Trends and projections of the burden of visual impairment in Asia: findings from the Global Burden of Disease Study 2021 DOI Creative Commons
Shengsong Xu, Jianqi Chen, Xiao Wang

et al.

Asia-Pacific Journal of Ophthalmology, Journal Year: 2025, Volume and Issue: unknown, P. 100196 - 100196

Published: April 1, 2025

This study aims to examine the trends in burden of visual impairment across Asia from 1990 2021 and project through 2040. population-based used data latest Global Burden Disease study. Prevalence years lived with disability (YLDs) were main outcomes. The analyzed by calculating average annual percentage change (AAPC) using joinpoint regression analysis. projection was performed Bayesian age-period-cohort modeling. prevalence increased 2021, AAPCs 0.77 (95% confidence interval [CI], 0.44 1.11), while YLD rates decreased -0.21 CI, -0.38 -0.03). Near vision loss contributor Asia. Notably, working-age population (20 54 years) significantly (AAPC = 2.11 [95% 1.70 2.53]), which accord YLDs 1.07 0.83 1.32]), whereas for children adolescents (<20 elderly (≥55 it has decreased. According projection, predicted increase all Asian sub-regions, especially East South been substantially increasing 2021. trend is anticipated persist soon, Asia, underlining urgent need concentrated attention robust policy support these regions.

Language: Английский

MiniMed 780G system performance in older users with type 1 diabetes: Real‐world evidence and the case for stricter glycaemic targets DOI Creative Commons

Vittorino Smaniotto,

Simon Heller, David N. O’Neal

et al.

Diabetes Obesity and Metabolism, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 4, 2025

Abstract Aims Large‐scale studies on the effectiveness of automated insulin delivery (AID) systems in older people with type 1 diabetes are still limited. A multinational, retrospective, real‐world study was conducted to examine performance MiniMed™ 780G advanced hybrid closed‐loop system users aged ≥56 years compared those 16–55 years. Materials and Methods Data from 35 366 7415 were included. The main outcome time range 70–180 mg/dL (TIR); other continuous glucose monitoring (CGM) metrics also assessed. Results Across all users, mean TIR 77.1% for 73.1% (Δ4.0, 95% confidence interval [CI]: 3.8–4.2, p <0.0001). In employing optimal settings (i.e., Glucose Target: 100 mg/dL; active time: 2 h), 81.9% 79.7% younger (Δ2.2, CI: 1.5–2.9, below <70 (TBR 70 ) 1.5% 2.1% users. TBR remained consistent over 12 months. Conclusions This analysis demonstrated that can achieve a >70% without increasing hypoglycaemia risk. Users showed best outcomes. performed as well or better than These findings support case more stringent targets be achieved safely.

Language: Английский

Citations

0
Global burden of central nervous system tumors and cancers in older adults: the global burden of disease study 2021 DOI
Peng Liu, Lunxin Liu, Xiaoyin Liu

et al.

Journal of Neurology, Journal Year: 2025, Volume and Issue: 272(3)

