PLoS ONE,
Journal Year:
2021,
Volume and Issue:
16(5), P. e0251123 - e0251123
Published: May 5, 2021
Background
There
is
a
lack
of
population
level
data
on
risk
factors,
incidence
and
impact
SARS-CoV-2
infection
in
pregnant
women
their
babies.
The
primary
aim
this
study
was
to
describe
the
incidence,
characteristics
outcomes
hospitalized
with
symptomatic
asymptomatic
UK
compared
without
SARS-CoV-2.
Methods
findings
We
conducted
national,
prospective
cohort
all
confirmed
from
01/03/2020
31/08/2020
using
Obstetric
Surveillance
System.
Incidence
rates
were
estimated
national
maternity
data.
Overall,
1148
had
pregnancy,
63%
which
symptomatic.
hospitalization
2.0
per
1000
maternities
(95%
CI
1.9–2.2)
for
1.2
1.1–1.4).
Compared
SARS-CoV-2,
more
likely
be
overweight
or
obese
(adjusted
OR
1.86,
1.39–2.48)
aOR
2.07
(1.53–2.29)),
Black,
Asian
Other
minority
ethnic
group
(aOR
6.24,
(3.93–9.90),
4.36,
(3.19–5.95)
12.95,
(4.93–34.01)),
have
relevant
medical
comorbidity
1.83
(1.32–2.54)).
Hospitalized
admitted
intensive
care
57.67,
(7.80–426.70))
but
absolute
poor
low.
Cesarean
births
neonatal
unit
admission
increased
regardless
symptom
status
(symptomatic
2.60,
(1.97–3.42)
3.08,
(1.99–4.77);
2.02,
(1.52–2.70)
1.84,
(1.12–3.03)).
risks
stillbirth
death
not
significantly
increased,
status.
Conclusions
identified
factors
that
increase
pregnancy.
Clinicians
can
reassured
majority
do
experience
severe
complications
Circulation,
Journal Year:
2022,
Volume and Issue:
145(8)
Published: Jan. 26, 2022
The
American
Heart
Association,
in
conjunction
with
the
National
Institutes
of
Health,
annually
reports
most
up-to-date
statistics
related
to
heart
disease,
stroke,
and
cardiovascular
risk
factors,
including
core
health
behaviors
(smoking,
physical
activity,
diet,
weight)
factors
(cholesterol,
blood
pressure,
glucose
control)
that
contribute
health.
Statistical
Update
presents
latest
data
on
a
range
major
clinical
circulatory
disease
conditions
(including
congenital
rhythm
disorders,
subclinical
atherosclerosis,
coronary
failure,
valvular
venous
peripheral
artery
disease)
associated
outcomes
quality
care,
procedures,
economic
costs).
Circulation,
Journal Year:
2023,
Volume and Issue:
147(8)
Published: Jan. 25, 2023
Background:
The
American
Heart
Association,
in
conjunction
with
the
National
Institutes
of
Health,
annually
reports
most
up-to-date
statistics
related
to
heart
disease,
stroke,
and
cardiovascular
risk
factors,
including
core
health
behaviors
(smoking,
physical
activity,
diet,
weight)
factors
(cholesterol,
blood
pressure,
glucose
control)
that
contribute
health.
Statistical
Update
presents
latest
data
on
a
range
major
clinical
circulatory
disease
conditions
(including
congenital
rhythm
disorders,
subclinical
atherosclerosis,
coronary
failure,
valvular
venous
peripheral
artery
disease)
associated
outcomes
quality
care,
procedures,
economic
costs).
Methods:
through
its
Epidemiology
Prevention
Statistics
Committee,
continuously
monitors
evaluates
sources
stroke
United
States
provide
current
information
available
annual
review
published
literature
year
before
writing.
2023
is
product
full
year’s
worth
effort
2022
by
dedicated
volunteer
clinicians
scientists,
committed
government
professionals,
Association
staff
members.
strives
further
understand
help
heal
problems
inflicted
structural
racism,
public
crisis
can
significantly
damage
mental
perpetuate
disparities
access
education,
income,
housing,
several
other
vital
healthy
lives.
