Haemodynamic Patterns in Reflex Syncope: Insights from Head-Up Tilt Tests in Adults and Children

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(6), P. 1874 - 1874

Published: March 11, 2025

Introduction: Vasovagal syncope is a prevalent condition marked by transient loss of consciousness due to abrupt decreases in systemic blood pressure and/or heart rate. Despite its clinical impact, the underlying haemodynamic mechanisms remain poorly defined, and data on age-related differences are limited sometimes contradictory. Objectives: This study aimed characterise adaptation patterns during head-up tilt (HUT) test adult (≥18 years) paediatric (<18 patients with recurrent reflex syncope, compared healthy controls. We sought identify distinct temporal signatures clarify potential mechanisms. Methods: In this prospective observational study, participants underwent continuous beat-to-beat monitoring cardiac output (CO), stroke volume (SV), rate (HR), total peripheral resistance (TPR) HUT. Linear mixed-effects models were used examine time-by-group interactions, post-hoc analyses adjusted for multiple comparisons. Effect sizes confidence intervals (CIs) reported quantify magnitude differences. Results: A 187 fainters (paediatric n = 81, 106) 108 non-fainters (including 30 controls) studied. Compared fainters, showed 24% larger decline CO from baseline (mean difference 1.1 L/min [95% CI: 0.5–1.7], p 0.003) 15–20 bpm higher peak HR (p 0.001) presyncope. Both subgroups experienced significant drops TPR, which more pronounced (effect size 0.27, 95% 0.12–0.42). Non-fainters maintained relatively stable haemodynamics, no decrease or TPR > 0.05). Age-related comparisons indicated heavier reliance modulation leading an earlier transition compensated pre-syncopal states. Conclusions: These findings demonstrate that exhibit than adults, alongside responses orthostatic stress. Targeted interventions address heightened chronotropic dependency—such as tilt-training protocols strategies improve venous return—may be particularly beneficial younger patients. An age-specific approach diagnosis management could risk stratification, minimise episodes, enhance patient outcomes.

Language: Английский

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The effects of Rajyoga mindfulness meditation training on heart rate variability in panic disorder: A randomized controlled trial

Indian Journal of Psychiatry, Journal Year: 2025, Volume and Issue: 67(3), P. 310 - 315

Published: March 1, 2025

Background: Panic disorder is associated with autonomic nervous system dysfunction and reduced heart rate variability (HRV). Enhancing HRV may help mitigate symptoms of panic disorder. This study investigated the effects Rajyoga mindfulness meditation training on in patients Methods: prospective randomized controlled trial included 110 recruited from a psychiatry department India. Participants were to either an 8-week intervention (n = 55) or waitlist control group receiving standard treatment alone. was measured at baseline after 8 weeks using time domain (SDRR, RMSSD, pNN50) frequency (total power, HF, LF, LF/HF ratio) parameters. Results: At baseline, there no significant differences demographics parameters between groups. After weeks, showed increases SDRR, pNN50, total power compared controls ( P < 0.05), indicating improved parasympathetic activity. The ratio decreased versus controls, suggesting shift toward predominance. Conclusions: Eight activity be beneficial adjunctive for enhancing regulation

Language: Английский

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The relationship between resting heart rate variability and sportive performance, sleep and body awareness in soccer players

BMC Sports Science Medicine and Rehabilitation, Journal Year: 2025, Volume and Issue: 17(1)

Published: March 24, 2025

Heart rate variability (HRV) is a key marker of autonomic nervous system function and has been proposed as tool for monitoring training adaptations. However, its relationship with performance beyond aerobic capacity remains unclear in football players. This study aimed to examine the associations between resting HRV capacity, agility, neuromuscular coordination, sleep quality, body awareness. Twenty-five male players (mean age 20 ± 3 years) underwent assessment via Polar H10 system. Performance tests included m Shuttle Test (VO2max), Illinois Agility Test, Hexagon (neuromuscular coordination), Vertical Jump Tests (muscular strength). Sleep quality awareness were assessed using Pittsburgh Quality Index Body Awareness Questionnaire. Score was positively correlated VO2max (r = 0.4, p 0.04), while LF/HF ratio showed negative correlation shuttle test distance (rs=-0.52, 0.007). Mean RR coordination 0.56, 0.004), 0.45, 0.024), (rs 0.46, 0.019). No significant correlations found muscular strength. Resting associated indicators players, supporting potential use physiological readiness Future research should establish reference values evaluate HRV-based interventions enhancement.

