Innovations in Tactile Sensing: Microstructural Designs for Superior Flexible Sensor Performance DOI

Guancheng Wu,

Xiang Li, Rongrong Bao

et al.

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: 34(44)

Published: June 22, 2024

Abstract Tactile sensors have garnered considerable interest for their capacity to detect and quantify tactile information. The incorporation of microstructural designs into flexible has emerged as a potent strategy augment sensitivity pressure variations, thereby enhancing linearity, response spectrum, mechanical robustness. This review underscores the imperative progress in microstructured sensors. Subsequently, discourse transitions prevalent materials employed fabrication sensor electrodes, encapsulation layers, active sensing mediums, elucidating merits limitations. In‐depth discussions are devoted adorned with microstructures, including but not limited to, micropyramids, microhemispheres, micropillars, microporous configurations, microcracks, topological interconnections, multilevel constructs, random roughness, biomimetic microstructures inspired by flora fauna, accompanied exemplar studies from each category. Moreover, utility within realm intelligent environments is explicated, highlighting application monitoring physiological signals, detection sliding motions, discernment surface textures. culminates critical examination paramount challenges predicaments that must be surmounted further development enhance functional performance sensors, paving way integration advanced sensory systems.

Language: Английский

Toxicity and Biocompatibility of Liquid Metals DOI
Sen Chen, Ruiqi Zhao, Xuyang Sun

et al.

Advanced Healthcare Materials, Journal Year: 2022, Volume and Issue: 12(3)

Published: Oct. 31, 2022

Abstract Recently, room‐temperature liquid metals have attracted increasing attention from researchers owing to their excellent material properties. Systematic interpretation of the potential toxicity issues involved is essential for a wide range applications, especially in biomedical and healthcare fields. However, even with exponential growth related studies, investigation toxicological impact possible hazards organisms still its infancy. This review aims provide comprehensive summary current frontier knowledge on metal toxicology biocompatibility different environments. Based recent this focuses Ga Bi‐based states. It necessary evaluate considering rapid increase research utilization such composites. Finally, existing challenges are discussed suggestions provided further clarify mechanisms strategies avoid adverse effects. In addition resolving doubts public concern about metals, expected promote healthy sustainable development metal‐based materials use diverse areas, those health care.

Language: Английский

Citations

94
A fully integrated, standalone stretchable device platform with in-sensor adaptive machine learning for rehabilitation DOI Creative Commons
Hongcheng Xu, Weihao Zheng, Yang Zhang

et al.

Nature Communications, Journal Year: 2023, Volume and Issue: 14(1)

Published: Nov. 27, 2023

Language: Английский

Citations

89
Achieving tissue-level softness on stretchable electronics through a generalizable soft interlayer design DOI Creative Commons
Yang Li, Nan Li, Wei Liu

et al.

Nature Communications, Journal Year: 2023, Volume and Issue: 14(1)

Published: July 26, 2023

Abstract Soft and stretchable electronics have emerged as highly promising tools for biomedical diagnosis biological studies, they interface intimately with the human body other systems. Most electronic materials devices, however, still Young’s moduli orders of magnitude higher than soft bio-tissues, which limit their conformability long-term biocompatibility. Here, we present a design strategy interlayer allowing use existing relatively high to versatilely realize devices ultralow tissue-level moduli. We demonstrated transistor arrays active-matrix circuits below 10 kPa—over two lower current state art. Benefiting from increased irregular dynamic surfaces, ultrasoft device created realizes electrophysiological recording on an isolated heart adaptability, spatial stability, minimal influence ventricle pressure. In vivo biocompatibility tests also demonstrate benefit suppressing foreign-body responses implantation. With its general applicability diverse this soft-interlayer overcomes material-level limitation imparting softness variety bioelectronic devices.

Language: Английский

Citations

77
Skin-inspired soft bioelectronic materials, devices and systems DOI
Chuanzhen Zhao, Jaeho Park, Samuel E. Root

et al.

Nature Reviews Bioengineering, Journal Year: 2024, Volume and Issue: 2(8), P. 671 - 690

Published: June 17, 2024

Language: Английский

Citations

70
3D Printed Implantable Hydrogel Bioelectronics for Electrophysiological Monitoring and Electrical Modulation DOI
Fu‐Cheng Wang, Yuhua Xue,

Xingmei Chen

et al.

Advanced Functional Materials, Journal Year: 2023, Volume and Issue: 34(21)

Published: Dec. 21, 2023

Abstract Electronic devices based on conducting polymer hydrogels have emerged as one of the most promising implantable bioelectronics for electrophysiological monitoring and diagnosis a wide spectrum diseases, in light their distinct conductivity biocompatibility. However, hydrogels‐based are routinely fabricated through conventional techniques, which challenged by its intrinsic poor processability polymers, well essentially fragile biointerface, thus hampering rapid innovation application advanced bioelectronics. Here, 3D printable poly(3,4‐ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) is reported, featuring superior printability direct ink writing (DIW), tissue‐like mechanical compliance (Young's modulus 650 kPa), instant tough bioadhesion (interfacial toughness 200 J m −2 shear strength 120 highly‐tunable electrical properties, long‐term vitro vivo structural electrochemical robustness. Electro‐physiological studies rat heart models with normal or arrhythmic conditions highlight capabilities establishing conformal biointerface dynamic organs, allowing high‐precision spatiotemporary epicardial monitoring, modulation acute myocardial infarction (MI) model. These advances provide strategy to improve tissue‐electronics interfacing, could serve basis next generation toward healthcare medical therapies.

