The silent pandemic of stress: impact on menstrual cycle and ovulation DOI Creative Commons

Mariam Saadedine,

Sarah L. Berga, Stephanie S. Faubion

et al.

Stress, Journal Year: 2025, Volume and Issue: 28(1)

Published: Jan. 25, 2025

In the current age of technological advancement, stress has emerged as a silent pandemic affecting individuals, especially young generations, globally. Factors such increased competition, social pressures fueled by media and smartphones, sense diminished control in face modern challenges contribute to rising levels. addition negative implications on mental well-being, affects physiological processes menstrual cycle. Functional hypogonadotropic hypogonadism is spectrum ranging from regular cycles with short or insufficient luteal phases irregular cycles, oligomenorrhea, anovulation, complete amenorrhea, depending how variably disrupts gonadotropic-releasing hormone (GnRH) drive. hypothalamic amenorrhea (FHA), most severe manifestation, complex global neuroendocrinopathy several serious health consequences infertility. Concomitant include bone loss, endothelial dysfunction, cardiovascular risks. The collective burden underscores need for clinical awareness comprehensive treatment strategies addressing behavioral biopsychosocial stressors that lead chronic hypothalamic-pituitary-adrenal (HPA) axis activation. Despite its prevalence numerous adverse consequences, research this condition remains limited, revealing significant gap understanding condition. Larger long-term follow-up studies are important accurately assess FHA prevalence, intervention efficacy, recovery outcomes.

Language: Английский

The silent pandemic of stress: impact on menstrual cycle and ovulation DOI Creative Commons

Mariam Saadedine,

Sarah L. Berga, Stephanie S. Faubion

et al.

Stress, Journal Year: 2025, Volume and Issue: 28(1)

Published: Jan. 25, 2025

In the current age of technological advancement, stress has emerged as a silent pandemic affecting individuals, especially young generations, globally. Factors such increased competition, social pressures fueled by media and smartphones, sense diminished control in face modern challenges contribute to rising levels. addition negative implications on mental well-being, affects physiological processes menstrual cycle. Functional hypogonadotropic hypogonadism is spectrum ranging from regular cycles with short or insufficient luteal phases irregular cycles, oligomenorrhea, anovulation, complete amenorrhea, depending how variably disrupts gonadotropic-releasing hormone (GnRH) drive. hypothalamic amenorrhea (FHA), most severe manifestation, complex global neuroendocrinopathy several serious health consequences infertility. Concomitant include bone loss, endothelial dysfunction, cardiovascular risks. The collective burden underscores need for clinical awareness comprehensive treatment strategies addressing behavioral biopsychosocial stressors that lead chronic hypothalamic-pituitary-adrenal (HPA) axis activation. Despite its prevalence numerous adverse consequences, research this condition remains limited, revealing significant gap understanding condition. Larger long-term follow-up studies are important accurately assess FHA prevalence, intervention efficacy, recovery outcomes.

Language: Английский

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