Diet, microbiome, and probiotics establish a crucial link in vaccine efficacy DOI Creative Commons
Soumam Dutta, Niloy Chatterjee, Nicholas L. F. Gallina

et al.

Critical Reviews in Microbiology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 26

Published: March 20, 2025

Vaccination plays a critical role in public health by reducing the incidence and prevalence of infectious diseases. The efficacy vaccine has numerous determinants, which include age, sex, genetics, environment, geographic location, nutritional status, maternal antibodies, prior exposure to pathogens. However, little is known about gut microbiome how it can be targeted through dietary interventions improve immunological responses. Unveiling this link imperative, particularly post-pandemic world, considering impaired COVID-19 response observed dysbiotic individuals. Therefore, article aims comprehensively review diet probiotics modulate composition, linked efficacy. Dietary fiber polyphenolic compounds derived from plant-based foods microbial diversity promoting growth short-chain fatty acids-producing microbes. On other hand, animal-based have mixed effects – whey protein fish oil promote eubiosis In contrast, lard red meat adverse effects. Studies further indicate that probiotic supplements exert varied effects, mostly strain dosage-specific. Interlinking diet, microbiome, probiotics, vaccines will reveal opportunities for newer research on diet-induced microbiome-manipulated precision vaccination strategies against

Language: Английский

Diet, microbiome, and probiotics establish a crucial link in vaccine efficacy DOI Creative Commons
Soumam Dutta, Niloy Chatterjee, Nicholas L. F. Gallina

et al.

Critical Reviews in Microbiology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 26

Published: March 20, 2025

Vaccination plays a critical role in public health by reducing the incidence and prevalence of infectious diseases. The efficacy vaccine has numerous determinants, which include age, sex, genetics, environment, geographic location, nutritional status, maternal antibodies, prior exposure to pathogens. However, little is known about gut microbiome how it can be targeted through dietary interventions improve immunological responses. Unveiling this link imperative, particularly post-pandemic world, considering impaired COVID-19 response observed dysbiotic individuals. Therefore, article aims comprehensively review diet probiotics modulate composition, linked efficacy. Dietary fiber polyphenolic compounds derived from plant-based foods microbial diversity promoting growth short-chain fatty acids-producing microbes. On other hand, animal-based have mixed effects – whey protein fish oil promote eubiosis In contrast, lard red meat adverse effects. Studies further indicate that probiotic supplements exert varied effects, mostly strain dosage-specific. Interlinking diet, microbiome, probiotics, vaccines will reveal opportunities for newer research on diet-induced microbiome-manipulated precision vaccination strategies against

Language: Английский

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