This
edition
includes
additional
COVID-19
(coronavirus
2019)
publications,
as
well
monitoring
benefits
population,
an
enhanced
focus
equity
across
key
domains.
Results:
Each
chapters
focuses
different
topic
statistics.
Conclusions:
represents
critical
resource
for
lay
public,
policymakers,
media
clinicians,
care
administrators,
researchers,
advocates,
others
seeking
best
these
conditions.
BMJ,
Journal Year:
2020,
Volume and Issue:
unknown, P. m3320 - m3320
Published: Sept. 1, 2020
Abstract
Objective
To
determine
the
clinical
manifestations,
risk
factors,
and
maternal
perinatal
outcomes
in
pregnant
recently
women
with
suspected
or
confirmed
coronavirus
disease
2019
(covid-19).
Design
Living
systematic
review
meta-analysis.
Data
sources
Medline,
Embase,
Cochrane
database,
WHO
COVID-19
China
National
Knowledge
Infrastructure
(CNKI),
Wanfang
databases
from
1
December
to
27
April
2021,
along
preprint
servers,
social
media,
reference
lists.
Study
selection
Cohort
studies
reporting
rates,
manifestations
(symptoms,
laboratory
radiological
findings),
covid-19.
extraction
At
least
two
researchers
independently
extracted
data
assessed
study
quality.
Random
effects
meta-analysis
was
performed,
estimates
pooled
as
odds
ratios
difference
proportions
95%
confidence
intervals.
All
analyses
are
updated
regularly.
Results
435
were
included.
Overall,
9%
(95%
interval
7%
10%;
149
studies,
926
232
women)
of
attending
admitted
hospital
for
any
reason
diagnosed
having
The
most
common
covid-19
pregnancy
fever
cough
(both
36%).
Compared
non-pregnant
reproductive
age,
less
likely
report
symptoms
fever,
dyspnoea,
cough,
myalgia.
admission
an
intensive
care
unit
(odds
ratio
2.61,
1.84
3.71;
I
2
=85.6%),
invasive
ventilation
(2.41,
2.13
2.71;
=0%)
higher
than
age.
970
(0.2%,
123
179
981
died
cause.
In
covid-19,
non-white
ethnicity,
increased
high
body
mass
index,
pre-existing
comorbidity
including
chronic
hypertension
diabetes,
specific
complications
such
gestational
diabetes
pre-eclampsia,
associated
serious
(severe
unit,
ventilation,
death).
without
those
had
death
6.09,
1.82
20.38;
=76.6%),
(5.41,
3.59
8.14;
=57.0%),
caesarean
section
(1.17,
1.01
1.36;
=80.3%),
preterm
birth
(1.57,
1.36
1.81;
=49.3%).
stillbirth
(1.81,
1.38
2.37,
=0%),
neonatal
(2.18,
1.46
3.26,
=85.4%)
babies
born
versus
Conclusion
Pregnant
hospitals
manifest
myalgia,
but
more
be
needing
Pre-existing
comorbidities,
hypertension,
index
factors
severe
pregnancy.
deliver
have
being
unit.
Their
Systematic
registration
PROSPERO
CRD42020178076.
Readers’
note
This
article
is
a
living
that
will
reflect
emerging
evidence.
Updates
may
occur
up
years
date
original
publication.
version
update
published
on
September
2020
(
BMJ
2020;370:m3320),
previous
updates
can
found
supplements
https://www.bmj.com/content/370/bmj.m3320/related#datasupp
).
When
citing
this
paper
please
consider
adding
number
access
clarity.
MMWR Morbidity and Mortality Weekly Report,
Journal Year:
2020,
Volume and Issue:
69(44), P. 1641 - 1647
Published: Nov. 2, 2020
Studies
suggest
that
pregnant
women
might
be
at
increased
risk
for
severe
illness
associated
with
coronavirus
disease
2019
(COVID-19)
(1,2).
