Immunological Reviews,
Journal Year:
2021,
Volume and Issue:
303(1), P. 83 - 102
Published: July 30, 2021
Abstract
Most
antibodies
produced
in
the
body
are
of
IgA
class.
The
dominant
cell
population
producing
them
plasma
cells
within
lamina
propria
gastrointestinal
tract,
but
many
IgA‐producing
also
found
airways,
mammary
tissues,
urogenital
tract
and
inside
bone
marrow.
transported
into
lumen
by
epithelial
as
part
mucosal
secretions,
they
present
serum
other
fluids.
A
large
commensal
microbiota
gut
is
covered
with
antibodies,
it
has
been
demonstrated
that
this
plays
a
role
maintaining
healthy
balance
between
host
bacteria.
However,
play
important
roles
neutralizing
pathogens
upper
airways.
distinction
two
‐
protective
balance‐maintaining
not
only
implications
on
function
how
production
regulated.
Here,
we
discuss
these
issues
special
focus
Science Advances,
Journal Year:
2023,
Volume and Issue:
9(44)
Published: Nov. 1, 2023
The
constant
exposure
of
the
fish
branchial
cavity
to
aquatic
pathogens
causes
local
mucosal
immune
responses
be
extremely
important
for
their
survival.
Here,
we
used
a
marker
T
lymphocytes/natural
killer
(NK)
cells
(ZAP70)
and
advanced
imaging
techniques
investigate
lymphoid
architecture
zebrafish
cavity.
We
identified
sub-pharyngeal
organ,
which
tentatively
named
“Nemausean
organ”
(NELO).
NELO
is
enriched
in
T/NK
cells,
plasma/B
antigen-presenting
embedded
network
reticulated
epithelial
cells.
presence
activated
lymphocyte
proliferation,
but
not
V(D)J
recombination
or
hematopoiesis,
suggests
that
secondary
organ.
In
response
infection,
displays
structural
changes
including
formation
cell
clusters.
gill
tissues
form
cohesive
unit
within
large
network.
Collectively,
reveal
an
unreported
organ
reminiscent
mammalian
tonsils
evolved
multiple
teleost
families.
Fish & Shellfish Immunology,
Journal Year:
2020,
Volume and Issue:
107, P. 172 - 186
Published: Sept. 23, 2020
Increased
industrialized
production
of
salmonids
challenges
aspects
concerning
available
feed
resources
and
animal
welfare.
The
immune
system
plays
a
key
component
in
this
respect.
Novel
ingredients
may
trigger
unwarranted
responses
again
affecting
the
well-being
fish.
Here
we
review
our
current
knowledge
salmon
intestinal
anatomy,
immunity,
digestive
physiology
microbiota
context
feeding
regimes.
We
point
out
gaps
indicate
promising
novel
technologies
to
improve
salmonid
health.
Immunological Reviews,
Journal Year:
2021,
Volume and Issue:
303(1), P. 83 - 102
Published: July 30, 2021
Abstract
Most
antibodies
produced
in
the
body
are
of
IgA
class.
The
dominant
cell
population
producing
them
plasma
cells
within
lamina
propria
gastrointestinal
tract,
but
many
IgA‐producing
also
found
airways,
mammary
tissues,
urogenital
tract
and
inside
bone
marrow.
transported
into
lumen
by
epithelial
as
part
mucosal
secretions,
they
present
serum
other
fluids.
A
large
commensal
microbiota
gut
is
covered
with
antibodies,
it
has
been
demonstrated
that
this
plays
a
role
maintaining
healthy
balance
between
host
bacteria.
However,
play
important
roles
neutralizing
pathogens
upper
airways.
distinction
two
‐
protective
balance‐maintaining
not
only
implications
on
function
how
production
regulated.
Here,
we
discuss
these
issues
special
focus