Published: Feb. 11, 2025

Language: Английский

Citations

0
Global burden and risk factors of male cancers from 1990 to 2021, with forecasts to 2040 DOI Creative Commons

Youao Zhang,

P. Wang, Zixuan Jia

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Feb. 11, 2025

Male cancers, which refers to cancers that occur exclusively in males, is a prevalent type of cancer worldwide, primarily including prostate (PCa) and testicular (TCa). These are significant contributors the global disease burden. We aim study specific patterns trends male from 1990 2021 inform health policy, allocation medical resources, optimization patient management plans. analyzed Global Burden Disease (GBD) on data for 21 regions 204 countries understand better burden using prevalence, incidence, mortality, disability-adjusted life years (DALYs). tested correlations with Socio-demographic Index (SDI) Spearman's analysis. Decomposition analysis was utilized dissect reasons behind changes epidemiological indicators disease, autoregressive integrated moving average (ARIMA) modeling forecasted future trends. In 2021, age-standardized rates (ASR) per 100,000 people PCa terms deaths, DALYs were 260.05, 34.05, 12.63, 217.83, respectively, while TCa 16.59, 2.24, 0.29, 13.83, respectively. Compared 1990, ratios changed by 0.19, 0.04, -0.23, − 0.21, they 0.66, 0.5, -0.14, 0.08, Age revealed heavier after age 70 25–34 group. High SDI, ASR prevalence incidence higher, Low deaths higher. Aging main reason increase PCa, change TCa, population growth death 2021. Smoking high calcium diets risk factors PCa. For forecast 2040, projected be 266.23, 35.21, 9.11, 176.16, respectively; 20.63, 2.7, 0.26, 12.73, From projections generally show an upward trend, exhibit downward trend. Additionally, higher individuals over middle-aged group 25 34 highlights urgent need healthcare professionals policymakers propose innovative prevention strategies based existing its new changes, alleviate cancers.

Language: Английский

Citations

0
Global Epidemiology of Early-Onset Aortic Aneurysm: Temporal Trends, Risk Factors, and Future Burden Projections DOI Creative Commons
Heng Wang, Yaling Li, Keyi Fan

et al.

Journal of Epidemiology and Global Health, Journal Year: 2025, Volume and Issue: 15(1)

Published: Feb. 13, 2025

Language: Английский

Citations

0
The Burden of adolescent depression and the impact of COVID-19 across 204 countries and regions from 1990 to 2021: results from the 2021 global burden of disease study DOI Creative Commons

Feiyun Zhu,

Ying Yang,

Tongle Yin

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Feb. 15, 2025

Language: Английский

Citations

0
Temporal trends in the planetary health diet index and its association with cardiovascular, kidney, and metabolic diseases: A comprehensive analysis from global and individual perspectives DOI Creative Commons
Haoxian Tang, Xuan Zhang, Nan Luo

et al.

The journal of nutrition health & aging, Journal Year: 2025, Volume and Issue: 29(5), P. 100520 - 100520

Published: Feb. 21, 2025

Diet plays a critical role in human health and environmental sustainability, particularly cardiovascular, kidney, metabolic (CKM) diseases. However, the variations Planetary Health Index (PHDI) across populations, regions, over time, as well its association with CKM disease burdens, remain insufficiently explored. We assessed PHDI scores using data from 185 countries (1990-2018) Global Dietary Database, examining demographic characteristics temporal trends. The Burden of Disease Study was used to evaluate associations between including incidence, prevalence, mortality, disability-adjusted life years. syndrome defined by American Heart Association. Individual-level National Nutrition Examination Survey (NHANES) were also assess impact on risks mortality. From 1990 2018, while overall remained relatively stable sexes, composition shifted different age groups. In mean score 42.80 (95% uncertainty interval [UI] 42.49-46.50) for males 44.65 UI 44.53-47.82) females. Higher observed among females, older adults, urban residents, individuals higher education, those South Asia. Globally, consumption red/processed meat, saturated oils/trans fats, added sugars substantially exceeded EAT-Lancet Commission's reference values. generally associated lower although these varied subtype. individual-level analysis, 45,460 NHANES participants (weighted age: 47.21 years, 51.4% female), each 10-point increase linked 13.7% reduction stage 3/4 risk, an 11.1% 4 incidences mortality rates cardiovascular diseases, chronic kidney disease. significant changes occurred components PHDI, notable demographics region. may reduce warranting further investigation into specific subtypes.

Language: Английский

Citations

0
Challenges, current innovations, and opportunities for managing type 2 diabetes in frail older adults: a position paper of the European Geriatric Medicine Society (EuGMS)—Special Interest Group in Diabetes DOI Creative Commons
Virginia Boccardi,

Gülistan Bahat,

Cafer Balcı

et al.

