Reliability of human cortical organoid generation

Nature Methods, Journal Year: 2018, Volume and Issue: 16(1), P. 75 - 78

Published: Dec. 14, 2018

Language: Английский

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Generation of Functional Human 3D Cortico-Motor Assembloids

Cell, Journal Year: 2020, Volume and Issue: 183(7), P. 1913 - 1929.e26

Published: Dec. 1, 2020

Language: Английский

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Profiling Cell Type Abundance and Expression in Bulk Tissues with CIBERSORTx

Methods in molecular biology, Journal Year: 2020, Volume and Issue: unknown, P. 135 - 157

Published: Jan. 1, 2020

Language: Английский

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The first five years of single-cell cancer genomics and beyond

Genome Research, Journal Year: 2015, Volume and Issue: 25(10), P. 1499 - 1507

Published: Oct. 1, 2015

Single-cell sequencing (SCS) is a powerful new tool for investigating evolution and diversity in cancer understanding the role of rare cells tumor progression. These methods have begun to unravel key questions biology that been difficult address with bulk measurements. Over past five years, there has extraordinary progress technological developments research applications, but these efforts represent only tip iceberg. In coming SCS will greatly improve our invasion, metastasis, therapy resistance during tools also direct translational applications clinic, areas such as early detection, noninvasive monitoring, guiding targeted therapy. this perspective, I discuss made myriad unexplored still lie ahead medicine.

Language: Английский

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Unravelling biology and shifting paradigms in cancer with single-cell sequencing

Nature reviews. Cancer, Journal Year: 2017, Volume and Issue: 17(9), P. 557 - 569

Published: Aug. 24, 2017

Language: Английский

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