Role of Tick Commensal Bacteria in the Propagation of Emerging Infectious Diseases: Data Gaps and One Health Implications DOI Creative Commons
Uday Turaga, Steven M. Presley

Zoonotic Diseases, Journal Year: 2024, Volume and Issue: 4(4), P. 283 - 292

Published: Nov. 7, 2024

Ticks are obligate hematophagous ectoparasites notorious for their role as vectors of pathogens that affect humans and animals, particularly relative to the propagation emerging infectious diseases (EIDs). Two important factors facilitating ticks in EIDs potential development resistance acaricides expansion nonindigenous tick species into new geographic regions. The acquisition acaricide enables populations be less susceptible vector control programs. Expansion distribution increases likelihood access host well pathogens. Understanding microbiome continues evolve, providing critical insights biology. largely comprises endosymbionts, pathogenic organisms, commensal bacteria. Endosymbionts highly preserved vertically transmitted from mother offspring, survival is recognized. Similarly, established. However, bacteria acquired environment while ingesting a blood meal. Because many spend most lifetime off hosts, it can assumed richness diversity variable dependent on ecosystem which exists. This mini-review identifies some data gaps relevant influence vectorial capacity ticks. As move habitats, locally playing adaptation habitat? Apart conventionally understood mechanisms ticks, influencing at population level?

Language: Английский

Exploring the microbiomes of camel ticks to infer vector competence: insights from tissue-level symbiont-pathogen relationships DOI Creative Commons
Rua Khogali, Armanda D. S. Bastos, Dennis Getange

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Feb. 15, 2025

Ticks are blood-feeding ectoparasites that harbor diverse pathogens and endosymbionts. Their microbial communities vary based on tick species, stage, sex, geographical location, surrounding environment, tissue type. Understanding microbiota at the level is crucial for unraveling how microbiomes distributed in tissues influence pathogen transmission. We used V1-V2 16 S rRNA gene sequencing to analyze tissue-specific bacterial compositions (hemolymph, saliva, salivary glands, midgut) of Amblyomma gemma, Rhipicephalus pulchellus, Hyalomma dromedarii, rufipes ticks collected from camels Marsabit County, northern Kenya. The region effectively differentiated 43 Rickettsia africae aeschlimannii samples other rickettsial as well Coxiella endosymbionts burnetii. In contrast, V3-V4 sequences these species could not be clearly distinguished. were most common Am. gemma Rh. while Francisella predominated ticks; both primarily localized glands. High abundances endosymbionts, Pseudomonas, associated with absence or low abundance suggesting competitive interactions between microbes. Additionally, Proteus mirabilis, an opportunistic urinary tract humans, was found predominantly ticks, except which abundant Furthermore, we detected Acinetobacter, Corynebacterium genera all tissues, supporting hypothesis bacteria might circulate camel blood ticks. Saliva hemolymph generally harbored more extracellular than glands midgut. This study provides a new approach unravel tick-endosymbiont-pathogen by examining localization tick-borne symbionts Hy. Our findings establish baseline developing understanding functional capacities designing symbiont-based control strategies.

Language: Английский

Citations

1
Genomic and Proteomic Analyses of Bacterial Communities of Ixodes scapularis Ticks from Broome County, New York DOI Creative Commons
Michel Shamoon‐Pour,

Emily H. Canessa,

Janet M. Macher

et al.

Microorganisms, Journal Year: 2025, Volume and Issue: 13(2), P. 258 - 258

Published: Jan. 24, 2025

The microbial communities of Ixodes scapularis, the primary vector Lyme disease in North America, exhibit regional variations that may affect pathogen transmission and competence. We analyzed bacterial I. scapularis ticks collected from Broome County, New York, using 16S rRNA gene sequencing (18 ticks) as well mass spectrometry-based proteomics (36 ticks). According to analysis, endosymbiont Rickettsia buchneri was most abundant species, with significantly higher (p = 0.0011) abundance females (54.76%) compared males (31.15%). detected Borreliella burgdorferi 44.44% Anaplasma phagocytophilum two nymphs but high relative abundances (12.73% 46.46%). Male exhibited diversity, although community composition showed no significant clustering by sex or life stage. Co-occurrence analysis revealed negative associations between R. Pseudomonas 0.0245), B. burgdorferi. Proteomic identified 12 buchneri-specific proteins, additionally detecting protozoan Babesia microti 18.18% females. These findings provide first comprehensive characterization microbiomes Southern Tier region York suggest broader distribution across tick stages than previously recognized, potential implications for dynamics.

Language: Английский

Citations

0
Molecular Detection of Anaplasma marginale in Amblyomma mixtum Infesting Cattle in the Major Livestock-Producing States of Mexico DOI Creative Commons

Carolina Cárdenas-Amaya,

Dora Romero–Salas, Marta Rafael

et al.

Pathogens, Journal Year: 2025, Volume and Issue: 14(3), P. 214 - 214

Published: Feb. 21, 2025

Bovine anaplasmosis is a tick-borne disease caused by Anaplasma marginale, although mechanical transmission biting flies also occurs. Infection with A. marginale can reach 26% mortality and morbidity associated reduced beef milk production, causing economic losses for livestock producers. Between March 2022 July 2023, 1920 ticks were collected from 52 cattle production units in major cattle-producing states Mexico, including Chiapas, Jalisco, Michoacán, Tabasco, Veracruz. Of all the collected, 35.57% morphologically identified as Amblyomma mixtum. Samples of mixtum each state, totaling 271, tested via polymerase chain reaction (PCR). was detected molecularly 15.3% samples. Chiapas had highest prevalence (24.0%), followed Tabasco Veracruz (20.0% each), Jalisco (15.2%), Michoacán (6.6%). Phylogenetic analysis supported morphological identification confirmed genetic identity marginale. This research first report on molecular detection Mexico. Results suggest that this 3-host tick species might be potential vector. Mexico’s second most economically significant feeding after Rhipicephalus microplus. information about expands our understanding bovine epidemiology Further needed to assess role vector

Language: Английский

Citations

0
Role of Tick Commensal Bacteria in the Propagation of Emerging Infectious Diseases: Data Gaps and One Health Implications DOI Creative Commons
Uday Turaga, Steven M. Presley

Zoonotic Diseases, Journal Year: 2024, Volume and Issue: 4(4), P. 283 - 292

Published: Nov. 7, 2024

Ticks are obligate hematophagous ectoparasites notorious for their role as vectors of pathogens that affect humans and animals, particularly relative to the propagation emerging infectious diseases (EIDs). Two important factors facilitating ticks in EIDs potential development resistance acaricides expansion nonindigenous tick species into new geographic regions. The acquisition acaricide enables populations be less susceptible vector control programs. Expansion distribution increases likelihood access host well pathogens. Understanding microbiome continues evolve, providing critical insights biology. largely comprises endosymbionts, pathogenic organisms, commensal bacteria. Endosymbionts highly preserved vertically transmitted from mother offspring, survival is recognized. Similarly, established. However, bacteria acquired environment while ingesting a blood meal. Because many spend most lifetime off hosts, it can assumed richness diversity variable dependent on ecosystem which exists. This mini-review identifies some data gaps relevant influence vectorial capacity ticks. As move habitats, locally playing adaptation habitat? Apart conventionally understood mechanisms ticks, influencing at population level?

Language: Английский

Citations

0