Child Organ Offer Process (cOOPS): Understanding Infectious Risk Assessment and Mitigation Strategies

Pediatric Transplantation, Journal Year: 2025, Volume and Issue: 29(4)

Published: May 7, 2025

ABSTRACT Introduction Pediatric Infectious Disease (PID) clinicians involved in solid organ transplantation often assess infection risk and mitigation strategies for donor offers. While some guidance is available, real‐life practice patterns have not been previously described. Methods We surveyed PID about acceptance associated posttransplantation interventions using 12 fictitious pediatric case scenarios through 3 PID‐specific listservs. Descriptive statistics were employed. Results 48 (71.6%) of 67 ID respondents offer assessment. Agreement was strong (> 80%) to accept (syphilis, severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2], MRSA, E. coli , TB [liver], rhino/enterovirus) or decline (undifferentiated encephalitis, [lung]) organs from these cases, while there less agreement cases with coccidioidomycosis, Chagas disease, multi‐drug‐resistant Acinetobacter baumannii influenza. Less present posttransplant monitoring antimicrobial administration. Practice varied testing treatment donors SARS‐CoV‐2 positive test, MRSA bacteremia, disease. Conclusions For many scenarios, high; however, improved education based on currently available recommendations may enhance decision‐making. The variability management highlights educational research opportunities optimize limit the impact donor‐derived infections recipients.

Language: Английский

Utilization of kidneys from tuberculosis-infected donors in renal transplantation: A case report

Transplant Immunology, Journal Year: 2024, Volume and Issue: 88, P. 102151 - 102151

Published: Nov. 20, 2024

Language: Английский