Technology Roadmap for Flexible Sensors

ACS Nano, Journal Year: 2023, Volume and Issue: 17(6), P. 5211 - 5295

Published: March 9, 2023

Humans rely increasingly on sensors to address grand challenges and improve quality of life in the era digitalization big data. For ubiquitous sensing, flexible are developed overcome limitations conventional rigid counterparts. Despite rapid advancement bench-side research over last decade, market adoption remains limited. To ease expedite their deployment, here, we identify bottlenecks hindering maturation propose promising solutions. We first analyze achieving satisfactory sensing performance for real-world applications then summarize issues compatible sensor-biology interfaces, followed by brief discussions powering connecting sensor networks. Issues en route commercialization sustainable growth sector also analyzed, highlighting environmental concerns emphasizing nontechnical such as business, regulatory, ethical considerations. Additionally, look at future intelligent sensors. In proposing a comprehensive roadmap, hope steer efforts towards common goals guide coordinated development strategies from disparate communities. Through collaborative efforts, scientific breakthroughs can be made sooner capitalized betterment humanity.

Language: Английский

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Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity

Signal Transduction and Targeted Therapy, Journal Year: 2021, Volume and Issue: 6(1)

Published: Dec. 16, 2021

Hydrogel is a type of versatile platform with various biomedical applications after rational structure and functional design that leverages on material engineering to modulate its physicochemical properties (e.g., stiffness, pore size, viscoelasticity, microarchitecture, degradability, ligand presentation, stimulus-responsive properties, etc.) influence cell signaling cascades fate. In the past few decades, plethora pioneering studies have been implemented explore cell-hydrogel matrix interactions figure out underlying mechanisms, paving way lab-to-clinic translation hydrogel-based therapies. this review, we first introduced hydrogels their fabrication approaches concisely. Subsequently, comprehensive description deep discussion were elucidated, wherein influences different behaviors cellular events highlighted. These or included integrin clustering, focal adhesion (FA) complex accumulation activation, cytoskeleton rearrangement, protein cyto-nuclei shuttling activation Yes-associated (YAP), catenin, etc.), compartment reorganization, gene expression, further biology modulation spreading, migration, proliferation, lineage commitment, etc.). Based them, current in vitro vivo hydrogel mainly covered diseases models, delivery protocols for tissue regeneration disease therapy, smart drug carrier, bioimaging, biosensor, conductive wearable/implantable biodevices, etc. summarized discussed. More significantly, clinical potential trials presented, accompanied which remaining challenges future perspectives field emphasized. Collectively, insights review will shed light principles new understand processes, are available providing significant indications serving broad range applications.

Language: Английский

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Rational Design of Immunomodulatory Hydrogels for Chronic Wound Healing

Advanced Materials, Journal Year: 2021, Volume and Issue: 33(39)

Published: July 12, 2021

With all the advances in tissue engineering for construction of fully functional skin tissue, complete regeneration chronic wounds is still challenging. Since immune reaction to damage critical regulating both quality and duration wound healing cascade, strategies modulate system are importance. Generally, response an injury, macrophages switch from pro-inflammatory anti-inflammatory phenotype. Therefore, controlling macrophages' polarization has become appealing approach regenerative medicine. Recently, hydrogels-based constructs, incorporated with various cellular molecular signals, have been developed utilized adjust cell functions stages healing. Here, current state knowledge on during first discussed. Recent advanced technologies used design immunomodulatory hydrogels then summarized. Rational providing controlled stimulation via hydrogel chemistry surface modification, as well incorporation molecules, also dicussed. In addition, effects hydrogels' properties immunogenic features process Finally, future directions upcoming research control responses highlighted.

Language: Английский

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Flexible MXene‐Based Composites for Wearable Devices

Advanced Functional Materials, Journal Year: 2021, Volume and Issue: 31(22)

Published: March 8, 2021

Abstract In recent decades, flexible and wearable devices have been extensively investigated due to their promising applications in portable mobile electronics human motion monitoring. MXene, a novel growing family of 2D nanomaterials, demonstrates superiorities such as outstanding electrical conductivity, abundant terminal groups, unique layered‐structure, large surface area, hydrophilicity, making it be potential candidate material for devices. Numerous pioneering works are devoted develop MXene‐based composites with various functions designed structures. Therefore, the latest progress is summarized this review, focusing on preparation strategies, working mechanisms, performances, sensors, supercapacitors, electromagnetic interference shielding materials. Moreover, current challenges future outlooks also discussed.

Language: Английский

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A Flexible Multifunctional Triboelectric Nanogenerator Based on MXene/PVA Hydrogel

Advanced Functional Materials, Journal Year: 2021, Volume and Issue: 31(38)

Published: July 4, 2021

Abstract Triboelectric nanogenerators (TENGs) represent an emerging technology in energy harvesting, medical treatment, and information technology. Flexible, portable, self‐powered electronic devices based on TENGs are much desired, whereas the complex preparation processes high cost of traditional flexible electrodes hinder their practical applications. Here, MXene/polyvinyl alcohol (PVA) hydrogel TENG (MH‐TENG) is presented with simple fabrication, output performance, versatile The doping MXene nanosheets promotes crosslinking PVA improves stretchability composite hydrogel. also form microchannels surfaces, which not only enhances conductivity by improving transport ions but generates extra triboelectric via a streaming vibration potential mechanism. measured open‐circuit voltage MH‐TENG reaches up to 230 V even single‐electrode mode. can be stretched 200% original length demonstrates monotonical increasing relationship between stretchable short‐circuit voltage. By utilizing MH‐TENG's outstanding property ultrahigh sensitivity mechanical stimuli, applications wearable movement monitoring, high‐precision written stroke recognition, low‐frequency harvesting demonstrated.