European Geriatric Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 27, 2025

This position paper aims to address the challenges of managing type 2 diabetes mellitus (T2DM) in frail older adults, a diverse and growing demographic with significant variability health status. The primary research questions are: How can frailty assessment be effectively integrated into care? What strategies optimize glycaemic control outcomes for adults? innovative tools technologies, including artificial intelligence (AI), improve management this population? uses 5 I's framework (Identification, Innovation, Individualization, Integration, Intelligence) integrate care, proposing such as tools, novel therapies, digital AI systems. It also examines metabolic heterogeneity, highlighting anorexic-malnourished sarcopenic-obese phenotypes. proposed highlights importance tailoring targets levels, prioritizing quality life, minimizing treatment burden. Strategies leveraging are emphasized their potential enhance personalized care. distinct needs two phenotypes outlined, specific recommendations each group. calls holistic, patient-centered approach care ensuring equity access innovations life. need fill evidence gaps, refine healthcare integration better vulnerable

Language: Английский

Citations

0
Global Burden of Thyroid Cancer in Children and Adolescents, 1990–2021: Trends, Disparities, and Future Projections DOI Open Access
Tianyu Li, Zhen Cao, Lin Chen

et al.

Cancers, Journal Year: 2025, Volume and Issue: 17(5), P. 892 - 892

Published: March 5, 2025

Thyroid cancer is a rising concern in children and adolescents, with unique biological behaviors compared to adults. This study aimed explore the epidemiological trends, pathological features, regional disparities of thyroid this population using data from Global Burden Disease (GBD) 2021. Data on incidence mortality 1990 2021 were extracted for individuals under 20 years old. The estimated annual percentage change (EAPC) was calculated evaluate temporal trends. Sociodemographic Index (SDI) applied assess variations. Future trends projected Bayesian age-period-cohort model. From 2021, global adolescents increased significantly, an EAPC 1.17%. Low-SDI regions exhibited highest rise (EAPC: 2.19%), while high-SDI experienced slight decline -0.69%). Mortality decreased globally -0.27%), notable reductions high- middle-SDI but stable or increasing rates low-SDI regions. Females consistently higher across all SDI levels, males showed rates. projections suggest steady through 2050. persistent highlight need targeted public health interventions. Regions low socioeconomic development require prioritized strategies address growing burden. These findings provide crucial insights early diagnosis, treatment optimization, policy formulation.

Language: Английский

Citations

0
Global, regional, and national burden of kidney cancer and attributable risk factors in adults aged 65 years and older from 1990 to 2021 and projections to 2040 DOI Creative Commons

Nan Zhou,

Heming Bai, Ziyan Zhang

et al.

BMC Cancer, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 15, 2025

Identifying the past and future burden of kidney cancer (KC) its temporal trends among older adults (≥ 65 years) at global, regional, national levels is critical for effective prevention strategies. The age-standardized incidence, prevalence, mortality, disability-adjusted life years (DALYs) were calculated using data from Global Burden Disease (GBD) study 1990 to 2021. These indicators stratified by sex, age, socio-demographic index (SDI). correlation between these SDI was assessed. Temporal quantified annual average percentage change (AAPC), 2022 2040 predicted Bayesian age-period-cohort (BAPC) model. global incidence rate (ASIR) KC increased 21.73 per 100,000 people in 26.74 2021, with an AAPC 0.67%. Age-standardized DALYs (ASDR) remained stable, while significant increases observed prevalence (AAPC = 1.24%, 95%CI: 1.14–1.34%) mortality 0.13%, 0.05–0.22%). From males consistently exhibited a higher disease than females, additionally, ASIR significantly all age subgroups. Regions also showed greater burden, Oceania had lowest almost countries territories. Czechia highest (92.25 people) ASDR (819.88 people). Smoking high body mass (BMI) risk factors population, their effects greatest region. Furthermore, expected continue decline through 2040. notable regional variations. However, it projected management smoking BMI remain major challenges KC, necessitating targeted clinical guidelines, particularly focusing on adults.

Language: Английский

Citations

0
The association between air pollution and three types of diabetes: An umbrella review of systematic reviews and meta-analyses DOI

Weicong Jiang,

Huili Zhou,

Guangbiao Xu

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 294, P. 118080 - 118080

Published: March 21, 2025

Language: Английский

Citations

0