Immunopathologia Persa, Journal Year: 2024, Volume and Issue: 10(2), P. e40642 - e40642

Published: May 27, 2024

Introduction: Patients with chronic periodontitis exhibit significant interleukin-33 (IL-33) expression in their periodontal tissue. However, it is debatable, whether patients gingival crevicular fluids (GCFs) have increased levels of IL-33. The ligand the ST2 (suppression tumorigenity) receptor Toll-like receptor/IL-1R superfamily includes receptor, which exists two distinct versions; soluble (sST2), secreted, and ST2L, as a transmembrane form. In addition to measuring clinical parameters correlating them IL33 sST2 patients, goal this study was evaluate these biomarkers GCF (stage I, II, III) relative healthy controls. Objectives: present aimed individuals (stages compared those controls, assess compare periodontitis. Materials Methods: A total 162 participants participated study. Clinical measurements were made for probing pocket depth (PPD), plaque index (PI), attachment level (CAL), bleeding on (BOP). collected from each patient. To measure levels, enzyme-linked immunosorbent assays (ELISAs) used. Results: When comparing group control group, greater (P>0.001). Only stage II there association between PPD sST2, whereas no correlation detected markers. Conclusion: Compared exhibited sST2. This finding implies that pathogenesis health are both influenced by

Language: Английский

Expression of IL-33 in subjects with periodontitis: a systematic review and meta-analysis DOI Creative Commons
Mario Alberto Alarcón‐Sánchez, Norma Samanta Romero-Castro, Salvador Reyes-Fernández

et al.

European journal of medical research, Journal Year: 2024, Volume and Issue: 29(1)

Published: Aug. 29, 2024

Activation of the IL-33/ST2 axis leads to production proinflammatory cytokines and thus triggering osteoclastogenesis, which is why it plays an important role in immunopathogenesis periodontitis. The aim this study was compare IL-33 levels serum, plasma, saliva gingival crevicular fluid (GCF) subjects with chronic periodontitis (CP) comparison control group (CG).

Language: Английский

Citations

2
Assessment of gingival crevicular fluid levels of IL33 and sST2 in periodontitis patients with stage I-III disease DOI Open Access

Samar A. Abood,

Ayser Najah Mohammed

Immunopathologia Persa, Journal Year: 2024, Volume and Issue: 10(2), P. e40642 - e40642

Published: May 27, 2024

Introduction: Patients with chronic periodontitis exhibit significant interleukin-33 (IL-33) expression in their periodontal tissue. However, it is debatable, whether patients gingival crevicular fluids (GCFs) have increased levels of IL-33. The ligand the ST2 (suppression tumorigenity) receptor Toll-like receptor/IL-1R superfamily includes receptor, which exists two distinct versions; soluble (sST2), secreted, and ST2L, as a transmembrane form. In addition to measuring clinical parameters correlating them IL33 sST2 patients, goal this study was evaluate these biomarkers GCF (stage I, II, III) relative healthy controls. Objectives: present aimed individuals (stages compared those controls, assess compare periodontitis. Materials Methods: A total 162 participants participated study. Clinical measurements were made for probing pocket depth (PPD), plaque index (PI), attachment level (CAL), bleeding on (BOP). collected from each patient. To measure levels, enzyme-linked immunosorbent assays (ELISAs) used. Results: When comparing group control group, greater (P>0.001). Only stage II there association between PPD sST2, whereas no correlation detected markers. Conclusion: Compared exhibited sST2. This finding implies that pathogenesis health are both influenced by

Language: Английский

Citations

0