Dopaminergic mechanisms of dynamical social specialization in mouse microsocieties DOI Creative Commons
Clément Prévost-Solié,

Anne Nicolson,

Robert Justo

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 11, 2025

Summary Social organization and division of labor are fundamental to animal societies, but how do these structures emerge from individual interactions, what role does neuromodulation play in shaping them? Using behavioral tracking a semi-natural environment, neural recordings, computational models integrating reinforcement social learning, we show that groups three isogenic mice spontaneously develop specialized roles while solving foraging task requiring decisions under constraints. Moreover, shaped by dopaminergic activity the ventral tegmental area. Strikingly, despite minor sex-differences behavior when were tested alone, male triads formed stable worker-scrounger relationships driven competition, whereas female adopted uniform, cooperative strategies. Model analysis revealed intra- inter-sex parameter differences resource exploitation, combined with contingent dynamic drive specialization division. Most notably, it highlighted contingency, amplified magnifies shapes profiles. The plastic, adaptive nature within was confirmed manipulating cell activity, which reshaped altered group structure. Our findings support feedback loop where context states, turn reinforce stabilize structures.

Language: Английский

Dopaminergic mechanisms of dynamical social specialization in mouse microsocieties DOI Creative Commons
Clément Prévost-Solié,

Anne Nicolson,

Robert Justo

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 11, 2025

Summary Social organization and division of labor are fundamental to animal societies, but how do these structures emerge from individual interactions, what role does neuromodulation play in shaping them? Using behavioral tracking a semi-natural environment, neural recordings, computational models integrating reinforcement social learning, we show that groups three isogenic mice spontaneously develop specialized roles while solving foraging task requiring decisions under constraints. Moreover, shaped by dopaminergic activity the ventral tegmental area. Strikingly, despite minor sex-differences behavior when were tested alone, male triads formed stable worker-scrounger relationships driven competition, whereas female adopted uniform, cooperative strategies. Model analysis revealed intra- inter-sex parameter differences resource exploitation, combined with contingent dynamic drive specialization division. Most notably, it highlighted contingency, amplified magnifies shapes profiles. The plastic, adaptive nature within was confirmed manipulating cell activity, which reshaped altered group structure. Our findings support feedback loop where context states, turn reinforce stabilize structures.

Language: Английский

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