Thresholding Based Decision Based Algorithm for the Removal of Impulsive Artifacts in Images

Wireless Personal Communications, Journal Year: 2025, Volume and Issue: unknown

Published: March 5, 2025

Language: Английский

Spatial coherence analysis of an intense ultra-flat white laser

Acta Physica Sinica, Journal Year: 2025, Volume and Issue: 74(11), P. 0 - 0

Published: Jan. 1, 2025

White light is typically considered incoherent; however, the recently popular supercontinuum laser—also known as white laser—that spans visible spectrum, features high laser intensity and good coherence, challenging this traditional limitation. The has a wide range of applications, including multi-channel confocal microscopy, color holography, interferometric surface topography. Although lasers have been proposed developed extensively in terms technology, specific analyses their optical wave properties—especially spatial coherence—are still lacking. Since many applications impose certain requirements on coherence light, lack research into has, to some extent, limited practical use.<br>This paper presents detailed experimental study analysis wavefront intensity, polarization characteristics, high-intensity, ultra-flat spectrum independently by our group 2023. was generated broadening high-intensity Ti:sapphire femtosecond through second- third-order nonlinear effects.<br>A bandpass filter used extract eight components from laser, with central wavelengths ranging 405 nm 700 bandwidth 10 each. By measuring performance these quasi-monochromatic lasers, characteristics across can be evaluated.<br>CCD imaging collimated spots revealed that intensities exhibit quasi-Gaussian distribution uniform beam profiles. Polarization measurements using polarizers at various angles showed linearly polarized. A Young's Double-Slit Interferometer (YDSI) measure interference fringe contrast beams assess coherence. results average 0.77, little variation among different wavelengths. This indicates excellent range.<br>The all distributions, linear polarization, inherits properties laser. All data provides valuable guidance for application areas such tomography, microscopic imaging, other fields require degree

Language: Английский

Validation of label-free optical imaging markers of pancreatic cancer using spatial transcriptomics

Published: March 12, 2024

Label-free biomedical imaging represents a range of powerful technologies used to visualize natural sources biological contrast. techniques such as autofluorescence and fluorescence lifetime measure contrast produced by various cellular products provide high sensitivity for detecting tissue changes that occur with disease onset. However, major limitation these modalities, many label-free modalities broadly, is the lack robust validation methods confirm signal specificity. Moreover, existing approaches are limited assessing correlations fail mechanistic information into pathological events. Spatially resolved gene sequencing (e.g., spatial transcriptomics) tool gain detailed insight properties creating 2-D maps variations in expression influence properties. Thus, represent an avenue markers through examination how image features correspond expression. Toward this aim, we performed on specimens from four patients presenting pancreatic neuroendocrine tumors. We then transcriptome serial sections transcriptome-wide signatures. assessed biomarkers related metabolism, vasculature, extracellular matrix After registering images transcriptomic signatures, k-means clustering, correlation between differentially expressed genes associated interest. Specifically, aimed examine established optical redox ratio), along identifying other potential connections optics genetics. The results show transcriptomics can be effective markers, while simultaneously providing additional improve specificity studies.

Language: Английский