Investigating the Application of Pomegranate-Loaded Chitosan Nanoparticles as Contrast Agents for Enhancing Breast Cancer Detection via Diffuse Reflectance Spectroscopy
Chemosensors,
Journal Year:
2025,
Volume and Issue:
13(2), P. 73 - 73
Published: Feb. 17, 2025
The
present
cancer
diagnostic
techniques
and
contrast
agents
suffer
drawbacks,
adverse
effects,
poor
compatibility
with
patients
due
to
health
variations.
To
improve
the
detection
of
breast
cancer,
this
work
examined
contrasted
prospective
applications
pomegranates,
chitosan
nanoparticles
(Cs
NPs),
pomegranate-loaded
(PCs
NPs)
as
for
based
on
diffuse
reflectance
properties
at
following
laser
frequencies:
red
(670
nm)
near-infrared
(700
808
spectrum.
Herein,
a
platform
is
proposed,
offering
promising
pathway
detection.
PCs
NPs
two
different
pomegranate
contents
(2
5
g/L)
were
synthesized
using
sol–gel
method.
cytotoxicity
developed
nanomaterials
human
normal
(Vero)
(MCF7)
cell
lines
evaluated
in
presence
irradiation
670
nm,
fluorescent
effect
was
observed.
chemical
structures
extract
analyzed
FTIR,
they
then
further
analytically
characterized
dynamic
light
scattering,
zeta
potential,
field-emission
scanning
electron
microscopy.
Results
confirmed
structural
stability
nanomaterials.
Cytotoxicity
measurements
revealed
that
achieved
selective
cytotoxic
toward
tumor
cells.
also
showed
significant
wavelength-dependent
changes
characteristics
between
malignant
NPs,
content
g/L,
enhanced
cells
compared
more
than
three
folds.
These
findings
indicate
potential
distinguish
healthy
reflection
measurements.
Language: Английский
Advancing Biomedical Analysis: Harnessing Laser-Induced Graphene for Next-Gen of Low-Cost Sensor Technology
Journal of Pharmaceutical and Biomedical Analysis Open,
Journal Year:
2025,
Volume and Issue:
unknown, P. 100077 - 100077
Published: April 1, 2025
Language: Английский
Cytotoxicity and photothermal properties of graphene oxide conjugate with folic acid and a cytostatic agent of styryl thiazolopyrimidinium class
Fullerenes Nanotubes and Carbon Nanostructures,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 8
Published: Nov. 4, 2024
In
recent
years,
the
field
of
nanomedicine
has
garnered
significant
attention,
particularly
in
development
advanced
drug
delivery
systems.
Among
promising
materials,
highly
oxidized
graphene
oxide
(GO)
emerged
as
key
components
due
to
unique
physicochemical
properties
and
biocompatibility.
These
materials
offer
novel
avenues
for
targeted
delivery,
enhancing
therapeutic
efficacy
while
minimizing
side
effects.
This
article
explores
innovative
design
nanoparticle-based
systems
utilizing
with
folic
acid
combination
thiazolopyrimidinium
salt,
highlighting
their
potential
applications
medicine.
Language: Английский