Modality-Level Obstacles and Initiatives to Improve Representation in Fetal, Infant, and Toddler Neuroimaging Research Samples

Developmental Cognitive Neuroscience, Journal Year: 2025, Volume and Issue: 72, P. 101505 - 101505

Published: Jan. 5, 2025

Fetal, infant, and toddler (FIT) neuroimaging researchers study early brain development to gain insights into neurodevelopmental processes identify markers of neurobiological vulnerabilities target for intervention. However, the field has historically excluded people from global majority countries marginalized communities in FIT research. Inclusive representative samples are essential generalizing findings across modalities, such as magnetic resonance imaging, magnetoencephalography, electroencephalography, functional near-infrared spectroscopy, cranial ultrasonography. These techniques pose unique overlapping challenges equitable representation research through sampling bias, technical constraints, limited accessibility, insufficient resources. The present article adds conversation around need improve inclusivity by highlighting modality-specific historical current obstacles ongoing initiatives. We conclude discussing tangible solutions that transcend individual ultimately providing recommendations promote neuroscience.

Language: Английский

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The Neural Correlates of Response Inhibition across the Transition from Infancy to Toddlerhood: An fNIRS study

Imaging Neuroscience, Journal Year: 2024, Volume and Issue: 2, P. 1 - 21

Published: Jan. 1, 2024

Abstract The transition from late infancy into toddlerhood represents a fundamental period in early development. During this time, the prefrontal cortex (PFC) is undergoing structural and functional maturation processes that parallel emergence improvement of executive function skills, such as inhibitory control. Despite importance developmental period, relatively little known about development response inhibition, form control, associated neural substrates across key transition. Using near-infrared spectroscopy (fNIRS), an optical imaging technique suitable for developing brain, age-appropriate inhibition task, we investigated brain regions with 16-month-old toddlers. This pre-registered study extends our previous work 10-month-old infants (Fiske et al., 2022) it follows same cohort participants, now at 16 months age. Whilst demonstrated recruited right-lateralised PFC parietal when was required, current suggests by months, toddlers recruit left superior gyrus, right inferior frontal bilateral dorsolateral orbital cortex. Although there no longitudinal change performance, more widespread, were during compared 10 months. We acknowledge need replication these results. Nevertheless, findings suggest to may constitute important reorganisation might support control processes.

Language: Английский

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Lights on music cognition: A systematic and critical review of fNIRS applications and future perspectives

Brain and Cognition, Journal Year: 2024, Volume and Issue: 180, P. 106200 - 106200

Published: June 21, 2024

Research investigating the neural processes related to music perception and production constitutes a well-established field within cognitive neurosciences. While most neuroimaging tools have limitations in studying complexity of musical experiences, functional Near-Infrared Spectroscopy (fNIRS) represents promising, relatively new tool for both laboratory ecological settings, which is also suitable typical pathological populations across development. Here we systematically review fNIRS studies on cognition, highlighting prospects potentialities. We include an overview basic theory, together with brief comparison characteristics other tools. Fifty-nine meeting inclusion criteria (i.e., using as primary stimulus) are presented five thematic sections. Critical discussion methodology leads us propose guidelines good practices aiming robust signal analyses reproducibility. A continuously updated world map proposed, including information from criteria. It provides organized, accessible, updatable reference database, could serve catalyst future collaborations community. In conclusion, shows potential music, particularly contexts special populations, aligning current research priorities cognition.

Language: Английский

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Editorial: Advances in mobile optical brain activity monitoring

