Analysis of influencing factors of exercise systolic blood pressure response in nonalcoholic fatty liver disease aged 40–60 years DOI
Xiaoyan Hao, Huihui Zhang,

Honghai He

et al.

Postgraduate Medicine, Journal Year: 2024, Volume and Issue: 137(1), P. 79 - 85

Published: Nov. 29, 2024

This study investigated the influencing factors of exercise systolic blood pressure response (ESBPR) by cardiopulmonary test (CPX) in nonalcoholic fatty liver disease (NAFLD) people aged 40-60 years. A total 603 adults were enrolled this study. The inclusion criteria cross-sectional who underwent health checks and CPX. There significant differences body mass Index (BMI) (26.80 ± 2.64 VS 23.31 2.41, p < 0.001) kg/m2, fasting glucose (FPG) (5.56 0.94 5.13 0.55, mmol/L, alanine aminotransferase (ALT), aspartate transaminase (AST), triglycerides (TG), high-density lipoprotein-cholesterol (HDL-C) (1.13 0.22 1.43 0.33, low-density (LDL-C) (3.21 0.79 2.99 0.68, = resting (SBP) (123.53 14.73 118.79 14.79, mmHg, diastolic (DBP) (80.29 9.62 75.27 10.41, peak SBP (184.01 23.50 172.81 24.95, DBP (87.47 10.50 84.01 11.46, oxygen pulse (VO2/HR) (0.88 0.15 0.92 0.16, 0.004) ml/beat, maximum heart rate, carbon dioxide Ventilation equivalent (VE/VCO2) (25.84 4.43 25.12 3.58, 0.038), uptake (VO2 peak) (1.78 0.45 1.56 0.46, mL/min between NAFLD control groups. VE/VCO2 (OR 0.822, 0.036) uptake/work rate (VO2/WR) 0.517, 0.021) mL/min/watt associated with a lower risk ESBPR subjects. Resting was higher patients 1.059, 0.003) overweight subjects 1.075, 0.002). 1.268, 0.045), skeletal-muscle 1.305, 0.001), SMI 1.315, linked to an elevated individuals. Our findings indicate that is increased individuals Furthermore, subjects, VO2/WR found be correlated decreased ESBPR, whereas ESBPR. will provide research basis for have at adverse events during exercise.

Language: Английский

Structural and functional impairments of skeletal muscle in patients with postacute sequelae of SARS-CoV-2 infection DOI
Marta Colosio, Lorenza Brocca,

Marco Gatti

et al.

Journal of Applied Physiology, Journal Year: 2023, Volume and Issue: 135(4), P. 902 - 917

Published: Sept. 7, 2023

Following acute coronavirus disease 2019 (COVID-19), a substantial proportion of patients showed symptoms and sequelae for several months, namely the postacute COVID-19 (PASC) syndrome. Major phenomena are exercise intolerance, muscle weakness, fatigue. We aimed to investigate physiopathology intolerance in with PASC syndrome by structural functional analyses skeletal muscle. At least 3 mo after infection, nonhospitalized (

Language: Английский

Citations

37

Muscle oxygen saturation rates coincide with lactate-based exercise thresholds DOI
Philip M. Batterson, Brett S. Kirby,

Georg Hasselmann

et al.

European Journal of Applied Physiology, Journal Year: 2023, Volume and Issue: 123(10), P. 2249 - 2258

Published: June 1, 2023

Language: Английский

Citations

17

Stretchable Multi‐Channel Ionotronic Electrodes for In Situ Dual‐Modal Monitoring of Muscle–Vascular Activity DOI Open Access
Hang Zhao, Shuai Wang, Tengfei Li

et al.

Advanced Functional Materials, Journal Year: 2023, Volume and Issue: 34(2)

Published: Sept. 26, 2023

Abstract In situ dual‐modal detection of electrophysiology (EP) and blood oxygen (BO) during muscle–vascular activity is crucial for healthcare human–machine interaction. It requires an integrated monitoring system: a transparent electrode EP directly adhered to skin near‐infrared spectroscopy (NIRs) layer BO detection. particular, the multi‐channel, highly transparent, stretchable electrodes should be well developed. this study, 16‐channel ionotronic are fabricated based on printable ionogel, demonstrating excellent properties such as high transparency, large stretchability, wet adhesion, biocompatibility, softness, long‐term stability. The exhibits stable contact impedance 24 h 2‐week periodic monitoring. outperforms gold by providing with minimal interference in NIRs An negative correlation found between intensity level over time. This study paves way designing ionotronics synchronous optical‐related highlights potential use system coupling neurocience rehabilitation.

