Future of Magnetic Sensors Applications in Early Prediction of Cardiac Health Status

Current Problems in Cardiology, Journal Year: 2025, Volume and Issue: unknown, P. 103022 - 103022

Published: Feb. 1, 2025

Language: Английский

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High-resolution computational modeling of Transcranial Photobiomodulation: Light propagation and thermal effects

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 19, 2025

Abstract Background Transcranial Photobiomodulation (tPBM) is the non-invasive application of light to modulate underlying brain activity. There increasing interest in evaluating tPBM as a therapeutic option. The typical technological questions are extent penetration and associated tissue temperature increases. Limited computational efforts quantify these aspects restricted simplified models. Methods We consider 3D high-resolution (1 mm) anatomically realistic head model simulate at 800 nm wavelength using power densities spanning three decades (10, 100, 1,000) mW/cm 2 . intended target was F3 region. also tested time-variant 100 for up 20 minutes. Finally, rises American National Standards Institute (ANSI) safety limit 330 investigated test case. Results Our predictions reveal that induced cortical irradiance largely focal demarcated by shape source. Around 1% injected reaches gray matter. Aligned with previous efforts, scalp accounts greatest loss (∼65%). reduces hundredth value from matter ∼113 mm perpendicular distance its surface. growing halo-like effect level CSF which extended down cortex. found be mainly responsible this effect. observe increases 0.38°C 3.76°C 1,000 density, respectively. corresponding predicted 0.06°C 0.57°C. As expected, absorption linear applied density. While maximum linearly less slowly Transient analysis density demonstrates expected rise stimulation duration. Temperature asymptote ∼ 10 Conclusions presents unique potential directly impose desired spatial profile simple alteration size Usage exceeds limits. Contrary prior reports, can exceed >10 cm

Language: Английский

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Photobiomodulation in biological tissues: Light penetration, dosimetry, and potential applications

Optics and Lasers in Engineering, Journal Year: 2025, Volume and Issue: 186, P. 108852 - 108852

Published: Jan. 27, 2025

Language: Английский

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Normal and Melanoma Skin Visualized, Quantified and Compared by in vivo Photoacoustic Imaging

Photoacoustics, Journal Year: 2025, Volume and Issue: 42, P. 100693 - 100693

Published: Jan. 29, 2025

Photoacoustic imaging (PAI) shows promise for skin cancer diagnosis by detecting chromophores like melanin, hemoglobin, lipids, and collagen. While most studies focus on malignant lesions, understanding normal variability across anatomical regions is crucial validating PAI's clinical application its use in melanoma diagnosis. We assessed 20 healthy volunteers from three different body locations using a PAI system compared suspicious looking pigmented including melanomas, to adjacent (n = 74). Higher deoxyhemoglobin levels were observed the ankle cheek volar forearm, while collagen showed minimal variation. Patients with lesions had significantly higher (p 0.001) than skin, difference not seen benign lesions. These findings suggest that may help diagnose malignancies identifying increased vascularity cancers, differences should be considered during diagnostic work-up.

Language: Английский

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Micropore visualization and lifetime following microneedle application to skin of differing pigments.

PubMed, Journal Year: 2025, Volume and Issue: unknown

Published: March 5, 2025

Language: Английский

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Dual-ratio approach to pulse oximetry and the effect of skin tone

Journal of Biomedical Optics, Journal Year: 2024, Volume and Issue: 29(S3)

Published: Oct. 12, 2024

SignificancePulsatile blood oxygen saturation (SpO2) via pulse oximetry is a valuable clinical metric for assessing delivery. Individual anatomical features, including skin tone, may affect current optical methods.AimWe developed an method based on dual-ratio (DR) measurements to suppress individual confounds SpO2.ApproachWe designed DR-based finger oximeter, hypothesizing that DR would from coupling and superficial tissue absorption. This tested using Monte Carlo simulations in vivo experiments.ResultsDifferent melanosome volume fractions the epidermis, surrogate cause changes recovered SpO2 order of 1% simulation vivo. Different heterogeneous pulsatile hemodynamics greater 10% simulations. with showed less variability than traditional single-distance (SD) transmission method.ConclusionsFor models methods considered here, are strongly impacted by hemodynamics. be larger tone bias, which known confound measurements. The partial suppression suggests promise oximetry.

Language: Английский

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Pulse oximetry in pediatric care: Balancing advantages and limitations

World Journal of Clinical Pediatrics, Journal Year: 2024, Volume and Issue: 13(3)

Published: Aug. 29, 2024

Pulse oximetry has become a cornerstone technology in healthcare, providing non-invasive monitoring of oxygen saturation levels and pulse rate. Despite its widespread use, the inherent limitations challenges that must be addressed to ensure accurate reliable patient care.

Language: Английский

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Imaging of the vascular distribution of the outer ear using optical coherence tomography angiography for highly accurate positioning of a hearable sensor

APL Bioengineering, Journal Year: 2024, Volume and Issue: 8(2)

Published: May 23, 2024

Novel hearable technology is securely and comfortably positioned within the ear canal minimizing inaccuracies caused by accessory movements during activities. Despite extensive research on technologies outer ear, there a lack of in field vascular imaging quantitative analysis

Language: Английский

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Evaluation of video-based rPPG in challenging environments: Artifact mitigation and network resilience

Computers in Biology and Medicine, Journal Year: 2024, Volume and Issue: 179, P. 108873 - 108873

Published: July 24, 2024

Video-based remote photoplethysmography (rPPG) has emerged as a promising technology for non-contact vital sign monitoring, especially under controlled conditions. However, the accurate measurement of signs in real-world scenarios faces several challenges, including artifacts induced by videocodecs, low-light noise, degradation, low dynamic range, occlusions, and hardware network constraints. In this article, systematic comprehensive investigation these issues is conducted, measuring their detrimental effects on quality rPPG measurements. Additionally, practical strategies are proposed mitigating challenges to improve dependability resilience video-based systems. Methods effective biosignal recovery presence limitations detailed, along with denoising inpainting techniques aimed at preserving video frame integrity. Compared previous studies, paper addresses broader range variables demonstrates improved accuracy across various methods, emphasizing generalizability applications diverse varying data quality. Extensive evaluations direct comparisons demonstrate effectiveness approaches enhancing measurements challenging environments, contributing development more reliable monitoring technologies.

Language: Английский

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Combination of gold nanoparticles with near-infrared light as an alternative approach for melanoma management

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 668, P. 124952 - 124952

Published: Nov. 14, 2024

Language: Английский

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