Adherence and sustainability of interventions informing optimal control against the COVID-19 pandemic DOI Creative Commons
Laura Di Domenico, C Sabbatini, Pierre‐Yves Boëlle

et al.

Communications Medicine, Journal Year: 2021, Volume and Issue: 1(1)

Published: Dec. 6, 2021

After one year of stop-and-go COVID-19 mitigation, in the spring 2021 European countries still experienced sustained viral circulation due to Alpha variant. As prospect entering a new pandemic phase through vaccination was drawing closer, key challenge remained on how balance efficacy long-lasting interventions and their impact quality life.Focusing third wave France during 2021, we simulate intervention scenarios varying intensity duration, with potential waning adherence over time, based past mobility data modeling estimates. We identify optimal strategies by balancing data-driven "distress" index, integrating duration social distancing.We show that moderate would require much longer time achieve same result as high lockdowns, additional risk deteriorating control wanes. Shorter strict lockdowns are largely more effective than for similar intermediate distress infringement individual freedom.Our study shows favoring milder stringent short approaches basis perceived acceptability could be detrimental long term, especially adherence.In distancing measures were strengthened cases. While such needed slow spread virus, they have significant population’s life. Here, use mathematical modelling hospital admission behavioural health (including mobility, indicators distancing, perception, mental health) evaluate strategies. look at effects interventions, sustainability them time. find shorter, likely healthcare burden long-lasting, less but sustainable interventions. Our findings implications design implementation public future waves.

Language: Английский

Correlation between UV Index, Temperature and Humidity with Respect to Incidence and Severity of COVID 19 in Spain DOI Open Access
Juan Blas Pérez-Gilaberte,

Natalia Martín-Iranzo,

José Aguilera

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2023, Volume and Issue: 20(3), P. 1973 - 1973

Published: Jan. 20, 2023

Various studies support the inverse correlation between solar exposure and Coronavirus SARS-CoV-2 infection. In Spain, from Canary Islands to northern part of country, global incidence COVID-19 is different depending on latitude, which could be related meteorological conditions such as temperature, humidity, ultraviolet index (UVI). The objective present work was analyze association UVI, other relevant environmental factors temperature incidence, severity, mortality at latitudes in Spain.An observational prospective study conducted, recording numbers new cases, hospitalizations, patients critical units, rates, annual variations humidity five provinces Spain January 2020 February 2021.Statistically significant correlations (Spearman coefficients) were observed changes, cases almost all latitudes.Higher radiation levels mean temperatures contribute reducing mortality.

Language: Английский

Citations

13

Modelling Impact of High-Rise, High-Density Built Environment on COVID-19 Risks: Empirical Results from a Case Study of Two Chinese Cities DOI Open Access
Yong Xu, Chunlan Guo,

Jinxin Yang

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2023, Volume and Issue: 20(2), P. 1422 - 1422

Published: Jan. 12, 2023

Characteristics of the urban environment (e.g., building density and road network) can influence spread transmission coronavirus disease 2019 (COVID-19) within cities, especially in high-density high-rise built environments. Therefore, it is necessary to identify key attributes environments enhance modelling COVID-19. To this end, case studies for testing development were performed two densely populated Chinese cities with high-rise, (Hong Kong Shanghai).The investigated environmental features included 2D 3D morphological indices sky view factor, floor area ratio, frontal density, height width coverage ratio), socioeconomic demographic population), public service points-of-interest bus stations clinics). The effects on infection rate are notable communities. As spatial scale becomes larger, effect factors ratio) more notable. several ratio population density) at different scales be considered when risk findings study clarify how applied predict infectious diseases. This knowledge used develop effective planning strategies prevent control epidemics ensure healthy cities.

Language: Английский

Citations

12

Issue 4 - Impact of air pollution on COVID-19 mortality and morbidity: An epidemiological and mechanistic review DOI Creative Commons
Hasan Bayram, Nur Konyalılar,

Müge Akpinar Elçi

et al.

Pulmonology, Journal Year: 2024, Volume and Issue: unknown

Published: May 1, 2024

Air pollution is a major global environment and health concern. Recent studies have suggested an association between air COVID-19 mortality morbidity. In this context, close increased levels of pollutants such as particulate matter ≤2.5 to 10 µM, ozone nitrogen dioxide SARS-CoV-2 infection, hospital admissions due COVID 19 has been reported. can make individuals more susceptible infection by inducing the expression proteins angiotensin converting enzyme (ACE)2 transmembrane protease, serine 2 (TMPRSS2) that are required for viral entry into host cell, while causing impairment in defence system damaging epithelial barrier, muco-ciliary clearance, inhibiting antiviral response immune dysregulation. The aim review report epidemiological evidence on impact up-to-date manner, well provide insights vivo vitro mechanisms.

Language: Английский

Citations

4

Predicting the effective reproduction number of COVID-19: inference using human mobility, temperature, and risk awareness DOI Creative Commons
Sung-mok Jung, Akira Endo, Andrei R. Akhmetzhanov

et al.

International Journal of Infectious Diseases, Journal Year: 2021, Volume and Issue: 113, P. 47 - 54

Published: Oct. 9, 2021

The effective reproduction number (Rt) has been critical for assessing the effectiveness of countermeasures during coronavirus disease 2019 (COVID-19) pandemic. Conventional methods using reported incidences are unable to provide timely Rt data due delay from infection reporting. Our study aimed develop a framework predicting in real time, accessible - i.e. human mobility, temperature, and risk awareness.A linear regression model predict was designed embedded renewal process. Four prefectures Japan with high first wave were selected fitting validation. Predictive performance assessed by comparing observed predicted cross-validation, testing on separate dataset two other distinct geographical settings four studied prefectures.The mean values 95% uncertainty intervals followed overall trends incidence, while predictive diminished when changed abruptly, potentially superspreading events or stringent implemented.The described can be used monitoring transmission dynamics COVID-19 ahead formal estimates, subject delay, providing essential information planning assessment countermeasures.

Language: Английский

Citations

26

Adherence and sustainability of interventions informing optimal control against the COVID-19 pandemic DOI Creative Commons
Laura Di Domenico, C Sabbatini, Pierre‐Yves Boëlle

et al.

Communications Medicine, Journal Year: 2021, Volume and Issue: 1(1)

Published: Dec. 6, 2021

After one year of stop-and-go COVID-19 mitigation, in the spring 2021 European countries still experienced sustained viral circulation due to Alpha variant. As prospect entering a new pandemic phase through vaccination was drawing closer, key challenge remained on how balance efficacy long-lasting interventions and their impact quality life.Focusing third wave France during 2021, we simulate intervention scenarios varying intensity duration, with potential waning adherence over time, based past mobility data modeling estimates. We identify optimal strategies by balancing data-driven "distress" index, integrating duration social distancing.We show that moderate would require much longer time achieve same result as high lockdowns, additional risk deteriorating control wanes. Shorter strict lockdowns are largely more effective than for similar intermediate distress infringement individual freedom.Our study shows favoring milder stringent short approaches basis perceived acceptability could be detrimental long term, especially adherence.In distancing measures were strengthened cases. While such needed slow spread virus, they have significant population’s life. Here, use mathematical modelling hospital admission behavioural health (including mobility, indicators distancing, perception, mental health) evaluate strategies. look at effects interventions, sustainability them time. find shorter, likely healthcare burden long-lasting, less but sustainable interventions. Our findings implications design implementation public future waves.

Language: Английский

Citations

26