Language: Английский

Citations

11

Monitoring skeletal muscle oxygen saturation kinetics during graded exercise testing in NCAA division I female rowers DOI Creative Commons
Drake A. Eserhaut,

Joseph M. DeLeo,

J. Provost

et al.

Frontiers in Physiology, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 17, 2025

Purpose The purpose of this study was to analyze changes in skeletal muscle oxygen saturation (SmO 2 ) kinetics during exercise female rowers both acutely and longitudinally relation blood lactate (BLa). We also aimed determine the agreement statistical equivalence between physiological thresholds derived from SmO BLa kinetics. Methods Twenty-three NCAA Division I were tested throughout 2023–2024 academic year. Of these, 11 athletes completed at least two near-infrared spectroscopy (NIRS)-equipped GXTs, with data analyzed for longitudinal changes. A 7x4-min discontinuous GXT protocol performed by all athletes. First second breakpoints BP1 BP2) estimated via piecewise linear regression modeling, (LT 1 LT calculated using ADAPT software. Paired-samples t-tests assessed differences, one-sided tests (TOST). Agreement determined Bland-Altman analysis yielding mean differences (MD) 95% limits (LoA). Intraclass correlation coefficients (ICC 2,1 calculated. Results No difference found BP2 (MD = −5.76W [95% LoA −38.52 22.25W], p 0.134), moderate-to-good levels 0.67 CI: 0.36–0.85], &lt; 0.001), no (p 0.117). This not case , NIRS significantly underestimating −8.14W −38.90 27.37W], 0.026), poor-to-moderate 0.24 −0.13–0.58], 0.10), 0.487). Additionally, recovery resat) 1-min rest intervals increased response graded increases intensity 0.001, η 0.71), higher intensities appearing blunt effect (step 6 – step 7: MD −0.16%⋅s -1 0.69). statistically significant observed LT’s or BP’s season. Conclusion In collegiate rowers, may be a tool that compliments testing when determining threshold (i.e., ). However, inter-individual variablility exists LT2 paired lack suggest are interchangeable. While standalone replacement, if used combination traditional methods complimentary helps inform individual athlete training zone prescription.

Language: Английский

Citations

0

Muscle oxidative capacity but not specific force is greater in aerobic versus resistance trained young adults DOI
Michael R. Perlet,

Genevieve B. Batman,

Kyndall V. Ransom

et al.

European Journal of Applied Physiology, Journal Year: 2025, Volume and Issue: unknown

Published: April 13, 2025

Language: Английский

Citations

0

Near infrared spectroscopy for the photodiagnosis of osteonecrosis, a future perspective. Mini historical review DOI

Rodrigo Antico Benetti,

Paula Ricci Arantes,

Pedro Oliveira

et al.

Journal of Near Infrared Spectroscopy, Journal Year: 2025, Volume and Issue: unknown

Published: April 3, 2025

Purpose: Osteonecrosis is a condition resulting from the death of bone tissue caused by loss vascularization, leading to exposure necrotic bone. Noninvasive optical techniques capable evaluating hemodynamic status as near infrared (NIR) spectroscopy have been studied for diagnosis osteonecrosis. This study aims highlight studies in which NIR was used evaluate characteristics, discussing its usefulness perfusion In this narrative review 16 PUBMED were selected, that provided initial evidence pattern normal identified different spectral found injured tissue. These suggest also has reproducibility and associations with other well-known imaging methodologies, indicating could become potential technique osteonecrosis real assessments superficial surfaces. It may be advantageous early asymptomatic cases lead compromised microcirculation. Due variability between data available, standard normality not yet established, making comparisons patients or establishment cutoff value hypoperfusion states difficult.

Language: Английский

Citations

0

Oxidative and O2 diffusive function in triceps brachii of recreational to world class swimmers DOI Creative Commons

Simone Villanova,

Elisa Pastorio, Andrea Pilotto

et al.

