An optimized luciferin formulation for NanoLuc-based in vivo bioluminescence imaging

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: April 15, 2025

Language: Английский

Modern tumor imaging models for rodents: potential and prospects in translational medicine

Bulletin of Russian State Medical University, Journal Year: 2025, Volume and Issue: 2025(2)

Published: March 1, 2025

Rodent neoplastic process models are extensively used in pre-clinical practice to assess the dynamics of tumor development and test anti-cancer drugs, which ensures flexibility choosing both basic advanced personalized for researchers. Various modern model imaging methods considered, including fluorescence bioluminescence imaging, enable comprehensive assessment, from qualitative evaluation vivo monitoring. We believe that autonomous bioluminescent systems mammalian cells will provide new possibilities noninvasive animal physiological processes, long-term monitoring progression.

Language: Английский

De novo luciferases enable multiplexed bioluminescence imaging

Chem, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024