Frontiers in Neuroergonomics, Journal Year: 2025, Volume and Issue: 6

Published: March 7, 2025

much of this progress stems from constrained, single-snapshot experiments conducted in controlled laboratory settings. Understanding brain activity dynamic, complex, and multisensory real-world environments remains its infancy. Emerging mobile imaging technologies beyond electrocencephalography (EEG) (Nann et al., 2019), such as functional near-infrared spectroscopy (fNIRS) (Boas 2014) or diffuse optical tomography (DOT) (Chitnis 2016), are beginning to bridge gap, enabling continuous measurement cerebrovascular linked induced by, for example, human movement, perception, cognition, social communication, interaction naturalistic For instance, portable fNIRS devices have proven effective monitoring mental workload (Herff 2013;Park, 2023) can provide real-time feedback, e.g., the context brain-computer interface (BCI) applications (Soekadar 2021). In education, has been used study attention (Harrivel 2013), engagement (Verdiere 2018), learning outcomes (Lamb 2022) natural settings, while role infant development research expanded understanding perception cognition diverse populations (Gervain 2023). Moreover, hyperscanning (Hakim 2023;Scholkmann 2013) enables simultaneous multiple individuals, revealing mechanisms like inter-brain synchrony during interactions. Integrating with multimodal tools EEG (von Luhmann 2017), eye-tracking (Isbilir systemic physiological (Scholkmann enhances these insights, specifically into processes interpersonal dynamics, paving way towards new medical non-medical applications.The topic "Advances Mobile Optical Brain Activity Monitoring" underlines transformative potential related techniques investigating function dynamic Featuring eight contributions leading laboratories, collection highlights cutting-edge advancements field.In her review, Franziska Klein underscores critical importance spatial specificity signal quality applications, which vital reliable data neurofeedback BCI contexts (Klein, 2024). Challenges anatomical variability, variations cap placement, contamination by extracerebral noise motion artifacts addressed, advocating advanced preprocessing adaptive algorithms improve reproducibility reliability. Julie Bonnaire colleagues propose an innovative approach utilizing bond formation children (Bonnaire The integrates data, including conversational behaviors, rapport, collaborative tasks, synchrony. findings aim deepen connectivity informing design empathetic AI systems personalized educational that adapt group dynamics. Ryssa Moffat advocate longitudinal intergenerational studies uncover neural underlying dynamics across generations (Moffat By addressing ecological validity challenges designs protocols, perspective article interventions targeting relationships, particularly psychological contexts. Thibault Roumengous introduce NIRSense Aerie, a wearable system optimized high-G encountered military aircrew (Roumengous monitors oxygenation perfusion high-G-force exposure, offering feedback anti-G straining maneuver training operational safety. Future miniaturization comfort will extend other high-stress occupations. Katharina Lingelbach investigate workload-dependent hemispheric asymmetries emotion-cognition interactions using ecologically valid setup (Lingelbach Their reveal lateralized prefrontal cortex influenced emotional distractions levels, implications optimizing focus productivity work environments. Sruthi Srinivasan collaborators demonstrate incorporating subject-specific information enhance accuracy high-density (HD-DOT) (Srinivasan employing photogrammetry identify optode their shows localization errors, motor recordings ranged at 27.4mm average. collecting locations all NIRS achieve accurate results. Finally, Sabrina von Au examine activation patterns associated different self-touch identifying distinct hemodynamic responses phasic repetitive This activates orbitofrontal dorsolateral regions self-regulation, more strongly than self-touch, highlighting stronger self-regulatory selftouch, objective behavioral controls, need future on irregular environments.Besides underlining must be addressed drive field forward, illustrates technologies. While it is essential advance innovation instrumentation, analysis, experimental design, efforts also prioritize interdisciplinary collaborations fully realize promise exciting domain. Importantly, online brainstate-dependent sensory stimulation (Nasr human-computer (neuroadaptive technology, passive BCI) (Zander & Kothe, 2011), opportunities learning, well-being ergonomics. Establishing neurotech hubs ecosystems centered around robust academic-industry-clinical crucial facilitating rapid prototyping exploration solutions. context, imperative ensure neurotechnology serves enabler development, rather tool surveillance, coercion, any application undermines freedom rights (UNESCO, Embedding within neuroethical framework safeguard responsible use (Garden 2019). With efforts, offers bright future, redefining how we work, learn, interact digital

Language: Английский

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Neural indicators of numerical abilities in the infant human brain: A systematic review

Developmental Review, Journal Year: 2024, Volume and Issue: 74, P. 101150 - 101150

Published: Sept. 11, 2024

Language: Английский

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Simultaneous Eye Tracking and Cerebral Hemodynamic Monitoring in Infants: A Guide for Pediatric Outpatient Follow-Up

