Lab-on-Skin: A Review of Flexible and Stretchable Electronics for Wearable Health Monitoring

ACS Nano, Journal Year: 2017, Volume and Issue: 11(10), P. 9614 - 9635

Published: Sept. 13, 2017

Skin is the largest organ of human body, and it offers a diagnostic interface rich with vital biological signals from inner organs, blood vessels, muscles, dermis/epidermis. Soft, flexible, stretchable electronic devices provide novel platform to soft tissues for robotic feedback control, regenerative medicine, continuous health monitoring. Here, we introduce term "lab-on-skin" describe set that have physical properties, such as thickness, thermal mass, elastic modulus, water-vapor permeability, which resemble those skin. These can conformally laminate on epidermis mitigate motion artifacts mismatches in mechanical properties created by conventional, rigid electronics while simultaneously providing accurate, non-invasive, long-term, Recent progress design fabrication sensors more advanced capabilities enhanced reliability suggest an impending translation these research lab clinical environments. Regarding advances, first part this manuscript reviews materials, strategies, powering systems used electronics. Next, paper provides overview applications cardiology, dermatology, electrophysiology, sweat diagnostics, emphasis how may replace conventional tools. The review concludes outlook current challenges opportunities future directions wearable

Language: Английский

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Bio-Integrated Wearable Systems: A Comprehensive Review

Chemical Reviews, Journal Year: 2019, Volume and Issue: 119(8), P. 5461 - 5533

Published: Jan. 28, 2019

Bio-integrated wearable systems can measure a broad range of biophysical, biochemical, and environmental signals to provide critical insights into overall health status quantify human performance. Recent advances in material science, chemical analysis techniques, device designs, assembly methods form the foundations for uniquely differentiated type technology, characterized by noninvasive, intimate integration with soft, curved, time-dynamic surfaces body. This review summarizes latest this emerging field "bio-integrated" technologies comprehensive manner that connects fundamental developments chemistry, engineering sensing have potential widespread deployment societal benefit care. An introduction chemistries materials active components these contextualizes essential design considerations sensors associated platforms appear following sections. The subsequent content highlights most advanced biosensors, classified according their ability capture information. Additional sections feature schemes electrically powering strategies achieving fully integrated, wireless systems. concludes an overview key remaining challenges summary opportunities where chemistry will be critically important continued progress.

Language: Английский

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Wearable sensors: modalities, challenges, and prospects

Lab on a Chip, Journal Year: 2017, Volume and Issue: 18(2), P. 217 - 248

Published: Nov. 28, 2017

Wearable sensors have recently seen a large increase in both research and commercialization. However, success wearable has been mix of progress setbacks. Most commercial smart adaptation existing mechanical, electrical optical methods measuring the body. This involved innovations how to miniaturize sensing technologies, make them conformal flexible, development companion software that increases value measured data. chemical modalities experienced greater challenges adoption, especially for non-invasive sensors. There also significant making fundamental improvements electrical, modalities, improving their specificity detection. Many these can be understood by appreciating body's surface (skin) as more an information barrier than source. With deeper understanding faced state-of-the-art sensor technology, roadmap becomes clearer creating next generation breakthroughs.

Language: Английский

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Untethered soft robotics

Nature Electronics, Journal Year: 2018, Volume and Issue: 1(2), P. 102 - 112

Published: Feb. 8, 2018

Language: Английский

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Skin-integrated wireless haptic interfaces for virtual and augmented reality

Nature, Journal Year: 2019, Volume and Issue: 575(7783), P. 473 - 479

Published: Nov. 20, 2019

Language: Английский

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Smart Textiles for Electricity Generation

Chemical Reviews, Journal Year: 2020, Volume and Issue: 120(8), P. 3668 - 3720

Published: March 23, 2020

Textiles have been concomitant of human civilization for thousands years. With the advances in chemistry and materials, integrating textiles with energy harvesters will provide a sustainable, environmentally friendly, pervasive, wearable solution distributed on-body electronics era Internet Things. This article comprehensively thoughtfully reviews research activities regarding utilization smart harvesting from renewable sources on body its surroundings. Specifically, we start brief introduction to contextualize significance light emerging crisis, environmental pollution, public health. Next, systematically review according their abilities harvest biomechanical energy, heat biochemical solar as well hybrid forms energy. Finally, critical analysis insights into remaining challenges future directions. worldwide efforts, innovations materials elaborated this push forward frontiers textiles, which soon revolutionize our lives

Language: Английский

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Monitoring of the central blood pressure waveform via a conformal ultrasonic device

Nature Biomedical Engineering, Journal Year: 2018, Volume and Issue: 2(9), P. 687 - 695

Published: Sept. 4, 2018

Language: Английский

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Light in diagnosis, therapy and surgery

Nature Biomedical Engineering, Journal Year: 2017, Volume and Issue: 1(1)

Published: Jan. 10, 2017

Language: Английский

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Graphene Electronic Tattoo Sensors

ACS Nano, Journal Year: 2017, Volume and Issue: 11(8), P. 7634 - 7641

Published: July 18, 2017

Tattoo-like epidermal sensors are an emerging class of truly wearable electronics, owing to their thinness and softness. While most them based on thin metal films, a silicon membrane, or nanoparticle-based printable inks, we report sub-micrometer thick, multimodal electronic tattoo that made graphene. The graphene (GET) is designed as filamentary serpentines fabricated by cost- time-effective “wet transfer, dry patterning” method. It has total thickness 463 ± 30 nm, optical transparency ∼85%, stretchability more than 40%. GET can be directly laminated human skin just like temporary fully conform the microscopic morphology surface via van der Waals forces. open-mesh structure makes it breathable its stiffness negligible. A bare able stay attached for several hours without fracture delamination. With liquid bandage coverage, may functional up days. As electrode, GET–skin interface impedance par with medically used silver/silver-chloride (Ag/AgCl) gel electrodes, while offering superior comfort, mobility, reliability. been successfully applied measure electrocardiogram (ECG), electromyogram (EMG), electroencephalogram (EEG), temperature, hydration.

Language: Английский

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Soft, smart contact lenses with integrations of wireless circuits, glucose sensors, and displays

Science Advances, Journal Year: 2018, Volume and Issue: 4(1)

Published: Jan. 5, 2018

This study presents a soft, smart contact lens that provides real-time sensing for diabetes through wireless display.

Language: Английский

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