Uncovering the heterogeneity of the gut microbial taxa associated with the contents of different fatty acids in muscle with cecum luminal content and fecal samples from two pig populations DOI Creative Commons
Xiao Sun, Bin Yang, Congying Chen

et al.

Frontiers in Microbiology, Journal Year: 2025, Volume and Issue: 16

Published: April 30, 2025

Fatty acids in pork are involved cellular physiological functions and related to meat nutrition, tenderness, flavor. Increasing evidences have suggested that short-chain fatty produced by the gut microbiota may affect host metabolism energy utilization. However, association between long-chain (LCFAs) has been largely unknown. In this study, microbial compositions of 243 cecum content samples from Erhualian pigs 235 fecal Bamaxiang were determined high throughput 16S rRNA gene sequencing. The contents 12 LCFAs longissimus dorsi (LD) muscle also for all experimental both pig populations. We systematically evaluated contribution variations acid α -diversity microbiota, co-abundance groups (CAGs) Amplicon Sequence Variants (ASVs), acid-associated bacterial taxa. identified hundred ASVs > 40 taxa significantly associated with two Different numbers specific detected luminal samples, suggesting heterogeneity LCFA-associated locations. uncovered some interesting associations contents. strongest was observed ASV annotated Akkermansia n-6/n-3 polyunsaturated ratio ( p = 6.45E-04, Z −9.65). could explain 1.47–4.62% variation twelve acids. functional prediction analysis KEGG pathways metabolisms carbohydrate lipids, fat digestion absorption positively adipocytokine signaling pathway thermogenesis negatively results study provided basic knowledge improving regulating microbiome.

Language: Английский

Uncovering the heterogeneity of the gut microbial taxa associated with the contents of different fatty acids in muscle with cecum luminal content and fecal samples from two pig populations DOI Creative Commons
Xiao Sun, Bin Yang, Congying Chen

et al.

Frontiers in Microbiology, Journal Year: 2025, Volume and Issue: 16

Published: April 30, 2025

Fatty acids in pork are involved cellular physiological functions and related to meat nutrition, tenderness, flavor. Increasing evidences have suggested that short-chain fatty produced by the gut microbiota may affect host metabolism energy utilization. However, association between long-chain (LCFAs) has been largely unknown. In this study, microbial compositions of 243 cecum content samples from Erhualian pigs 235 fecal Bamaxiang were determined high throughput 16S rRNA gene sequencing. The contents 12 LCFAs longissimus dorsi (LD) muscle also for all experimental both pig populations. We systematically evaluated contribution variations acid α -diversity microbiota, co-abundance groups (CAGs) Amplicon Sequence Variants (ASVs), acid-associated bacterial taxa. identified hundred ASVs > 40 taxa significantly associated with two Different numbers specific detected luminal samples, suggesting heterogeneity LCFA-associated locations. uncovered some interesting associations contents. strongest was observed ASV annotated Akkermansia n-6/n-3 polyunsaturated ratio ( p = 6.45E-04, Z −9.65). could explain 1.47–4.62% variation twelve acids. functional prediction analysis KEGG pathways metabolisms carbohydrate lipids, fat digestion absorption positively adipocytokine signaling pathway thermogenesis negatively results study provided basic knowledge improving regulating microbiome.

Language: Английский

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