This
report
provides
updated
information
about
symptomatic
of
reproductive
age
(15-44
years)
laboratory-confirmed
infection
SARS-CoV-2,
the
virus
causes
COVID-19.
During
January
22-October
3,
CDC
received
reports
through
national
COVID-19
case
surveillance
or
National
Notifiable
Diseases
Surveillance
System
(NNDSS)
1,300,938
aged
15-44
years
laboratory
results
indicative
acute
SARS-CoV-2.
Data
on
pregnancy
status
were
available
461,825
(35.5%)
infection,
409,462
(88.7%)
whom
symptomatic.
Among
women,
23,434
(5.7%)
reported
to
pregnant.
After
adjusting
age,
race/ethnicity,
and
underlying
medical
conditions,
significantly
more
likely
than
nonpregnant
admitted
an
intensive
care
unit
(ICU)
(10.5
versus
3.9
per
1,000
cases;
adjusted
ratio
[aRR]
=
3.0;
95%
confidence
interval
[CI]
2.6-3.4),
receive
invasive
ventilation
(2.9
1.1
aRR
2.9;
CI
2.2-3.8),
extracorporeal
membrane
oxygenation
(ECMO)
(0.7
0.3
2.4;
1.5-4.0),
die
(1.5
1.2
1.7;
1.2-2.4).
Stratifying
these
analyses
by
race/ethnicity
highlighted
disparities
in
subgroup.
Although
absolute
risks
outcomes
low,
COVID-19-associated
illness.
To
reduce
death
from
COVID-19,
should
counseled
importance
seeking
prompt
if
they
have
symptoms
measures
prevent
SARS-CoV-2
strongly
emphasized
their
families
during
all
encounters,
including
prenatal
visits.
Understanding
among
is
important
prevention
counseling
clinical
treatment.
Circulation,
Journal Year:
2024,
Volume and Issue:
149(8)
Published: Jan. 24, 2024
BACKGROUND:
The
American
Heart
Association
(AHA),
in
conjunction
with
the
National
Institutes
of
Health,
annually
reports
most
up-to-date
statistics
related
to
heart
disease,
stroke,
and
cardiovascular
risk
factors,
including
core
health
behaviors
(smoking,
physical
activity,
nutrition,
sleep,
obesity)
factors
(cholesterol,
blood
pressure,
glucose
control,
metabolic
syndrome)
that
contribute
health.
AHA
Disease
Stroke
Statistical
Update
presents
latest
data
on
a
range
major
clinical
circulatory
disease
conditions
(including
brain
health,
complications
pregnancy,
kidney
congenital
rhythm
disorders,
sudden
cardiac
arrest,
subclinical
atherosclerosis,
coronary
cardiomyopathy,
failure,
valvular
venous
thromboembolism,
peripheral
artery
disease)
associated
outcomes
quality
care,
procedures,
economic
costs).
METHODS:
AHA,
through
its
Epidemiology
Prevention
Statistics
Committee,
continuously
monitors
evaluates
sources
stroke
United
States
globally
provide
current
information
available
annual
review
published
literature
year
before
writing.
2024
is
product
full
year’s
worth
effort
2023
by
dedicated
volunteer
clinicians
scientists,
committed
government
professionals,
staff
members.
strives
further
understand
help
heal
problems
inflicted
structural
racism,
public
crisis
can
significantly
damage
mental
perpetuate
disparities
access
education,
income,
housing,
several
other
vital
healthy
lives.
This
edition
includes
additional
global
data,
as
well
monitoring
benefits
population,
an
enhanced
focus
equity
across
key
domains.
RESULTS:
Each
chapters
focuses
different
topic
statistics.
CONCLUSIONS:
represents
critical
resource
for
lay
public,
policymakers,
media
clinicians,
care
administrators,
researchers,
advocates,
others
seeking
best
these
conditions.