Brain Sciences, Journal Year: 2025, Volume and Issue: 15(5), P. 469 - 469

Published: April 28, 2025

Simultaneous eye tracking and cerebral hemodynamic monitoring contribute to the understanding of neural responses stimuli in infants. However, exploring impact complex socioeconomic environmental adversities on neurodevelopment requires transitioning this tool from research laboratories into clinical practice evaluate its feasibility outpatient contexts. Background/Objectives: This study aimed present a protocol for simultaneously integrating functional near-infrared spectroscopy (fNIRS) with (ET) infants at risk neurodevelopmental disorders setting limited resources, during cognitive task. Methods:The was applied their first 12 months life. The were exposed tasks involving processing social non-social stimuli, while brain signals monitored using fNIRS eyes tracked ET. included three main stages: (1) pre-collection, preparation habituation equipment setup (fNIRS ET); (2) function monitoring, assess preferential via ET; (3) post-collection, guidelines data pre-processing analysis. Results: application allowed identification technical challenges adaptation procedures use. methodological difficulty conventional cap, excessive movement, synchronization issues between ET, difficulties calibrating both devices across different age groups. Conclusions: standardization proposed enables healthcare professionals explore neurocognitive aspects pediatric settings expands scope assessments.

Language: Английский

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Special Section Guest Editorial: Thirty Years of Functional Near-Infrared Spectroscopy

Neurophotonics, Journal Year: 2023, Volume and Issue: 10(02)

Published: July 6, 2023

Functional Near-Infrared Spectroscopy (fNIRS) is a non-invasive optical technique that measures cerebral hemodynamics across multiple regions of interest, and thereby characterises brain functional activation. Since its first description in 1993, fNIRS has undergone substantial developments hardware, analysis techniques, applications. Thirty years later, this significantly enchancing our understanding diverse areas neuroscience research such as neurodevelopment, cognitive neuroscience, psychiatric disorders, neurodegenerative conditions, injury management intensive care settings. This special issue outlines the latest progress instrumentation techniques showcases some applications within expanding field over past decade.

Language: Английский

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Brain responses to repetition-based rule-learning do not exhibit sex differences: an aggregated analysis of infant fNIRS studies

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Jan. 31, 2024

Studies have repeatedly shown sex differences in some areas of language development, typically with an advantage for female over male children. However, the tested samples are small and effects do not always replicate. Here, we used a meta-analytic approach to address this issue larger sample, combining seven fNIRS studies on neural correlates repetition- non-repetition-based rule learning newborns 6-month-old infants. The ability extract structural regularities from speech input is fundamental it therefore highly relevant understand whether shows differences. meta-analysis effect Sex, as well other moderators infants' hemodynamic responses repetition-based (e.g. ABB: "mubaba") ABC: "mubage") sequences both anatomically functionally defined regions interests. Our analyses did reveal any at birth or 6 months, suggesting that encode these robust across sexes. Interestingly, revealed moderator effects. Thus newborns, found greater involvement bilateral temporal compared frontal repetition non-repetition sequences. Further, elicited 6-month-olds than especially areas. When analyzing functional clusters HbR timetraces, right-left asymmetry newborn boys brain girls, which may be interpreted terms cerebral blood flow girls early life. We conclude extracting well-defined substrate present does exhibit

Language: Английский

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Early executive function development: The first three years

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 12 - 25

Published: March 6, 2024

Language: Английский

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The Brain Imaging for Global Health (BRIGHT) Project: Longitudinal cohort study protocol

Gates Open Research, Journal Year: 2023, Volume and Issue: 7, P. 126 - 126

Published: Oct. 18, 2023

There is a scarcity of prospective longitudinal research targeted at early postnatal life which maps developmental pathways early-stage processing and brain specialisation in the context adversity. Follow up from infancy into one-five year age range key, as it constitutes critical gap between infant childhood studies. Availability portable neuroimaging (functional near infrared spectroscopy (fNIRS) electroencephalography (EEG)) has enabled access to rural settings increasing diversity our sampling broadening include previously underrepresented ethnic-racial geographical groups low- middle- income countries (LMICs). The primary objective Brain Imaging for Global Health (BRIGHT) project was establish function - using data mother for-age reference curves dyads living UK Gambia investigate association context-associated moderators trajectories across first two years Gambia. In total, 265 participating families were seen during pregnancy, 7–14 days, 1-, 5-, 8-, 12-, 18- 24-months post-partum. An additional visit now underway 3–5 assess pre-school outcomes. majority Gambian cohort live poverty, but while resource-poor many factors they commonly experience rich beneficial family caregiving with multigenerational care close-knit supportive community. Understanding impact different play such an environment (i.e., detrimental undernutrition versus support) will (i) improve representativeness models general cognitive birth, (ii) identify causal altered associated adversity both individual group level, (iii) (i.e. social context) that protect development despite presence poverty-associated challenges. This turn contribute interventions.

Language: Английский

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