Language: Английский

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Simulated Virtual Reality Experiences for Predicting Early Treatment Response in Panic Disorder

Published: Jan. 1, 2025

Language: Английский

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Occupational stress as a risk factor for cardiovascular accidents in medical staff of anesthesiology and intensive care units (review)

Messenger of Anesthesiology and Resuscitation, Journal Year: 2025, Volume and Issue: 22(2), P. 139 - 148

Published: April 16, 2025

Introduction. Occupational stress is one of the most common causes cardiovascular catastrophe among emergency response personnel. The objective was to analyze literature sources on assessing level and its impact health indicators in medical staff anesthesiology intensive care units. Materials methods . analysis included 70 publications from PubMed e-library abstract databases for period 2017 2023. search carried out using keywords: professional burnout syndrome, stress, personality, anesthesiologist-resuscitator, unit, heart rate variability, provider anesthesiologist, physician, rhythm variability. After a primary examination abstracts, 20 articles were excluded review as there lack access full text or they devoted organizational prevention activities Results. It has been demonstrated that long working day more than 10 years associated with an increase likelihood developing coronary disease (CHD), especially men. A linear risk recurrent CHD attacks established time 40 hours week four after myocardial infarction. revealed severe occupational decrease HRV due parasympathetic influences. In resident anesthesiologists, maximum inhibition variability noted at stage induction anesthesia eve night watch. Conclusion. long-term sympathetic activity autonomic nervous system suppression impulses indicate high probability diseases stress.

Language: Английский

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Understanding the Psycho-Physiological Impact of Bullying on Adolescents: A Focus on Movement-Based Educational Interventions

Education Sciences, Journal Year: 2025, Volume and Issue: 15(5), P. 521 - 521

Published: April 23, 2025

Bullying and cyberbullying are significant challenges faced by children adolescents in their daily lives, often leading to severe psychological physiological harm. A promising avenue of research this area focuses on the stress responses triggered bullying experiences. This study aimed examine potential group task-oriented physical education as a mediator between stress-related responses, particularly relation heart rate variability. secondary objective was design assess program for management, named BOND (Building Opportunities through Networked Dynamics), tailored settings. The employed two-arm randomized parallel-group design, involving 160 students (average age = 14.67 years, SD ±0.61) from two schools southern Italy. participants were split into groups: one attended (held twice week 60 min), while other took part regular classes, (conducted min). Measurements taken both before after intervention. Students underwent assessments that included Coping Questionnaire Children Adolescents, Perceived Stress Scale, measurements vagus-mediated findings underscore positive impact psycho-physiological well-being affected bullying, highlighting simple yet effective intervention safeguarding student mitigating adverse effects bullying. However, future is necessary provide more comprehensive understanding phenomenon.

Language: Английский

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Heart Rate Variability Applications in Medical Specialties: A Narrative Review

Applied Psychophysiology and Biofeedback, Journal Year: 2025, Volume and Issue: unknown

Published: April 28, 2025

Language: Английский

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Emotion contagion and physiological synchrony: The more intimate relationships, the more contagion of positive emotions

Physiology & Behavior, Journal Year: 2023, Volume and Issue: 275, P. 114434 - 114434

Published: Dec. 11, 2023

Language: Английский

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Enhanced Brain-Heart Connectivity as a Precursor of Reduced State Anxiety After Therapeutic Virtual Reality Immersion

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 30, 2024

Abstract State anxiety involves transient feelings of tension and nervousness in response to threats, which can escalate into disorders if persistent. Despite treatments, 30%-50% individuals show limited improvement, neurophysiological mechanisms treatment responsiveness remain unclear, requiring the development objective biomarkers. In this study, we monitored multimodal electrophysiological parameters: heart rate variability (high-frequency, low-frequency, LF/HF ratio), EEG beta alpha relative power, brain-to-heart connectivity participants with real-life state anxiety. Participants underwent a therapeutic intervention combining virtual-reality immersion, hypnotic script, breath control exercise. Real-life was captured using STAI-Y1 scale before after intervention. We observed reduced immediately 16 out 27 participants. While all participants, independently their score, showed increased HRV low frequency only treatment-responders displayed overall autonomic tone (high HRV), midline power connectivity. Notably, ratio significant linear relationship reduction, higher ratios linked greater response. These findings suggest that cognitive regulation could serve as biomarker for efficacy, elevated facilitating improved cardiac responders. Significance Statement Elevated debilitating disorders, such generalized disorder, yet efficacy remains inconsistent, reliable biomarkers predicting outcomes are lacking. This study identifies key neural physiological markers effective reduction following virtual reality-based non-pharmacological healthy Anxiety is associated heightened (LF/HF enhanced highlight role modulation nervous system functioning By highlighting these biomarkers, research aims at advancing our understanding offering insights biomarker-driven, scalable interventions.

Language: Английский

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Basal ganglia theta power indexes trait anxiety in people with Parkinson's disease

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: June 5, 2024

Neuropsychiatric symptoms are common and disabling in Parkinson's disease (PD), with troublesome anxiety occurring one-third of patients. Management PD is challenging, hampered by insufficient insight into underlying mechanisms, lack objective measurements, largely ineffective treatments.In this study, we assessed the intracranial neurophysiological correlates patients treated deep brain stimulation (DBS) laboratory at home. We hypothesized that low-frequency (theta-alpha) activity would be associated anxiety.

Language: Английский

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