New England Journal of Medicine,
Journal Year:
2021,
Volume and Issue:
384(24), P. 2273 - 2282
Published: April 21, 2021
Many
pregnant
persons
in
the
United
States
are
receiving
messenger
RNA
(mRNA)
coronavirus
disease
2019
(Covid-19)
vaccines,
but
data
limited
on
their
safety
pregnancy.From
December
14,
2020,
to
February
28,
2021,
we
used
from
"v-safe
after
vaccination
health
checker"
surveillance
system,
v-safe
pregnancy
registry,
and
Vaccine
Adverse
Event
Reporting
System
(VAERS)
characterize
initial
of
mRNA
Covid-19
vaccines
persons.A
total
35,691
participants
16
54
years
age
identified
as
pregnant.
Injection-site
pain
was
reported
more
frequently
among
than
nonpregnant
women,
whereas
headache,
myalgia,
chills,
fever
were
less
frequently.
Among
3958
enrolled
827
had
a
completed
pregnancy,
which
115
(13.9%)
resulted
loss
712
(86.1%)
live
birth
(mostly
with
third
trimester).
neonatal
outcomes
included
preterm
(in
9.4%)
small
size
for
gestational
3.2%);
no
deaths
reported.
Although
not
directly
comparable,
calculated
proportions
adverse
vaccinated
against
who
similar
incidences
studies
involving
women
that
conducted
before
pandemic.
221
pregnancy-related
events
VAERS,
most
event
spontaneous
abortion
(46
cases).Preliminary
findings
did
show
obvious
signals
received
vaccines.
However,
longitudinal
follow-up,
including
follow-up
large
numbers
earlier
is
necessary
inform
maternal,
infant
outcomes.
Canadian Medical Association Journal,
Journal Year:
2021,
Volume and Issue:
193(16), P. E540 - E548
Published: March 19, 2021
The
impact
of
coronavirus
disease
2019
(COVID-19)
on
maternal
and
newborn
health
is
unclear.
We
aimed
to
evaluate
the
association
between
severe
acute
respiratory
syndrome
2
(SARS-CoV-2)
infection
during
pregnancy
adverse
outcomes.We
conducted
a
systematic
review
meta-analysis
observational
studies
with
comparison
data
SARS-CoV-2
severity
COVID-19
pregnancy.
searched
for
eligible
in
MEDLINE,
Embase,
ClinicalTrials.gov,
medRxiv
Cochrane
databases
up
Jan.
29,
2021,
using
Medical
Subject
Headings
terms
keywords
"severe
OR
COVID-19"
AND
"pregnancy."
evaluated
methodologic
quality
all
included
Newcastle-Ottawa
Scale.
Our
primary
outcomes
were
preeclampsia
preterm
birth.
Secondary
stillbirth,
gestational
diabetes
other
outcomes.
calculated
summary
odds
ratios
(ORs)
or
weighted
mean
differences
95%
confidence
intervals
(CI)
random-effects
meta-analysis.We
42
involving
438
548
people
who
pregnant.
Compared
no
pregnancy,
was
associated
(OR
1.33,
CI
1.03
1.73),
birth
1.82,
1.38
2.39)
stillbirth
2.11,
1.14
3.90).
mild
COVID-19,
strongly
4.16,
1.55
11.15),
4.29,
2.41
7.63),
1.99,
1.09
3.64)
low
weight
1.89,
3.12).COVID-19
may
be
increased
risks
preeclampsia,
Reproductive Health,
Journal Year:
2021,
Volume and Issue:
18(1)
Published: Jan. 18, 2021
Abstract
Introduction
The
Covid-19
pandemic
affects
maternal
health
both
directly
and
indirectly,
direct
indirect
effects
are
intertwined.
To
provide
a
comprehensive
overview
on
this
broad
topic
in
rapid
format
behooving
an
emergent
we
conducted
scoping
review.
Methods
A
review
was
to
compile
evidence
impacts
of
the
most
significant
outcomes
thus
far.
Working
papers
news
articles
were
considered
appropriate
along
with
peer-reviewed
publications
order
capture
rapidly
evolving
updates.
