Journal of Gastrointestinal Oncology, Journal Year: 2024, Volume and Issue: 15(2), P. 800 - 802
Published: April 1, 2024
Language: Английский
Cancer Control, Journal Year: 2024, Volume and Issue: 31
Published: Jan. 1, 2024
In recent years, the relationship between microbes and tumors has led to a new wave of scholarly pursuits. Due growing awareness importance microbiota, including those within tumors, for cancer onset, progression, metastasis, treatment, researchers have come understand that microbiota tumor microenvironment together form dynamic complex ecosystem. Liquid biopsy technology, non-invasive easily repeatable method sample collection, combined with emerging multi-omics techniques, allows more comprehensive in-depth exploration microbial signals characteristics in bodily fluids. Microbial biomarkers hold immense potential early diagnosis, treatment stratification, prognosis prediction cancer. this review, we describe significant liquid clinical applications cancer, predicting responses, prognosis. Moreover, discuss current limitations solutions related biomarkers. This review aims provide an overview future directions practice.
Language: Английский
Citations
1
Microbial Pathogenesis, Journal Year: 2024, Volume and Issue: 197, P. 107091 - 107091
Published: Oct. 30, 2024
The discoveries of the oncomicrobiome (intratumoral microbiome) and oncomicrobiota microbiota) represent significant advances in tumor research have rapidly become key interest to field. Within tumors, microorganisms such as bacteria, fungi, viruses, archaea form are primarily found within cells, immunocytes, intercellular matrix. exhibits marked heterogeneity is associated with initiation, progression, metastasis, treatment response. Interactions between immune system can modulate host antitumor immunity, influencing efficacy immunotherapies. Oncomicrobiome also faces numerous challenges, including overcoming methodological issues low target abundance, susceptibility contamination, biases sample handling analysis methods across different studies. Furthermore, studies may be confounded by baseline differences microbiomes among populations driven both environmental genetic factors. Most date revealed associations but very few established mechanistic links two. This review introduces relevant concepts, detection methods, sources, characteristics oncomicrobiome. We then describe composition common tumors its role shaping microenvironment. discuss current problems challenges overcome this progressing
Language: Английский
Citations
1
Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15
Published: Aug. 7, 2024
Previous research has established associations between alterations in gut microbiota composition and various gynecologic tumors. However, establishing a causal relationship these tumors remains necessary. This study employs two-sample Mendelian randomization (MR) approach to investigate causality, aiming identify pathogenic bacterial communities potentially involved tumor development.
Language: Английский
Citations
0
Critical Reviews in Oncology/Hematology, Journal Year: 2024, Volume and Issue: unknown, P. 104545 - 104545
Published: Oct. 1, 2024
Language: Английский
Citations
0
Journal of Gastrointestinal Oncology, Journal Year: 2024, Volume and Issue: 15(2), P. 800 - 802
Published: April 1, 2024
Language: Английский
Citations
0