Interplay between gut symbionts and behavioral variation in social insects DOI Creative Commons
Joanito Liberti,

Philipp Engel,

Amélie Cabirol

et al.

Current Opinion in Insect Science, Journal Year: 2024, Volume and Issue: 65, P. 101233 - 101233

Published: July 15, 2024

Social insects exhibit a high degree of intraspecific behavioral variation. Moreover, they often harbor specialized microbial communities in their gut. Recent studies suggest that these two characteristics social are interlinked: insect phenotypes affect gut microbiota composition, partly through exposure to different environments and diet, return, the has been shown influence behavior. Here, we discuss bidirectional relationship existing between variation composition insects.

Language: Английский

Changes in RNA Splicing: A New Paradigm of Transcriptional Responses to Probiotic Action in the Mammalian Brain DOI Creative Commons
Xiaojie Yue, Lei Zhu, Zhigang Zhang

et al.

Microorganisms, Journal Year: 2025, Volume and Issue: 13(1), P. 165 - 165

Published: Jan. 14, 2025

Elucidating the gene regulatory mechanisms underlying gut–brain axis is critical for uncovering novel interaction pathways and developing therapeutic strategies gut bacteria-associated neurological disorders. Most studies have primarily investigated how bacteria modulate host epigenetics expression; their impact on alternative splicing, particularly in brain, remains largely unexplored. Here, we effects of gut-associated probiotic Lacidofil® splicing across 10 regions rat brain using published RNA-sequencing data. The altogether altered 2941 differential events, predominantly, skipped exon (SE) mutually exclusive (MXE) events. Protein–protein interactions a KEGG analysis differentially spliced genes (DSGs) revealed consistent enrichment spliceosome vesicle transport complexes, as well related to neurodegenerative diseases, synaptic function plasticity, substance addiction regions. Using PsyGeNET platform, found that DSGs from locus coeruleus (LConly), medial preoptic area (mPOA), ventral dentate gyrus (venDG) were enriched depression-associated or schizophrenia-associated genes. Notably, highlight App gene, where precisely regulated two exons causally involved amyloid β protein-based diseases. Although factors exhibited both plasticity expression response Lacidofil®, overlap between expressed (DEGs) most was rather low. Our study provides mechanistic insight into probiotics might influence through modulation RNA splicing.

Language: Английский

Citations

0
Exploring the Mechanism of Treating IBS from the “Gallbladder” Based on Regulating Gut Microbiota DOI

霞 杨

Advances in Clinical Medicine, Journal Year: 2025, Volume and Issue: 15(01), P. 441 - 448

Published: Jan. 1, 2025

Language: Английский

Citations

0
The host phylogeny and climate determine the gut bacteria of global insects DOI
Shiqing Nie, Yong‐Jun Liu, Yuan Ge

et al.

The Science of The Total Environment, Journal Year: 2025, Volume and Issue: 966, P. 178812 - 178812

Published: Feb. 1, 2025

Language: Английский

Citations

0
Early life imidacloprid and copper exposure affects the gut microbiome, metabolism, and learning ability of honey bees (Apis mellifera). DOI

Xi-Jie Li,

Qihe Tang,

Mengshang Hou

et al.

Environmental Research, Journal Year: 2025, Volume and Issue: unknown, P. 121134 - 121134

Published: Feb. 1, 2025

Language: Английский

Citations

0
The Impact of Microbiota on Neurological Disorders: Mechanisms and Therapeutic Implications DOI Open Access
Giuseppe Merra,

Giada La Placa,

Marcello Covino

et al.

