Genomic characteristics of emerging human pathogen Rickettsia aeschlimannii isolated from two Hyalomma tick species

iScience, Journal Year: 2025, Volume and Issue: 28(3), P. 112080 - 112080

Published: Feb. 21, 2025

Language: Английский

Equine piroplasmosis in different geographical areas in France: prevalence heterogeneity of asymptomatic carriers and low genetic diversity ofTheileria equiandBabesia caballi

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: July 26, 2024

Abstract Equine piroplasmosis is a worldwide tick-borne disease caused by the protozoan parasites Theileria equi and Babesia caballi , with significant economic sanitary consequences. It can also limit export of infected horses to piroplasmosis-free countries. These two are genetically variable, greater diversity observed in T. . This variability potentially impact diagnostic accuracy. Our study aimed evaluate frequency asymptomatic carriers these France describe circulating genotypes. We used species-specific nested PCR protocol targeting 18S small subunit (SSU) rRNA gene subsequent amplicon sequencing on blood samples collected from 566 across four National Veterinary Schools. The carrier varied considerably, ranging 18.7% around Paris (central-north) 56.1% Lyon (southeast), an overall prevalence 38.3%. were ten times more frequent (91.7%, 209/228 isolates) compared B. (8.8%, 19/228 isolates). Notably, was significantly lower northern region (Ile de France) southeastern regions. Interestingly, strong correlation between frequencies reported cases acute all geographic areas. Neither gender (female, gelding, or stallion) nor horse age showed effect carriers. In areas highest frequency, substantial proportion (22.2% 37.5%) carried before three, indicating high infection pressure. Genotyping 201 isolates revealed predominance genotype E (98%), only few belonging A (2%). detected originating Spain. All 19 belonged most common this species. discussion section explores link results, tick distribution abundance, detection febrile attributed piroplasmosis.

Language: Английский

Temporal dynamics of the Hyalomma marginatum-borne pathogens in southern France

Current Research in Parasitology and Vector-Borne Diseases, Journal Year: 2024, Volume and Issue: 6, P. 100213 - 100213

Published: Jan. 1, 2024

Language: Английский