Rate of body weight gain during early gestation in F0 beef heifers has effects that extend multigenerationally to the F2 fetuses DOI

Friederike Baumgaertner,

Germán Darío Ramírez-Zamudio, Ana Clara B Menezes

et al.

Journal of Animal Science, Journal Year: 2024, Volume and Issue: 102

Published: Jan. 1, 2024

Our aim was to investigate the effects of maternal (F0) body weight (BW) gain during first 84 d gestation on composition, ovarian reserve, and hormonal metabolic parameters breeding-age F1 heifers, as well BW morphometry F2 fetuses. The study also evaluated effect mRNA relative abundance small intestine both heifers Crossbred Angus (F0; n = 100) were managed 0.20 kg/d (low [LG], 50) or 0.75 (moderate [MG], for gestation. Subsequently, F0 dams a common forage-based diet rest until weaning offspring. At 15 mo age, subset randomly selected current experiment (n 8 LG MG). Heifers bred via artificial insemination (AI; day 0), then harvested On days -10, 42, 84, recorded, blood collected analyzed concentrations glucose, non-esterified fatty acids, progesterone, insulin, insulin-like growth factor-1. carcasses, organs, gravid uteri, fetuses organs recorded at harvest. Visible follicles counted ovaries harvest, histology used count microscopic follicles. Liver jejunal samples from measure tissue oxygen consumption analysis. MG tended be 12 kg greater (P 0.06) than dams. Concentrations glucose 0.03) in group, with no differences other metabolites follicular populations ≥ 0.16). Interestingly, mammary glands heavier 0.05), placentas depth greater, respectively ≤ 0.10), heifers. Oxygen liver jejunum, jejunum not affected by rate However, NDUFC1, SDHA, UQCR1, PPARG genes upregulated 0.05) group. In conclusion, early exerts subtle pre-breeding offspring, impacts present placenta, gland, intestine.

Language: Английский

Rate of body weight gain during early gestation in F0 beef heifers has effects that extend multigenerationally to the F2 fetuses DOI

Friederike Baumgaertner,

Germán Darío Ramírez-Zamudio, Ana Clara B Menezes

et al.

Journal of Animal Science, Journal Year: 2024, Volume and Issue: 102

Published: Jan. 1, 2024

Our aim was to investigate the effects of maternal (F0) body weight (BW) gain during first 84 d gestation on composition, ovarian reserve, and hormonal metabolic parameters breeding-age F1 heifers, as well BW morphometry F2 fetuses. The study also evaluated effect mRNA relative abundance small intestine both heifers Crossbred Angus (F0; n = 100) were managed 0.20 kg/d (low [LG], 50) or 0.75 (moderate [MG], for gestation. Subsequently, F0 dams a common forage-based diet rest until weaning offspring. At 15 mo age, subset randomly selected current experiment (n 8 LG MG). Heifers bred via artificial insemination (AI; day 0), then harvested On days -10, 42, 84, recorded, blood collected analyzed concentrations glucose, non-esterified fatty acids, progesterone, insulin, insulin-like growth factor-1. carcasses, organs, gravid uteri, fetuses organs recorded at harvest. Visible follicles counted ovaries harvest, histology used count microscopic follicles. Liver jejunal samples from measure tissue oxygen consumption analysis. MG tended be 12 kg greater (P 0.06) than dams. Concentrations glucose 0.03) in group, with no differences other metabolites follicular populations ≥ 0.16). Interestingly, mammary glands heavier 0.05), placentas depth greater, respectively ≤ 0.10), heifers. Oxygen liver jejunum, jejunum not affected by rate However, NDUFC1, SDHA, UQCR1, PPARG genes upregulated 0.05) group. In conclusion, early exerts subtle pre-breeding offspring, impacts present placenta, gland, intestine.

Language: Английский

Citations

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