Effects of Marine-Derived Components on Cardiovascular Disease Risk Factors and Gut Microbiota Diversity DOI Creative Commons
Ingrid Lamminpää, Amedeo Amedei, Cinzia Parolini

et al.

Marine Drugs, Journal Year: 2024, Volume and Issue: 22(11), P. 523 - 523

Published: Nov. 20, 2024

Cardiovascular diseases (CVDs), which comprise coronary heart disease, hypertension, and stroke, collectively represent the number one cause of death globally. Atherosclerosis is dominant CVDs, its risk factors are elevated levels low-density lipoprotein cholesterol triglycerides, cigarette smoking, obesity, diabetes mellitus. In addition, diverse evidence highlights role played by inflammation clonal haematopoiesis, eventually leading to immunity involvement. The human microbiota project subsequent studies using next-generation sequencing technology have indicated that thousands different microbial species present in gut. Disturbances gut (GM) composition, i.e., dysbiosis, been associated with ranging from localised gastrointestinal disorders metabolic cardiovascular illnesses. Of note, experimental suggested GM, host immune cells, marine-derived ingredients work together ensure intestinal wall integrity. This review discusses current concerning links among ingredients, inflammatory disease. detail, we summarise impact fish-derived proteins/peptides algae components on CVD microbiome. Furthermore, describe interplay these dietary components, probiotics/prebiotics, CVDs.

Language: Английский

Immuno-oncological Challenges and Chemoresistance in Veterinary Medicine: Probiotics as a New Strategic Tool DOI
Muhammad Nisar, Tingdong Yan, Yi Cai

et al.

Probiotics and Antimicrobial Proteins, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 15, 2025

Language: Английский

Citations

0
Updating the Discontinuity Theory to the Extended Immunity: The Symmunobiome Concept DOI Creative Commons
Federico Boem, Ingrid Lamminpää, Amedeo Amedei

et al.

European Journal of Immunology, Journal Year: 2025, Volume and Issue: 55(4)

Published: April 1, 2025

ABSTRACT The immune system (IS) is commonly understood as a composed of specific cells and tissues that have evolved to contrast pathogens defend the host. By virtue this capacity, it has come be considered capable making an essential distinction, between self versus non‐self, which would contribute clear identity organism. However, in wake evolution ecology, growing evidence suggests so‐called system, also from symbiotic interactions with external agents, not just defensive merely protects organism but, on contrary, involved many global regulatory homeostatic functions. Moreover, performing these functions, IS only ensemble host but functionally constitutively determined by interaction set associated microorganisms, is, human microbiome. In scenario, open‐and‐shut microbiome itself functional part extended system. Organisms microbiomes together, therefore, form whole, constitutes privileged biological organization. light showing inadequacy traditional accounts, we propose extend supplement current conceptualization introducing notion symmunobiome. With term, intend characterize microbiome's own unavoidable component overall functionality. Therefore, suggest new determination, articulated three linked pillars—adaptive immunity, innate symmunobiome—to better grasp diverse functionality immunity.

Language: Английский

Citations

0
Effects of Marine-Derived Components on Cardiovascular Disease Risk Factors and Gut Microbiota Diversity DOI Creative Commons
Ingrid Lamminpää, Amedeo Amedei, Cinzia Parolini

et al.

Marine Drugs, Journal Year: 2024, Volume and Issue: 22(11), P. 523 - 523

Published: Nov. 20, 2024

Cardiovascular diseases (CVDs), which comprise coronary heart disease, hypertension, and stroke, collectively represent the number one cause of death globally. Atherosclerosis is dominant CVDs, its risk factors are elevated levels low-density lipoprotein cholesterol triglycerides, cigarette smoking, obesity, diabetes mellitus. In addition, diverse evidence highlights role played by inflammation clonal haematopoiesis, eventually leading to immunity involvement. The human microbiota project subsequent studies using next-generation sequencing technology have indicated that thousands different microbial species present in gut. Disturbances gut (GM) composition, i.e., dysbiosis, been associated with ranging from localised gastrointestinal disorders metabolic cardiovascular illnesses. Of note, experimental suggested GM, host immune cells, marine-derived ingredients work together ensure intestinal wall integrity. This review discusses current concerning links among ingredients, inflammatory disease. detail, we summarise impact fish-derived proteins/peptides algae components on CVD microbiome. Furthermore, describe interplay these dietary components, probiotics/prebiotics, CVDs.

Language: Английский

Citations

1