Metal-free Decarboxylative Oxygenation of α-Amino Acids to Amide Compounds via Photoredox Catalysis DOI
Rui Zhu,

Yaxin Wang,

Minshu Cui

et al.

Applied Catalysis A General, Journal Year: 2024, Volume and Issue: unknown, P. 120084 - 120084

Published: Dec. 1, 2024

Language: Английский

An automatic end-to-end chemical synthesis development platform powered by large language models DOI Creative Commons
Yixiang Ruan,

Chenyin Lu,

Ning Xu

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: Nov. 23, 2024

The rapid emergence of large language model (LLM) technology presents promising opportunities to facilitate the development synthetic reactions. In this work, we leveraged power GPT-4 build an LLM-based reaction framework (LLM-RDF) handle fundamental tasks involved throughout chemical synthesis development. LLM-RDF comprises six specialized agents, including Literature Scouter, Experiment Designer, Hardware Executor, Spectrum Analyzer, Separation Instructor, and Result Interpreter, which are pre-prompted accomplish designated tasks. A web application with as backend was built allow chemist users interact automated experimental platforms analyze results via natural language, thus, eliminating need for coding skills ensuring accessibility all chemists. We demonstrated capabilities in guiding end-to-end process copper/TEMPO catalyzed aerobic alcohol oxidation aldehyde reaction, literature search information extraction, substrate scope condition screening, kinetics study, optimization, scale-up product purification. Furthermore, LLM-RDF's broader applicability versability validated on various three distinct reactions (SNAr photoredox C-C cross-coupling heterogeneous photoelectrochemical reaction). rise offers new advancing synthesis. Here, authors developed copilot design

Language: Английский

Citations

10
Integrating P‐Doped Carbon Nitride Dots as Active Sites on P/Mo Co‐Doped BiVO4 Photoanodes Promotes H2O2 Production DOI
Yankun Wang, Yuntao Xu, Xirui Zhang

et al.

Small, Journal Year: 2025, Volume and Issue: unknown

Published: April 7, 2025

Abstract The indirect anthraquinone method is currently used to produce H 2 O , but it leads high energy consumption and a large amount of chemical waste. Alternatively, water oxidation reactions offer potential green approach for production, although constrained by low selectivity. Herein, the functional photoanodes are rationally designed production via photocatalytic oxidation. Specifically, P/Mo co‐doped BiVO 4 films achieved on conductive glass serve as layer, which coated with an ultrathin amorphous TiO film achieve good stability. Importantly, metal‐free P‐doped polymeric carbon nitride dots deposited photoanode, acting reaction centres. This innovative moves away from traditional reliance inorganic materials co‐catalysts in order suppress thermodynamically favoured O₂ evolution, which, turn, significantly enhances selectivity, efficiency stability H₂O₂ production. Consequently, optimal selectivity ≈64% at applied voltage bias 1.7 V versus RHE 1.0 m KHCO 3 solution, achieving yield ≈34.2 µmol hr −1 cm −2 . research offers novel strategy developing optimised photoanode synthesis.

Language: Английский

Citations

2
Unexpected piezoelectric properties of electrospun polyimide nanofibers for application in an extreme environment DOI

Liangkang Huang,

Jianwei Li,

Shuting Chen

et al.

Journal of Materials Chemistry C, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

The piezoelectric properties of FPI nanofibers were first discovered. This makes it a potential material for manufacturing wearable flexible electronic devices in extreme environments.

Language: Английский

Citations

8
Upgrading of nitrate to hydrazine through cascading electrocatalytic ammonia production with controllable N-N coupling DOI Creative Commons
Shunhan Jia, Libing Zhang,

Hanle Liu

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: Oct. 3, 2024

Language: Английский

Citations

7
Interfacial Hydrogen-Bond Network Regulation Tuned Water Dissociation Enables Selective Chlorination of Alkenes DOI
Junwei Yao, Chuanqi Cheng, Yongmeng Wu

et al.

Journal of the American Chemical Society, Journal Year: 2025, Volume and Issue: 147(9), P. 8024 - 8031

Published: Feb. 20, 2025

Electrocatalytically selective chlorination of olefins in Cl--containing solutions is a sustainable method for synthesizing chlorohydrin/vicinal dichloride; however, controlling the selectivity challenging. Here, aqueous/dimethyl carbonate (DMC) hybrid electrolytes with different H2O/DMC ratios are designed to modulate ·OH formation increase corresponding selectivities. The combined results in/ex situ spectroscopies and molecular dynamics simulations reveal origin high selectivity. TFSI- shields transportation free H2O provide moderate synthesis chlorohydrin. DMC reconstructs hydrogen bonds minimize interaction between them anode, matching requirements vicinal dichloride production. Thus, these not only achieve selectivities 80% 76% chlorohydrin dichloride, respectively, but also enable other isolated yields up 74%. This work provides facile strategy regulate anodic via rational electrolyte design.

Language: Английский

Citations

1
Strong adsorption enhances mass transfer and promotes efficient hydrolysis of cellulose to sugar by solid acids DOI

Chengqi Feng,

Yuewen Dai,

Chenkai Jin

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 279, P. 135060 - 135060

Published: Aug. 28, 2024

Language: Английский

Citations

4
Polyfluoroalkanoic Acids as Fluoroalkylating Reagents: Strategy for Direct Access to Rf-Embedded Amides DOI
Lalit Mohan Kabadwal,

Shuvojit Haldar,

Atanu Bera

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 2, 2025

Herein, we have reported the application of bench stable perfluoroalkanoic acids as fluoro-alkylating reagents in combination with DIB and primary amides for sequential one-pot transformation to R

Language: Английский

Citations

0
Accelerated flow synthesis of aripiprazole and brexpiprazole in environmentally benign solvents DOI Creative Commons
Bo Dong, Zheng Chen,

Hao Zhao

et al.

Green Synthesis and Catalysis, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

0
Electrochemical Conversion of Carboxylic Acids to Terminal Alkenes Enabled by Dialkyl Phosphate Electrolyte DOI Creative Commons

Tasuku Ito,

Xiongjie Jin, Kyoko Nozaki

et al.

Tetrahedron, Journal Year: 2025, Volume and Issue: 176, P. 134560 - 134560

Published: Feb. 24, 2025

Language: Английский

Citations

0
Photoelectrocatalytic Cl-mediated C(sp3)–H aminomethylation of hydrocarbons by BiVO4 photoanodes DOI Creative Commons

Anzai Shi,

Pengfei Xie, Yanwei Wang

et al.

Nature Communications, Journal Year: 2025, Volume and Issue: 16(1)

Published: March 8, 2025

Interfacial photoelectrochemistry at photoanodes has been extensively researched for solar energy conversion, but its application the production of high-value-added chemical compounds in organic chemistry still presents challenges. Herein, we report photoelectrocatalytic Cl-mediated C(sp3)–H aminomethylation alkanes with self-developed and reusable BiVO4 photoanodes. The swift condensation aniline aldehydes, along decrease electricity input by photogenerated holes photoanodes, work together to prevent excessive oxidation aniline, leading high yields desired product. Mechanistic experiments demonstrate that Cl- ions, as key mediators, could be attracted oxidized form Cl2. This is followed light-promoted homolytic cleavage Cl2, generating Cl radicals efficiently abstract hydrogen atoms from hydrocarbons. opens an avenue interfacial photoelectrochemical synthesis demonstrates a potential method optimizing conversion into fuels. A stable recyclable photoelectrode material was developed efficient hydrocarbons cell, which provides promising fuel conversion.

Language: Английский

Citations

0