A comprehensive overview of diffuse correlation spectroscopy: theoretical framework, recent advances in hardware, analysis, and applications

NeuroImage, Journal Year: 2024, Volume and Issue: 298, P. 120793 - 120793

Published: Aug. 15, 2024

Diffuse correlation spectroscopy (DCS) is a powerful tool for assessing microvascular hemodynamic in deep tissues. Recent advances sensors, lasers, and learning have further boosted the development of new DCS methods. However, newcomers might feel overwhelmed, not only by already-complex theoretical framework but also broad range component options system architectures. To facilitate entry to this exciting field, we present comprehensive review hardware architectures (continuous-wave, frequency-domain, time-domain) summarize corresponding models. Further, discuss applications highly integrated silicon single-photon avalanche diode (SPAD) sensors DCS, compare SPADs with existing other components (lasers, correlators), as well data analysis tools, including learning. Potential medical diagnosis are discussed an outlook future directions provided, offer effective guidance embark on research.

Language: Английский

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A review on time domain diffuse optics: principles and applications on human biological tissues

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown

Published: April 9, 2025

Abstract The term diffusive media refers to all the for which photon diffusion equation provides an accurate description of light propagation. Indeed, this is case a plethora natural media, such as biological tissues and agricultural products, when illuminated by red near-infrared light. Diffuse Optics (DO) branch that studies how absorption scattering phenomena affect propagation in media. In review paper, we present introduction time domain (TD) DO, specific implementation DO employs picosecond pulses, fast sensitive photodetectors timing electronics record distribution time-of-flight (or path lengths) By interpreting TD signals with physical model provided theory, it possible estimate properties medium can be related physiological pathological conditions. We focus on principles building blocks instrumentation, applications targeting human (such brain, breast, muscle, others).

Language: Английский

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Time-resolved near-infrared spectroscopy in monitoring acute ischemic stroke patients – Case study

Journal of Applied Biomedicine, Journal Year: 2024, Volume and Issue: 44(1), P. 149 - 160

Published: Jan. 1, 2024

Language: Английский

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Effect of quantitative consciousness index on seizure parameters during electroconvulsive therapy in patients with major depressive disorder

World Journal of Psychiatry, Journal Year: 2024, Volume and Issue: 14(9), P. 1375 - 1385

Published: Sept. 10, 2024

Electroconvulsive therapy (ECT) is both an effective treatment for patients with major depressive disorder (MDD) and a noxious stimulus. Although some studies have explored the effect of sedation depth on seizure parameters in ECT, there little research stimulation response to ECT. In this study, we used two electroencephalography (EEG)-derived indices, quantitative consciousness (qCON) index nociceptive (qNOX) index, monitor sedation, hypnosis, MDD undergoing acute

Language: Английский

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How the heterogeneity of the severely injured brain affects hybrid diffuse optical signals: case examples and guidelines

Neurophotonics, Journal Year: 2024, Volume and Issue: 11(04)

Published: Oct. 18, 2024

A shortcoming of the routine clinical use diffuse optics (DO) in injured head has been that results from commercial near-infrared spectroscopy-based devices are not reproducible, often give physiologically invalid values, and differ among systems. Besides limitations due to physics continuous-wave light sources, one culprit is heterogeneity underlying morphological functional abnormalities probed tissue.

Language: Английский

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Quando o índice bispectral (BIS) pode fornecer valores espúrios: revisão

Journal Archives of Health, Journal Year: 2024, Volume and Issue: 5(3), P. e1739 - e1739

Published: July 10, 2024

Introdução: O índice bispectral (BIS) é um parâmetro derivado de ondas do eletroencefalograma (EEG) que permite avaliar o grau sedação paciente durante a anestesia geral, ajudando prevenir superdosagem medicamentos e evitar despertares intra-operatórios com memória, uma condição temida pela equipe anestesiologistas associada graves sequelas psicológicas. Este estudo tem como objetivo revisar literatura sobre as diversas possibilidades interferências nos valores BIS, demonstrando ele não deve ser avaliado forma isolada, visto seu valor pode sofrer alterações devido diversos fatores, condições clínicas (glicemia, temperatura, pressão arterial, postura compressiva, fatores neurológicos etilismo), equipamentos elétricos, interações anestésicos outros fármacos, próprio monitor. Apesar aprimoramento ao longo dos anos seus benefícios, modelo apresentar espúrios, falsamente elevados ou reduzidos, devem conhecidos pelos profissionais utilizam essa ferramenta para minimizar complicações inerentes.

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Falhas na anestesia subaracnoidea: revisão

Journal Archives of Health, Journal Year: 2024, Volume and Issue: 5(3), P. e1740 - e1740

Published: July 10, 2024

A técnica de bloqueio subaracnoideo é um dos procedimentos mais antigos da anestesiologia, observando-se relatos seu emprego na literatura científica há pelo menos 100 anos. consolidação desse método anestésico decorre sua aparente facilidade prática, aplicabilidade em variados cirúrgicos e alternativa viável ao uso bloqueadores neuromusculares, como os utilizados anestesias gerais. Não obstante, apesar elevada curva conhecimento ampla popularidade, são observadas falhas bloqueios subaracnoideos associadas a diversos fatores, tais variação delimitação anatômica, volume do infundido, pressão aplicada durante técnica, entre outros. Dessa forma, faz-se necessária sistematização procedimento, com o objetivo diminuir possíveis complicações por causas secundárias evitáveis.

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