Pediatric allergy and immunology in North America—An introduction

Pediatric Allergy and Immunology, Journal Year: 2025, Volume and Issue: 36(1)

Published: Jan. 1, 2025

Language: Английский

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Comment on Lawson et al.

Pediatric Allergy and Immunology, Journal Year: 2024, Volume and Issue: 35(8)

Published: Aug. 1, 2024

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Editorial comments on “Risk and protective factors of asthma and mental health condition multimorbidity in a national sample of Canadian children”

Pediatric Allergy and Immunology, Journal Year: 2024, Volume and Issue: 35(11)

Published: Nov. 1, 2024

Joshua Lawson The coexistence of asthma and mental health problems in children poses a significant challenge for both clinicians families as these comorbidities can complicate treatment strategies negatively affect quality life. Poor control is known to have adverse effects on health.1 Conversely, children's mood anxiety disorders were among the most important variables predicting risk.2 In light recent studies, inadequate epithelial barrier integrity has been implicated pathogenesis several conditions with underlying immunologic mechanisms, extending disorders.3 Therefore, investigating prevalence etiology multimorbidity between condition, well factors contributing their coexistence, an interesting critical topic. this issue, "Risk protective condition national sample Canadian children" by et al. provides data (AMHM) determinants AMHM large cohort 47,871 patients. current cohort, 1.6% had AMHM. Despite low prevalence, study was almost twice high compared those without (21.1% vs. 11.6%).4 identifies risk that increase likelihood developing children, including allergic conditions, chronic physical exposure smoke. contrast, common all categories—asthma, AMHM—include female gender being born outside Canada. Other patterns associations found different categories, such adherence sleep rules, non-white ethnic background, living rural area, having frequent family meals.4 These lifestyle, environmental, demographic characteristics may be beneficial preventing children. Moreover there are additional associated studied, example educational level relationship members' alcohol, cigarette, cannabis habits make contributions our understanding multimorbidity. Clinically, findings reinforce importance early identification at risk, especially who lived urban settings entire lives, socioeconomic status, food insecurity, obesity, or exposed secondhand smoke through members. medicine, other fields, finding ways "to kill two birds one stone" often advantageous. focusing influence offer more comprehensive solutions. One notable from role diseases Previous also likely problems.1 This line previous research showing inflammation play development disorders, possibly inflammatory pathways psychosocial stress management conditions.5 Second environmental tobacco another particularly concerning factor identified. While respiratory health, exacerbating symptoms, well-established, it appears issues. association explained mechanisms increased oxidative disruption normal neurological development, further underscoring broad impact health.6 Interestingly, did not observe anticipated effect which reported some research, but authors focus Canada against captures essence how diverse microbial interactions crucial supporting immunological psychological resilience.7 conclusion, suggests interact various reduced preventable hygiene, healthy obesity control, reduction exposure. study, included adolescents aged 3 18 years, suggest older higher only younger Given significance age disease onset comorbidity, social behaviors future would benefit design longitudinal studies. Such studies provide clearer outcomes emerge over time individuals age. Although clear cause-and-effect difficult establish due cross-sectional perspective terms understanding, recognition, prevention seen asthmatic Ozge Can Bostan: Conceptualization; writing – original draft. Kalliopi Karipidi: Writing review editing. Ömer Kalayci: Philippe Eigenmann: None. peer history article available https://www.webofscience.com/api/gateway/wos/peer-review/10.1111/pai.14270.

Language: Английский

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Reply to Ching‐Heng Tsai and Lien‐Chung Wei

Pediatric Allergy and Immunology, Journal Year: 2024, Volume and Issue: 35(9)

Published: Sept. 1, 2024

Language: Английский

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