OBM Neurobiology, Journal Year: 2025, Volume and Issue: 09(01), P. 1 - 12

Published: Feb. 28, 2025

Interactions in the gut-brain crosstalk have led to development of an entirely new concept: "microbiota-gut-brain axis". Microbiota has gained considerable attention relation disorders a more neurological nature, such as neurodevelopmental and neuropsychiatric illnesses like autism spectrum disorder, anxiety, mood disorders. This review aims summarize recent trends insights into role consequences gut microbiota brain health pediatric Dysbiosis may be associated with increased risk diseases that lead different disruptions conditions, including mental issues. During dysbiosis, neuropsychological stress hormones usually affect oxytocin GABA neurons are significantly reduced. Current studies report major depression, cognitive dysfunction closely dysbiosis. In last few years, handful clinical emerged, illustrating potential for bidirectional relationship interactions humans. Perhaps some most crucial investigations demonstrating overlapping relationships human axis come from trials focusing on modulating noting significant correlates. A field is emerging gene-editing technology could represent tool improve microbial characteristics. approach particularly relevant neurodegenerative brain-gut linked loss species and/or high pathobiont load.

Language: Английский

Citations

0
The gut microbiome differs between hygiene-performing and non-hygiene-performing worker honey bees DOI Creative Commons
Yosef Hamba Tola, Kaira Wagoner, Mona-Lisa Strand

et al.

Insectes Sociaux, Journal Year: 2025, Volume and Issue: unknown

Published: March 6, 2025

Language: Английский

Citations

0
Standard methods and good practices in Apis honey bee omics research DOI
Maéva Angélique Techer, Priyadarshini Chakrabarti, Lílian Caesar

et al.

Journal of Apicultural Research, Journal Year: 2025, Volume and Issue: 64(2), P. 307 - 402

Published: March 15, 2025

Language: Английский

Citations

0
Influence of gut microbiota on behaviors of a honey bee DOI Open Access
Shota Suenami

Hikaku seiri seikagaku(Comparative Physiology and Biochemistry), Journal Year: 2025, Volume and Issue: 42(1), P. 37 - 45

Published: April 9, 2025

Language: Английский

Citations

0
Environment or genetic isolation? An atypical intestinal microbiota in the Maltese honey bee Apis mellifera spp. ruttneri DOI Creative Commons

Francesca Gaggìa,

Rasmus Riemer Jakobsen, Daniele Alberoni

et al.

Frontiers in Microbiology, Journal Year: 2023, Volume and Issue: 14

Published: Feb. 23, 2023

Apis mellifera evolved mainly in African, Asian, and European continents over thousands of years, leading to the selection a considerable number honey bees subspecies that have adapted various environments such as hot semi-desert zones cold temperate zones. With evolution bee subspecies, it is possible environmental conditions, food sources, microbial communities typical colonized areas shaped gut microbiota.In this study microbiota two distinct lineages (mitochondrial haplotypes) ruttneri (lineage A) ligustica carnica (both lineage C) were compared. Honey guts collected dry period respective breeding (the island Malta regions Emilia-Romagna South Tyrol Italy). Microbial DNA from was extracted amplified for V3-V4 16S rRNA gene bacteria ITS2 fungi.The analyses carried out show Maltese A distinctive when compared Italian C bees, with most abundant genera being Bartonellaceae Lactobacillaceae, respectively. Lactobacillaceae Lineage consist Apilactobacillus instead Lactobacillus Bombilactobacillus C. also harbors higher proportions Arsenophonus, Bombella, Commensalibacter, Pseudomonas C.The environment seems be main driver acquisition these marked differences microbiota. However, influence other factors host genetics, seasonality or geography may still play significant role microbiome shaping, synergy aspects.

Language: Английский

Citations

9
The buzz within: the role of the gut microbiome in honeybee social behavior DOI
Justine B. Nguyen, C. W. Marshall, Chelsea N. Cook

et al.

Journal of Experimental Biology, Journal Year: 2024, Volume and Issue: 227(3)

Published: Feb. 1, 2024

ABSTRACT Gut symbionts influence the physiology and behavior of their host, but extent to which these effects scale social behaviors is an emerging area research. The use western honeybee (Apis mellifera) as a model enables researchers investigate gut microbiome at several levels organization. Insight into microbial societal level critical for our understanding how involved are in host biology. In this Commentary, we discuss recent findings research synthesize with knowledge other organisms hypothesize host–microbe interactions individual could shape dynamics evolution.

Language: Английский

Citations

3