Experimental Physiology, Journal Year: 2025, Volume and Issue: unknown

Published: April 25, 2025

Abstract This study aimed to evaluate in vivo oxidative capacity and relative resistance O 2 diffusion using near‐infrared spectroscopy (NIRS) the m. triceps brachii of recreational world class swimmers their relationships with swimming performance. Twenty‐eight were enrolled assigned into three subgroups according level: ‘recreational/trained’ (Tier 1/2; n = 8), ‘national’ 3; 12) ‘international/world class’ 4/5; 8). Performance was evaluated by 100 m freestyle trials. Training volume measured self‐reported distance (km/week). The recovery k non‐invasively estimated NIRS through repeated intermittent occlusions under two conditions: well‐oxygenated ( HIGH ) low availability LOW ). difference between (Δ calculated as an index diffusion. FINA points performance differed among all groups. greater Tier 4/5 (34.0 ± 5.5 km week −1 3 (35.5 11.6 than 1/2 (6.4 1.8 (3.18 0.41 2.79 0.40 min versus (2.10 0.36 ; P < 0.002). correlated points, training volume. ∆ not different tiers associated or M. positively swimmers. , which reflects diffusion, athletes. These data suggest that is muscle diffusing exerts a similar diffusive flow across

Language: Английский

Citations

0

The Oxygen Cascade from Atmosphere to Mitochondria as a Tool to Understand the (Mal)adaptation to Hypoxia DOI Open Access
Michele Samaja, Sara Ottolenghi

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(4), P. 3670 - 3670

Published: Feb. 12, 2023

Hypoxia is a life-threatening challenge for about 1% of the world population, as well contributor to high morbidity and mortality scores in patients affected by various cardiopulmonary, hematological, circulatory diseases. However, adaptation hypoxia represents failure relevant portion cases pathways potential often conflict with well-being generate diseases that certain areas still afflict up one-third populations living at altitude. To help understand mechanisms maladaptation, this review examines steps oxygen cascade from atmosphere mitochondria distinguishing patterns related physiological (i.e., due altitude) pathological pre-existing disease) hypoxia. The aim assess ability humans adapt multidisciplinary approach correlates function genes, molecules, cells physiologic outcomes. We conclude that, most cases, it not itself generates diseases, but rather attempts condition. This underlies paradigm shift when becomes excessive, translates into maladaptation.

Language: Английский

Citations

9

Microvascular and oxidative stress responses to acute high-altitude exposure in prematurely born adults DOI Creative Commons
Giorgio Manferdelli, Benjamin J. Narang, Vincent Pialoux

et al.

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: April 26, 2023

Premature birth is associated with endothelial and mitochondrial dysfunction, chronic oxidative stress, which might impair the physiological responses to acute altitude exposure. We assessed peripheral stress high-altitude exposure in preterm adults compared term born controls. Post-occlusive skeletal muscle microvascular reactivity capacity from oxygen consumption recovery rate constant (k) were determined by Near-Infrared Spectroscopy vastus lateralis of seventeen adults. Measurements performed at sea-level within 1 h arrival (3375 m). Plasma markers pro/antioxidant balance both conditions. Upon exposure, sea-level, participants exhibited a lower reperfusion (7 ± 31% vs. 30 30%, p = 0.046) level, but higher k (6 32% -15 21%, 0.039), than their peers. The altitude-induced increases plasma advanced oxidation protein products catalase (35 61% -13 48% 67 64% 15 61%, 0.034 0.010, respectively) xanthine oxidase (29 82% 159 162%, 0.030) In conclusion, blunted responsiveness, larger may compromise acclimatization healthy preterm.

Language: Английский

Citations

9

Contraction intensity affects NIRS-derived skeletal muscle oxidative capacity but not its relationships to mitochondrial protein content or aerobic fitness DOI
Thomas R. Tripp,

Rachel M. McDougall,

Barnaby P. Frankish

et al.

Journal of Applied Physiology, Journal Year: 2023, Volume and Issue: 136(2), P. 298 - 312

Published: Dec. 7, 2023

To further refine the near-infrared spectroscopy (NIRS)-derived measure of skeletal muscle oxidative capacity in humans, we sought to determine whether exercise stimulus intensity affected τ value and/or influenced magnitude correlations with vitro measures mitochondrial content and vivo indices performance. Males (

Language: Английский

Citations

7