Surgical extraction with photobiomodulation as an adjunctive modality in patients at-risk for medication-related osteonecrosis of the jaw: retrospective study DOI Creative Commons
Gianluca Tenore, Ahmed Mohsen, Alessandro Del Vecchio

et al.

BMC Oral Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: April 24, 2025

The study aims to retrospectively assess and share the experience of use photobiomodulation (PBM) as an adjunctive surgical extraction in patients at-risk for medication-related osteonecrosis jaw (MRONJ) due a treatment history with bone-modifying agents. department database medical records were examined period between 2016 2023. inclusion criteria were; MRONJ current or previous agents, without antiangiogenic agents administration, who underwent single multiple dental extractions, subjected PBM preventive protocol, diagnosis development. protocol consisted four sessions, two sessions before intervention after intervention. parameters (per session) total power 0.6 W, time 15 min, frequency 30 kHz, energy 577.4 J. A 62 (58 females 4 males) fulfilled mean age 67.5 years. Complete healing development was shown 50 (80.65%) patients, 12 (19.35%) patients. statistical analysis revealed higher risk administration zoledronic acid (p = 0.029) undergoing corticosteroid therapy 0.039). While lower observed thyroid pathology 0.055). majority included showed complete modality. Corticosteroid systemic factor drug-related show significant associations MRONJ.

Language: Английский

Diagnosis of Oral Cancer With Deep Learning. A Comparative Test Accuracy Systematic Review DOI Creative Commons
Michele Nieri, Lapo Serni, Tommaso Clauser

et al.

Oral Diseases, Journal Year: 2025, Volume and Issue: unknown

Published: March 31, 2025

ABSTRACT Objective To directly compare the diagnostic accuracy of deep learning models with human experts and other methods used for clinical detection oral cancer. Methods Comparative studies involving patients photographic images mucosal lesions (cancer or non‐cancer) were included. Only using eligible. Medline, EMBASE, Scopus, Google Scholar, ClinicalTrials.gov searched until September 2024. QUADAS‐C assessed risk bias. A Bayesian meta‐analysis compared test accuracy. Results Eight included, none which had a low Three versus experts. The difference in sensitivity favored by 0.024 (95% CI: −0.093, 0.206), while specificity −0.041 −0.218, 0.038). Two postgraduate medical students. differences 0.108 −0.038, 0.324) 0.010 −0.119, 0.111), respectively. Both comparisons provided low‐level evidence. Conclusions Deep showed comparable to These outperformed students terms sensitivity. Prospective trials are needed evaluate real‐world performance models.

Language: Английский

Citations

0

Surgical extraction with photobiomodulation as an adjunctive modality in patients at-risk for medication-related osteonecrosis of the jaw: retrospective study DOI Creative Commons
Gianluca Tenore, Ahmed Mohsen, Alessandro Del Vecchio

et al.

BMC Oral Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: April 24, 2025

The study aims to retrospectively assess and share the experience of use photobiomodulation (PBM) as an adjunctive surgical extraction in patients at-risk for medication-related osteonecrosis jaw (MRONJ) due a treatment history with bone-modifying agents. department database medical records were examined period between 2016 2023. inclusion criteria were; MRONJ current or previous agents, without antiangiogenic agents administration, who underwent single multiple dental extractions, subjected PBM preventive protocol, diagnosis development. protocol consisted four sessions, two sessions before intervention after intervention. parameters (per session) total power 0.6 W, time 15 min, frequency 30 kHz, energy 577.4 J. A 62 (58 females 4 males) fulfilled mean age 67.5 years. Complete healing development was shown 50 (80.65%) patients, 12 (19.35%) patients. statistical analysis revealed higher risk administration zoledronic acid (p = 0.029) undergoing corticosteroid therapy 0.039). While lower observed thyroid pathology 0.055). majority included showed complete modality. Corticosteroid systemic factor drug-related show significant associations MRONJ.

Language: Английский

Citations

0