Impact of sex on the cerebrovascular response to incremental aerobic exercise in moderately trained endurance athletes DOI

Nassif Chamoun,

Audrey Drapeau,

Lawrence Labrecque

et al.

Journal of Applied Physiology, Journal Year: 2023, Volume and Issue: 134(6), P. 1470 - 1480

Published: April 27, 2023

The cerebrovascular response to incremental aerobic exercise is comparable between males and females. Whether this can be found in moderately trained athletes remains unknown. We aimed examine the effect of sex on until volitional exhaustion population. Twenty-two (11 M/11 F; age: 25 ± 5 vs. 26 6 yr, P = 0.6478; peak oxygen consumption: 55.8 5.2 48.3 4 mL/kg/min; 0.0011; training volume: 532 173 466 151 min/wk, 0.3554) performed a maximal ergocycle test. Systemic hemodynamics were measured. At rest, middle cerebral artery mean blood velocity (MCAvmean; 64.1 12.7 72.2 15.3 cm·s-1; 0.2713) was not different groups, whereas partial pressure end-tidal carbon dioxide ([Formula: see text], 42 3 37 2 mmHg, 0.0002) higher males. During MCAvmean ascending phase, changes (intensity: < 0.0001, sex: 0.3184, interaction: 0.9567) groups. Changes cardiac output text]) 0.0001) [Formula: text] descending 0.5522, 0.4828) 0.0550, 0.0003, 0.2715) (intensity 0.0280) These results suggest during females notwithstanding differences key flow determinants.NEW & NOTEWORTHY study endurance-trained spite arterial compared with exhaustion. This could help providing better understanding regulation exercise.

Language: Английский

Characterization of Demographic, Clinical, and Laboratory Risk Factors for Stroke in a Tertiary Hospital in Riyadh, Saudi Arabia DOI Open Access

A. Hussien,

Abdulaziz Khalid Alshehri,

Fayez Khalid Alanazi

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: April 14, 2024

Background Stroke is a major cause of death and long-term disability worldwide, with varying incidence risk factors across different populations. This study aims to analyze demographic, clinical, laboratory for stroke among the Saudi Arabian population enhance understanding its behavior associated mortality. Methods In this retrospective cohort study, we analyzed data from 3586 patients diagnosed hemorrhagic or non-hemorrhagic at King Fahad Medical City January 1, 2020, November 11, 2022. We collected on demographic variables, past medical history, social nationality, components. Statistical analyses were performed using IBM SPSS Statistics Windows, Version 27.0. (Armonk, NY: Corp.), significance set p<0.05. Results The was predominantly male (57.86%) within age group 51 80 years (58.8%). A significant portion nationals (99.6%), hypertension (50.2%) diabetes (40.4%) being most common comorbidities. Laboratory abnormalities related sodium potassium levels strongly linked mortality rates. Notably, ischemic type all groups, except under 16, where more prevalent. Conclusions Our findings reveal associations between population, highlighting impact hypertension, diabetes, electrolyte imbalances. underscores need targeted prevention management strategies in Arabia, aligning global trends mitigate burden disease.

Language: Английский

Citations

1
Progress on the Effects of Permissive Hypercapnia on the CNS During the Intraoperative Period: A Narrative Review DOI Open Access

Ya-zhi Xi,

Xiaoyu Jia,

Xue-lian Wei

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 29, 2024

Previous experimental findings and clinical evidence have shown the important role of carbon dioxide (CO

Language: Английский

Citations

1
Association between base excess and mortality in critically ill patients with ischemic stroke: a retrospective cohort study DOI Creative Commons
Jueheng Liu, Jiamei Li,

Xuting Jin

et al.

BMC Neurology, Journal Year: 2024, Volume and Issue: 24(1)

Published: Sept. 18, 2024

Language: Английский

Citations

1
Relationship between baseline bicarbonate and 30-day mortality in patients with non-traumatic subarachnoid hemorrhage DOI Creative Commons

Wenyuan Du,

Jingmian Yang,

Yanfang Lou

et al.

Frontiers in Neurology, Journal Year: 2024, Volume and Issue: 14

Published: Jan. 3, 2024

Objective This study aimed to explore the relationship between baseline bicarbonate levels and 30-day mortality in individuals with non-traumatic subarachnoid hemorrhage (SAH). Methods Patients SAH were chosen from Medical Information Mart for Intensive Care (MIMIC)-IV database. The was examined using Cox regression models. Restricted cubic splines used test hypothesis that there an association mortality. With use of Kaplan–Meier survival curve analysis, we looked deeper into validity these correlations. To find subgroups differences, interaction tests utilized. Results retrospective cohort consisted 521 participants total. Bicarbonate had a negative death at 30 days (HR = 0.93, 95%CI: 0.88–0.98, p 0.004). Next, divided quartile groups. In comparison reference group Q1 (20 mEq/L), groups Q3 (23–25 mEq/L) Q4 (26 adjusted HR values 0.47 (95%CI: 0.27–0.82, 0.007) 0.56 0.31–0.99, 0.047). No definite conclusions can be derived this study, since is no obvious link Patients’ increased statistically significantly ( &lt; 0.001, K–M analysis) patients low levels. remained consistent stratified observed interactions. Conclusion Finally, negatively associated are more risk if their low.

Language: Английский

Citations

1
Impact of sex on the cerebrovascular response to incremental aerobic exercise in moderately trained endurance athletes DOI

Nassif Chamoun,

Audrey Drapeau,

Lawrence Labrecque

et al.

Journal of Applied Physiology, Journal Year: 2023, Volume and Issue: 134(6), P. 1470 - 1480

Published: April 27, 2023

The cerebrovascular response to incremental aerobic exercise is comparable between males and females. Whether this can be found in moderately trained athletes remains unknown. We aimed examine the effect of sex on until volitional exhaustion population. Twenty-two (11 M/11 F; age: 25 ± 5 vs. 26 6 yr, P = 0.6478; peak oxygen consumption: 55.8 5.2 48.3 4 mL/kg/min; 0.0011; training volume: 532 173 466 151 min/wk, 0.3554) performed a maximal ergocycle test. Systemic hemodynamics were measured. At rest, middle cerebral artery mean blood velocity (MCAvmean; 64.1 12.7 72.2 15.3 cm·s-1; 0.2713) was not different groups, whereas partial pressure end-tidal carbon dioxide ([Formula: see text], 42 3 37 2 mmHg, 0.0002) higher males. During MCAvmean ascending phase, changes (intensity: < 0.0001, sex: 0.3184, interaction: 0.9567) groups. Changes cardiac output text]) 0.0001) [Formula: text] descending 0.5522, 0.4828) 0.0550, 0.0003, 0.2715) (intensity 0.0280) These results suggest during females notwithstanding differences key flow determinants.NEW & NOTEWORTHY study endurance-trained spite arterial compared with exhaustion. This could help providing better understanding regulation exercise.

Language: Английский

Citations

2