SARS-CoV-2 infection and the risk of depressive symptoms: a retrospective longitudinal study from the population-based CONSTANCES cohort DOI Creative Commons
Baptiste Pignon, Emmanuel Wiernik, Brigitte Ranque

et al.

Psychological Medicine, Journal Year: 2024, Volume and Issue: 54(14), P. 3939 - 3948

Published: Oct. 1, 2024

Abstract Background Should COVID-19 have a direct impact on the risk of depression, it would suggest specific pathways for prevention and treatment. In this retrospective population-based study, we aimed to examine association prior SARS-CoV-2 infection with depressive symptoms, distinguishing self-reported v . biologically confirmed COVID-19. Methods 32 007 participants from SAPRIS survey nested in French CONSTANCES cohort were included. was measured as followed: ad hoc serologic testing, PCR or serology positive test results, Depressive symptoms Center Epidemiologic Studies-Depression Scale (CES-D). Outcomes (total CES-D score, its four dimensions, clinically significant symptoms) exposure (no COVID-19/self-reported unconfirmed COVID-19/biologically COVID-19). Results comparison without COVID-19, had higher scores ( β one interquartile range increase [95% CI]: 0.15 [0.08–0.22] 0.09 [0.05–0.13], respectively) somatic complaints dimension (0.15 [0.09–0.21] 0.10 [0.07–0.13]). Only those but depressed affect (0.08 [0.01–0.14]). Accounting testing only, score only associated combination negative results. Conclusions The between merely driven by depression did not follow gradient consistent hypothesis depression.

Language: Английский

Course of neuropsychological health in post-COVID patients differs 6 and 12 months after inpatient rehabilitation DOI Creative Commons
Katrin Müller,

Iris Poppele,

Marcel Ottiger

et al.

Frontiers in Psychiatry, Journal Year: 2025, Volume and Issue: 16

Published: April 25, 2025

Background Rehabilitation is an effective and feasible approach for post-COVID patients to improve mental health cognitive complaints. However, knowledge regarding the long-term impact of rehabilitation on neuropsychological these lacking. Objective This study aims investigate psychological health, fatigue, function 6 12 months after inpatient patients, who acquired COVID-19 in workplace. In addition, group differences outcome parameters according sex, age, acute COVID status, socioeconomic profession, pre-existing diseases will be detected. Methods longitudinal observational examined changes 127 with as occupational disease or work accident. Symptoms depression anxiety, fatigue severity, somatic symptom trauma-related symptoms, functioning were assessed at beginning well six rehabilitation. Group concerning existing prior also analyzed. Results The results showed that improvements direct severity could not maintained discharge. Contrary, patients’ stable during follow-up. Significant observed diseases. Conclusion highlights importance aftercare process implementation adequate individualized therapeutic interventions such support strengthen self-management skills. registered German Clinical Trials Register identifier DRKS00022928.

Language: Английский

Citations

0

Depressive symptoms and sex differences in the risk of post-COVID-19 persistent symptoms: a prospective population-based cohort study DOI
Joane Matta, Baptiste Pignon, Sofiane Kab

et al.

Nature Mental Health, Journal Year: 2024, Volume and Issue: 2(9), P. 1053 - 1061

Published: July 17, 2024

Language: Английский

Citations

3

A prospective non-randomized controlled trial testing the effectiveness of psychotherapeutic inpatient treatment of Post-COVID-19 syndrome - study protocol DOI Creative Commons
Katharina Koller,

Silke Kastel-Hoffmann,

Regina Herold

et al.

BMC Psychology, Journal Year: 2024, Volume and Issue: 12(1)

Published: Sept. 16, 2024

Abstract Introduction In addition to physical symptoms such as dyspnea, fatigue, post-exertional malaise, and pain, a subgroup of patients with Post-COVID-19 syndrome (Post-Acute Sequelae COVID-19, PASC) suffers from mental illnesses anxiety, depression, neurocognitive impairments. To date, there are no causal treatments available for PASC. While initial studies show that psychotherapy improves psychological symptoms, PASC-related psychosocial functioning, further research is needed evaluate the effectiveness psychotherapeutic treatment Methods analysis This study presents non-randomized controlled trial aimed at evaluating five-week multimodal inpatient psychosomatic program individuals experiencing PASC comorbid illness. A total 118 presented Post-COVID Center Universitätsklinikum Erlangen will be assigned intervention group receiving or control usual. The inclusion criteria diagnosis least one condition distress problems coping primary objective reduce ailments, including depression well deficits, address fatigue pain. core elements in individual settings, medical treatment, training, therapy, adapted individual’s capacity oriented towards concept pacing. After enrollment, participants undergo 6-month follow-up assess long-term results sustainability effects. Discussion examines illness comparison based on can contribute development evidence-based interventions complex needs Trial registration German Clinical Register (DRKS), retrospectively registered 15.02.2024 DRKSID DRKS00033562.

Language: Английский

Citations

0

SARS-CoV-2 infection and the risk of depressive symptoms: a retrospective longitudinal study from the population-based CONSTANCES cohort DOI Creative Commons
Baptiste Pignon, Emmanuel Wiernik, Brigitte Ranque

et al.

Psychological Medicine, Journal Year: 2024, Volume and Issue: 54(14), P. 3939 - 3948

Published: Oct. 1, 2024

Abstract Background Should COVID-19 have a direct impact on the risk of depression, it would suggest specific pathways for prevention and treatment. In this retrospective population-based study, we aimed to examine association prior SARS-CoV-2 infection with depressive symptoms, distinguishing self-reported v . biologically confirmed COVID-19. Methods 32 007 participants from SAPRIS survey nested in French CONSTANCES cohort were included. was measured as followed: ad hoc serologic testing, PCR or serology positive test results, Depressive symptoms Center Epidemiologic Studies-Depression Scale (CES-D). Outcomes (total CES-D score, its four dimensions, clinically significant symptoms) exposure (no COVID-19/self-reported unconfirmed COVID-19/biologically COVID-19). Results comparison without COVID-19, had higher scores ( β one interquartile range increase [95% CI]: 0.15 [0.08–0.22] 0.09 [0.05–0.13], respectively) somatic complaints dimension (0.15 [0.09–0.21] 0.10 [0.07–0.13]). Only those but depressed affect (0.08 [0.01–0.14]). Accounting testing only, score only associated combination negative results. Conclusions The between merely driven by depression did not follow gradient consistent hypothesis depression.

Language: Английский

Citations

0