Literature
English
published
from
January
1st
September
11
2020
included
if
it
pertained
or
COVID-19
physical,
mental,
economic,
social
wellbeing
pregnant
people.
Narrative
descriptions
written
about
subject
areas
for
which
authors
found
evidence.
Results
search
yielded
396
publications,
95
included.
Pregnant
individuals
be
at
heightened
risk
more
severe
symptoms
than
people
who
not
pregnant.
Intrauterine,
vertical,
breastmilk
transmission
unlikely.
Labor,
delivery,
breastfeeding
guidelines
positive
patients
varied.
Severe
increases
mental
issues,
such
as
clinically
relevant
anxiety
depression,
reported.
Domestic
violence
appeared
spike.
Prenatal
care
visits
decreased,
healthcare
infrastructure
strained,
potentially
harmful
policies
implemented
little
Women
likely
lose
their
income
due
men,
working
mothers
struggled
increased
childcare
demands.
Conclusion
women
higher
infection
pregnant,
however
symptomatic
may
experience
adverse
compared
non-pregnant
seem
face
disproportionate
socio-economic
consequences.
High
low-
middle-income
countries
alike
faced
struggles.
Further
resources
should
directed
towards
quality
epidemiological
studies.
Plain
summary
reproductive
perinatal
through
itself
but
also
indirectly
consequence
changes
care,
policy,
economic
circumstances.
consequences
have
Intrauterine
transmission,
passage
virus
mother
baby
during
delivery
labor,
vary,
variability
could
create
uncertainty
unnecessary
harm.
high
low/middle
countries.
impact
is
marked.
frequency
problems,
epidemic
reported
many
This
reflects
increase
studies
demonstrating
true
change
lacking.
vulnerable
losing
We
make
several
recommendations:
studies,
services
diminished,
focus
needed.
Obstetrics and Gynecology,
Journal Year:
2021,
Volume and Issue:
137(4), P. 571 - 580
Published: Feb. 8, 2021
OBJECTIVE:
To
describe
coronavirus
disease
2019
(COVID-19)
severity
in
pregnant
patients
and
evaluate
the
association
between
perinatal
outcomes.
METHODS:
We
conducted
an
observational
cohort
study
of
all
with
a
singleton
gestation
positive
test
result
for
severe
acute
respiratory
syndrome
2
(SARS-CoV-2)
who
delivered
at
1
33
U.S.
hospitals
14
states
from
March
to
July
31,
2020.
Disease
was
classified
by
National
Institutes
Health
criteria.
Maternal,
fetal,
neonatal
outcomes
were
abstracted
centrally
trained
certified
research
staff.
evaluated
trends
maternal
characteristics
across
COVID-19
classes
associations
multivariable
modeling.
RESULTS:
A
total
1,219
included:
47%
asymptomatic,
27%
mild,
14%
moderate,
8%
severe,
4%
critical.
Overall,
53%
Hispanic;
there
no
trend
race–ethnicity
distribution
severity.
Those
more
illness
had
older
mean
age,
higher
median
body
mass
index,
pre-existing
medical
comorbidities.
Four
deaths
(0.3%)
attributed
COVID-19.
Frequency
death
or
SARS-CoV-2
did
not
differ
Adverse
frequent
among
illness,
including
6%
(95%
CI
2–11%)
incidence
venous
thromboembolism
those
severe–critical
compared
0.2%
mild–moderate
0%
asymptomatic
(
P
<.001
severity).
In
adjusted
analyses,
associated
increased
risk
cesarean
birth
(59.6%
vs
34.0%,
relative
[aRR]
1.57,
95%
1.30–1.90),
hypertensive
disorders
pregnancy
(40.4%
18.8%,
aRR
1.61,
1.18–2.20),
preterm
(41.8%
11.9%,
3.53,
2.42–5.14)
patients.
Mild–moderate
adverse
CONCLUSION:
Compared
infection
without
symptoms,
COVID-19,
but
complications.