Neural correlates of modality-specific and modality-invariant object recognition in the perirhinal cortex DOI Creative Commons
Heung‐Yeol Lim, Inah Lee

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Nov. 21, 2023

Summary The perirhinal cortex (PER) supports multimodal object recognition, but how information of objects is integrated within the PER remains unknown. Here, we recorded single units while rats performed a PER-dependent object-recognition task. In this task, audiovisual cues were simultaneously (multimodally) or separately (unimodally) presented. We identified two types object-selective neurons in PER: crossmodal cells, showing constant firing patterns for an irrespective its modality, and unimodal preference specific modality. Unimodal cells further dissociated versions by modulating their rates according to modality condition. A population-decoding analysis confirmed that could perform both modality-invariant modality-specific decoding – former recognizing as same various conditions latter remembering experiences object.

Language: Английский

Primacy of vision shapes behavioral strategies and neural substrates of spatial navigation in marmoset hippocampus DOI Creative Commons
Diego Buitrago-Piza, Benjamin Corrigan, Roberto A. Gulli

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: May 14, 2024

Abstract The role of the hippocampus in spatial navigation has been primarily studied nocturnal mammals, such as rats, that lack many adaptations for daylight vision. Here we demonstrate during 3D navigation, common marmoset, a new world primate adapted to daylight, predominantly uses rapid head-gaze shifts visual exploration while remaining stationary. During active locomotion marmosets stabilize head, contrast rats use low-velocity head movements scan environment they locomote. Pyramidal neurons marmoset CA3/CA1 regions show mixed selectivity view, direction, and place. Exclusive place is scarce. Inhibitory interneurons are selective angular velocity translation speed. Finally, found theta phase resetting local field potential oscillations triggered by shifts. Our findings indicate their ecological niche modifying exploration/navigation strategies corresponding hippocampal specializations.

Language: Английский

Citations

17
Hippocampal coding of identity, sex, hierarchy, and affiliation in a social group of wild fruit bats DOI
Saikat Ray,

Itay Yona,

Nadav Elami

et al.

Science, Journal Year: 2025, Volume and Issue: 387(6733)

Published: Jan. 30, 2025

Social animals live in groups and interact volitionally complex ways. However, little is known about neural responses under such natural conditions. Here, we investigated hippocampal CA1 neurons a mixed-sex group of five to 10 freely behaving wild Egyptian fruit bats that lived continuously laboratory-based cave formed stable social network. In-flight, most place cells were socially modulated represented the identity sex conspecifics. Upon interactions, specific interaction types. During active observation, encoded bat’s own position head direction, together with position, multiple Identity-coding same bat across contexts. The strength coding was by sex, hierarchy, affiliation. Thus, form multidimensional sociospatial representation world.

Language: Английский

Citations

2
A theory of hippocampal function: New developments DOI Creative Commons
Edmund T. Rolls, Alessandro Treves

Progress in Neurobiology, Journal Year: 2024, Volume and Issue: 238, P. 102636 - 102636

Published: June 2, 2024

We develop further here the only quantitative theory of storage information in hippocampal episodic memory system and its recall back to neocortex. The is upgraded account for a revolution understanding spatial representations primate, including human, hippocampus, that go beyond place where individual located, location being viewed scene. This fundamental much primate navigation: functions supported humans by pathways build 'where' view feature combinations ventromedial visual cortical stream, separate from those 'what' object face inferior temporal cortex, reward orbitofrontal cortex. Key new computational developments include capacity CA3 attractor network storing whole charts space; how correlations inherent self-organizing continuous impact capacity; can combine discrete representations; roles rewards reach hippocampus later consolidation into long-term part via cholinergic cortex; ways analysing neocortical using Potts networks.

Language: Английский

Citations

12
Anthropoid origins and adaptations DOI

Susan Cachel

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

0
Monkeys can identify pictures from words DOI Creative Commons

Elizabeth Cabrera-Ruiz,

Marlen Alva,

Mario Treviño

et al.

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(2), P. e0317183 - e0317183

Published: Feb. 12, 2025

Humans learn and incorporate cross-modal associations between auditory visual objects (e.g., a spoken word picture) into language. However, whether nonhuman primates can words pictures remains uncertain. We trained two rhesus macaques in delayed match-to-sample task to determine they could sounds of different types. In each trial, the monkeys listened brief sound monkey vocalization or human word), retained information about match it with one 2–4 presented on touchscreen after 3-second delay. found that learned performed proficiently over dozen associations. addition, test their ability generalize, we exposed them uttered by individuals. hit rate remained high but more variable, suggesting perceived new as equivalent, though not identical. conclude types, retain working memory, generalize objects. These findings position an ideal model for future research brain pathways

Language: Английский

Citations

0
Advertisement vocalizations support home-range defense in the singing mouse DOI

Yuki Fujishima,

Michael A. Long

Current Biology, Journal Year: 2025, Volume and Issue: unknown

Published: May 1, 2025

Language: Английский

Citations

0
Long‐range projections of oxytocin neurons in the marmoset brain DOI Creative Commons
Arthur Lefèvre,

Jazlynn Meza,

Cory T. Miller

et al.