Language: Английский

Citations

68
Wet‐Adaptive Electronic Skin DOI
Fan Chen, Qiuna Zhuang, Yichun Ding

et al.

Advanced Materials, Journal Year: 2023, Volume and Issue: 35(49)

Published: Aug. 11, 2023

Skin electronics provides remarkable opportunities for non-invasive and long-term monitoring of a wide variety biophysical physiological signals that are closely related to health, medicine, human-machine interactions. Nevertheless, conventional skin fabricated on elastic thin films difficult adapt the wet microenvironments skin: Elastic non-permeable, which block perspiration; adhere skin; Most work underwater. Here, Wet-Adaptive Electronic (WADE-skin) is reported, consists next-to-skin wet-adhesive fibrous layer, next-to-air waterproof stretchable permeable liquid metal electrode layer. While electronic functionality determined by design, this WADE-skin simultaneously offers superb stretchability, adhesion, permeability, biocompatibility, property. The can rapidly human after contact few seconds stably maintain adhesion over weeks even under conditions, without showing any negative effect health. use demonstrated stable recording electrocardiogram during intensive sweating as well underwater activities, strain sensor operation virtual reality-mediated

Language: Английский

Citations

66
Biological Tissue-Inspired Ultrasoft, Ultrathin, and Mechanically Enhanced Microfiber Composite Hydrogel for Flexible Bioelectronics DOI Creative Commons
Qiang Gao,

Fuqin Sun,

Yue Li

et al.

Nano-Micro Letters, Journal Year: 2023, Volume and Issue: 15(1)

Published: May 28, 2023

Hydrogels offer tissue-like softness, stretchability, fracture toughness, ionic conductivity, and compatibility with biological tissues, which make them promising candidates for fabricating flexible bioelectronics. A soft hydrogel film offers an ideal interface to directly bridge thin-film electronics the tissues. However, it remains difficult fabricate a ultrathin configuration excellent mechanical strength. Here we report tissue-inspired ultrasoft microfiber composite (< 5 μm) film, is currently thinnest as far know. The embedded microfibers endow prominent strength (tensile stress ~ 6 MPa) anti-tearing property. Moreover, our capability of tunable properties in broad range, allowing matching modulus most tissues organs. incorporation glycerol salt ions imparts high conductivity anti-dehydration behavior. Such hydrogels are constructing attaching-type bioelectronics monitor biosignals.

Language: Английский

Citations

65
Solvent‐Free and Skin‐Like Supramolecular Ion‐Conductive Elastomers with Versatile Processability for Multifunctional Ionic Tattoos and On‐Skin Bioelectronics DOI Open Access

Wenwen Niu,

Qiong Tian, Zhiyuan Liu

et al.

Advanced Materials, Journal Year: 2023, Volume and Issue: 35(39)

Published: June 24, 2023

The development of stable and biocompatible soft ionic conductors, alternatives to hydrogels ionogels, will open up new avenues for the construction stretchable electronics. Here, a brand-new design, encapsulating naturally occurring ionizable compound by polymer via high-density hydrogen bonds, resulting in solvent-free supramolecular ion-conductive elastomer (SF-supra-ICE) that eliminates dehydration problem possesses excellent biocompatibility, is reported. SF-supra-ICE with high conductivity (>3.3 × 10-2 S m-1 ) exhibits skin-like softness strain-stiffening behaviors, elasticity, breathability, self-adhesiveness. Importantly, can be obtained simple water evaporation step solidify aqueous precursor into nature. Therefore, act as inks painted printed customized tattoos (I-tattoos) multifunctional on-skin bioelectronics. I-tattoos exhibit ultraconformal seamless contact human skin, enabling long-term high-fidelity recording various electrophysiological signals extraordinary immunity motion artifacts. Human-machine interactions are achieved exploiting transmit beings. Stretchable I-tattoo electrode arrays, manufactured printing method, demonstrated multichannel digital diagnosis health condition back muscles spine.

Language: Английский

Citations

65
Liquid Metal Patterning and Unique Properties for Next‐Generation Soft Electronics DOI Creative Commons
Minwoo Kim, Hyungjun Lim, Seung Hwan Ko

et al.

Advanced Science, Journal Year: 2023, Volume and Issue: 10(6)

Published: Jan. 15, 2023

Room-temperature liquid metal (LM)-based electronics is expected to bring advancements in future soft owing its conductivity, conformability, stretchability, and biocompatibility. However, various difficulties arise when patterning LM because of rheological features such as fluidity surface tension. Numerous attempts are made overcome these difficulties, resulting LM-patterning methods. An appropriate choice method based on comprehensive understanding necessary fully utilize the unique properties. Therefore, authors aim provide thorough knowledge about methods properties for LM-based electronics. First, essential considerations investigated. Then, methods-serial-patterning, parallel-patterning, intermetallic bond-assisted patterning, molding/microfluidic injection-are categorized Finally, perspectives with provided. They include outstanding biocompatibility, permeability, restorability, recyclability. Also, they areas radio frequency electronics, robots, heterogeneous catalyst. devices permeate daily lives if aforementioned analyzed utilized.

Language: Английский

Citations

64
Soft bioelectronics for the management of cardiovascular diseases DOI
Sung‐Hyuk Sunwoo, Sang Ihn Han, Chan Soon Park

et al.

Nature Reviews Bioengineering, Journal Year: 2023, Volume and Issue: 2(1), P. 8 - 24

Published: Sept. 29, 2023

Language: Английский

Citations

59