Language: Английский

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2D Heterostructures for Ubiquitous Electronics and Optoelectronics: Principles, Opportunities, and Challenges

Chemical Reviews, Journal Year: 2022, Volume and Issue: 122(6), P. 6514 - 6613

Published: Feb. 8, 2022

A grand family of two-dimensional (2D) materials and their heterostructures have been discovered through the extensive experimental theoretical efforts chemists, material scientists, physicists, technologists. These pioneering works contribute to realizing fundamental platforms explore analyze new physical/chemical properties technological phenomena at micro-nano-pico scales. Engineering 2D van der Waals (vdW) via chemical physical methods with a suitable choice stacking order, thickness, interlayer interactions enable exotic carrier dynamics, showing potential in high-frequency electronics, broadband optoelectronics, low-power neuromorphic computing, ubiquitous electronics. This comprehensive review addresses recent advances terms representative materials, general fabrication methods, characterization techniques vital role parameters affecting quality heterostructures. The main emphasis is on 3D-bulk (3D) hybrid systems exhibiting intrinsic quantum mechanical responses optical, valley, topological states. Finally, we discuss universality applications trends for future electronics optoelectronics (FEO) under challenges opportunities from physical, nanotechnological, synthesis perspectives.

Language: Английский

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Recent Progress in Essential Functions of Soft Electronic Skin

Advanced Functional Materials, Journal Year: 2021, Volume and Issue: 31(42)

Published: July 20, 2021

Abstract Inspired by the human skin, electronic skins (e‐skins) composed of various flexible sensors, such as strain sensor, pressure shear force temperature and humility delicate circuits, are emerged to mimic sensing functions skins. In this review, strategies realize versatile functionalities natural skin‐like e‐skins, including strain‐, pressure‐, force‐, temperature‐ humility‐sensing abilities, well self‐healing ability other summarized. Some representative examples high‐performance e‐skins their applications outlined discussed. Finally, outlook future is presented.

Language: Английский

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Flexible Accelerated‐Wound‐Healing Antibacterial MXene‐Based Epidermic Sensor for Intelligent Wearable Human‐Machine Interaction

Advanced Functional Materials, Journal Year: 2022, Volume and Issue: 32(47)

Published: Sept. 17, 2022

Abstract Flexible epidermic sensors made from conductive hydrogels are holding bright potential in personalized healthcare, multifunctional electronic skins, and human‐machine interfaces. However, it is still a great challenge to simultaneously realize hydrogel‐based with reliable self‐healing ability remarkable sensing performances high‐performance healthcare (especially electrophysiological signals) for wearable interaction, as well accelerated wound healing subsequent medical treatment together. Herein, flexible healable sensor assembled the facilely prepared antibacterial MXene hydrogel efficiently sensitively interaction. The as‐prepared possesses enhanced mechanical performance, outstanding capability, injectability, facile degradability, excellent biocompatibility, robust ability, which capable of being into monitor human movements rehabilitation training, detect tiny signals diagnosis cardiovascular‐ muscle‐related diseases, be employed In addition, can utilized treat infection effectively accelerate healing. Thus, sheds light on preparing integration personal health smart interaction next‐generation artificial skins.

Language: Английский

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Two‐dimensional MXenes: New frontier of wearable and flexible electronics

InfoMat, Journal Year: 2022, Volume and Issue: 4(4)

Published: Feb. 22, 2022

Abstract Wearable electronics offer incredible benefits in mobile healthcare monitoring, sensing, portable energy harvesting and storage, human‐machine interactions, etc., due to the evolution of rigid structure flexible stretchable devices. Lately, transition metal carbides nitrides (MXenes) are highly regarded as a group thriving two‐dimensional nanomaterials extraordinary building blocks for emerging platforms because their excellent electrical conductivity, enriched surface functionalities, large area. This article reviews most recent developments MXene‐enabled wearable electronics. Several electronic devices designed on nanometric scale highlighted by drawing attention widely developed nonstructural attributes, including 3D configured devices, textile planer substrates, bioinspired structures, printed materials. Furthermore, unique progress these nanodevices is representative applications healthcare, energy, electromagnetic interference (EMI) shielding, humanoid control machines. The prospects MXene key frontier next‐generation envisioned design challenges systems also discussed, followed proposed solutions. image

Language: Английский

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Stretchable and Conductive Composite Structural Color Hydrogel Films as Bionic Electronic Skins

Advanced Science, Journal Year: 2021, Volume and Issue: 8(20)

Published: Aug. 26, 2021

Electronic skins have received increasing attention in biomedical areas. Current efforts about electronic are focused on the development of multifunctional materials to improve their performance. Here, authors propose a novel natural-synthetic polymers composite structural color hydrogel film with high stretchability, flexibility, conductivity, and superior self-reporting ability construct ideal multiple-signal bionic skins. The is prepared by using mixture polyacrylamide (PAM), silk fibroin (SF), poly(3,4-ethylenedioxythiophene):poly (4-styrene sulfonate) (PEDOT:PSS, PP), graphene oxide (GO) replicate colloidal crystal templates inverse opal scaffolds, followed subsequent acid treatment. Due these specific structures components, resultant imparted vivid conductivity while retaining hydrogel's original stretchability flexibility. demonstrate that has obvious variation electromechanical properties during stretching bending process, which could thus be utilized as multi-signal response skin realize real-time sensing electrical human motions. These features indicate proposed can widen practical value

Language: Английский

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