Journal of Neuroendocrinology, Journal Year: 2024, Volume and Issue: 36(6)

Published: April 24, 2024

Abstract The neurohormone oxytocin (OT) has become a major target for the development of novel therapeutic strategies to treat psychiatric disorders such as autism spectrum disorder because its integral role in governing many facets mammalian social behavior. Whereas extensive work rodents produced much our knowledge OT, we lack basic information about neurobiology primates making it difficult interpret limited effects that OT manipulations have had human patients. In fact, previous studies revealed only fibers primate brains. Here, investigated connectome marmoset using immunohistochemistry, and mapped throughout brains adult male female monkeys. We found projections reaching limbic cortical areas are involved regulation behaviors, amygdala, medial prefrontal cortex, basal ganglia. pattern observed marmosets is notably similar connectomes described rodents. Our findings here contrast with results by demonstrating broad distribution brain. Given prevalence this brain, methods developed manipulate endogenous likely be applicable marmosets.

Language: Английский

Citations

2
The Neural Dynamics of Familiar Face Recognition DOI Creative Commons
Holger Wiese, Stefan R. Schweinberger, Gyula Kovács

et al.

Neuroscience & Biobehavioral Reviews, Journal Year: 2024, Volume and Issue: 167, P. 105943 - 105943

Published: Nov. 16, 2024

Humans are highly efficient at recognising familiar faces. However, previous EEG/ERP research has given a partial and fragmented account of the neural basis this remarkable ability. We argue that is related to insufficient consideration fundamental characteristics face recognition. These include image-independence (recognition across different pictures), levels familiarity (familiar faces vary hugely in duration intensity our exposure them), automaticity (we cannot voluntarily withhold from face), domain-selectivity (the degree which effects selective). review recent work, combining uni- multivariate methods, systematically targeted these shortcomings. present theoretical recognition, dividing it into early visual, domain-sensitive domain-general phases, integrating familiarity. Our incorporates classic more concepts, such as multi-dimensional representation course-to-fine processing. While several questions remain be addressed, new represents major step forward understanding neurophysiological

Language: Английский

Citations

2
Sexual representation of social memory in the ventral CA1 neurons DOI Open Access
Akiyuki Watarai, Kentaro Tao, Teruhiro Okuyama

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: April 2, 2024

Abstract Recognizing familiar individuals is crucial for adaptive social interactions among animals. However, the multidimensional nature of memory encompassing sexual information remains unelucidated. We found that neurons in ventral CA1 region (vCA1) mouse hippocampus encoded identities and properties, specifically sex strain, conspecifics by using both rate theta-based temporal coding. Optogenetic reactivation memories females, but not males, induced place preference. Ablation upstream medial amygdala (MeA) or hippocampal dorsal CA2 (dCA2) disrupted representation dimorphism valence. Selective overlapping neural populations distinct female representing was sufficient to induce Thus, vCA1 employ dual coding schemes represent properties as a cohesive memory. One-Sentence Summary Social maps conspecifics.

Language: Английский

Citations

1
Neuronal Mechanisms Underlying Face Recognition in Non‐human Primates DOI Creative Commons
Hidetoshi Amita, Kenji W. Koyano, Jun Kunimatsu

et al.

Japanese Psychological Research, Journal Year: 2024, Volume and Issue: 66(4), P. 416 - 442

Published: June 10, 2024

Humans and primates rely on visual face recognition for social interactions. Damage to specific brain areas causes prosopagnosia, a condition characterized by the inability recognize familiar faces, indicating presence of specialized processing. A breakthrough finding came from non-human primate (NHP) study conducted in early 2000s; it was first identify multiple processing temporal lobe, termed patches. Subsequent studies have demonstrated unique role each patch structural analysis faces. More recent expanded these findings exploring networks memory functions importance exposure development system. In this review, we discuss neuronal mechanisms responsible analyzing facial features, categorizing associating faces with contexts within both cerebral cortex subcortical areas. Use NHPs neuropsychological neurophysiological can highlight mechanistic aspects circuit underlying at single-neuron whole-brain network levels.

Language: Английский

Citations

1