Characteristics of Mycoplasma pneumoniae Pneumonia in Romanian Children DOI Creative Commons

Alexandru Ioan Ulmeanu,

Georgiana-Eugenia Ciuparu,

Elena Roxana Matran

et al.

Microorganisms, Journal Year: 2025, Volume and Issue: 13(4), P. 883 - 883

Published: April 11, 2025

Background/Objectives: Mycoplasma pneumoniae (M. pneumoniae), traditionally associated with mild community-acquired pneumonia in school-aged children, has experienced a delayed resurgence following the COVID-19 pandemic. The epidemiological and clinical characteristics of M. children within context this global have not been well established Romania. Materials Methods: This retrospective, single-center study analyzed diagnosed who were hospitalized pulmonology department “Grigore Alexandrescu” Emergency Hospital for Children Bucharest from March to December 2024. Clinical, laboratory, radiographic data extracted hospital records. infection was confirmed through polymerase chain reaction (PCR) multiplex panel detection or specific IgM antibody levels ≥ 10 AU/mL. Results: final analysis included 63 patients met inclusion criteria. cohort’s median age [IQR] 12.6 [8–15] years, 11.1% (n = 7) under 6 years old. findings revealed predominance right lung involvement (52.4%, n 33, p 0.03) significantly higher prevalence alveolar infiltrates compared interstitial patterns (88.9%, 56, < 0.001). Antibiotic choice did affect hospitalization duration. Pleural effusion emerged as common complication, occurring 27% 17) elevated admission leukocyte counts (p 0.007). Rare extrapulmonary manifestations meningoencephalitis (1.6%, 1) reactive infectious mucocutaneous eruption (3.2%, 2). Notably, co-infections other respiratory pathogens extend stays. Conclusions: contributes evolving profile infections post-pandemic era. It establishes foundation future multi-center analyses aimed at monitoring changing epidemiology presentations pediatric populations.

Language: Английский

Characteristics of Mycoplasma pneumoniae Pneumonia in Romanian Children DOI Creative Commons

Alexandru Ioan Ulmeanu,

Georgiana-Eugenia Ciuparu,

Elena Roxana Matran

et al.

Microorganisms, Journal Year: 2025, Volume and Issue: 13(4), P. 883 - 883

Published: April 11, 2025

Background/Objectives: Mycoplasma pneumoniae (M. pneumoniae), traditionally associated with mild community-acquired pneumonia in school-aged children, has experienced a delayed resurgence following the COVID-19 pandemic. The epidemiological and clinical characteristics of M. children within context this global have not been well established Romania. Materials Methods: This retrospective, single-center study analyzed diagnosed who were hospitalized pulmonology department “Grigore Alexandrescu” Emergency Hospital for Children Bucharest from March to December 2024. Clinical, laboratory, radiographic data extracted hospital records. infection was confirmed through polymerase chain reaction (PCR) multiplex panel detection or specific IgM antibody levels ≥ 10 AU/mL. Results: final analysis included 63 patients met inclusion criteria. cohort’s median age [IQR] 12.6 [8–15] years, 11.1% (n = 7) under 6 years old. findings revealed predominance right lung involvement (52.4%, n 33, p 0.03) significantly higher prevalence alveolar infiltrates compared interstitial patterns (88.9%, 56, < 0.001). Antibiotic choice did affect hospitalization duration. Pleural effusion emerged as common complication, occurring 27% 17) elevated admission leukocyte counts (p 0.007). Rare extrapulmonary manifestations meningoencephalitis (1.6%, 1) reactive infectious mucocutaneous eruption (3.2%, 2). Notably, co-infections other respiratory pathogens extend stays. Conclusions: contributes evolving profile infections post-pandemic era. It establishes foundation future multi-center analyses aimed at monitoring changing epidemiology presentations pediatric populations.

Language: Английский

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